Patents by Inventor David A. Woodhall

David A. Woodhall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210388312
    Abstract: Provided herein are methods of making microorganisms modified for increased xylose consumption as compared to unmodified microorganisms. The methods include providing xylose-consuming microorganisms comprising two or more copies of a nucleic acid sequence encoding xylose isomerase and two or more copies of a nucleic acid sequence encoding a xylose kinase, culturing the microorganisms in medium containing xylose and harvesting a portion of the microorganisms. These steps are repeated multiple times. The microorganisms are then isolated. The isolated microorganisms have increased xylose consumption rates compared to control xylose-consuming microorganisms. Also provided are a population of microorganisms made by the provided methods. Methods of culturing the population of microorganisms and methods of reducing xylitol production in cultures comprising the population of microorganisms are provided.
    Type: Application
    Filed: October 21, 2019
    Publication date: December 16, 2021
    Applicant: MARA RENEWABLES CORPORATION
    Inventors: Kimberly Hyson, Nathalia Florez, Denise Muise, Alexandra Merkx-Jacques, Dorothy Dennis, David Woodhall, Zachary Sun, Roberto E. Armenta
  • Publication number: 20200325465
    Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.
    Type: Application
    Filed: April 30, 2020
    Publication date: October 15, 2020
    Inventors: Alexandra Merkx-Jacques, David Woodhall, Mark Scaife, Roberto E. Armenta, Denise Muise, Holly Rasmussen, Jeremy Benjamin
  • Patent number: 10662418
    Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: May 26, 2020
    Assignee: Mara Renewables Corporation
    Inventors: Alexandra Merkx-Jacques, David Woodhall, Mark Scaife, Roberto E. Armenta, Denise Muise, Holly Rasmussen, Jeremy Benjamin
  • Publication number: 20180291363
    Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.
    Type: Application
    Filed: March 12, 2018
    Publication date: October 11, 2018
    Applicant: MARA Renewables Corporation
    Inventors: Alexandra Merkx-Jacques, David Woodhall, Mark Scaife, Roberto E. Armenta, Denise Muise, Holly Rasmussen, Jeremy Benjamin
  • Patent number: 9951326
    Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: April 24, 2018
    Inventors: Alexandra Merkx-Jacques, David Woodhall, Mark Scaife, Roberto E. Armenta, Denise Muise, Holly Rasmussen, Jeremy Benjamin
  • Publication number: 20170015988
    Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.
    Type: Application
    Filed: July 13, 2016
    Publication date: January 19, 2017
    Applicant: MARA Renewables Corporation
    Inventors: Alexandra Merkx-Jacques, David Woodhall, Mark Scaife, Roberto E. Armenta, Denise Muise, Holly Rasmussen, Jeremy Benjamin
  • Patent number: 5398901
    Abstract: A support for a television etc. has a platform 12 with a central spherical recess 18. The recess sits on a support member 22 which can slide along an arm 28. A bolt 30 extends down through a slot 20 in the recess 18, through apertures or bores 34 in the arm 28 and engages a member 42. The recess 18 forms a ball and socket joint on the member 22 which allows the platform to be tilted and swiveled unless the member 42 is tightened sufficiently to clamp the sliding surfaces together, preventing further movement.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: March 21, 1995
    Assignee: Haropa Products Limited
    Inventors: Harry Brodmann, David A. Woodhall