Patents by Inventor David Aaron Schwartz
David Aaron Schwartz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230326346Abstract: This document describes techniques for performing track associations at least partially based on low confidence detections. For object trackers, which rely on measurement detections that are associated with a reported confidence, there is no direct tradeoff between a true positive track rate and a false positive track rate that applies to improving the accuracy of state estimates of tracks. To increase the true positive track rate while reducing the false positive track rate, a parameter is maintained for each track. Referred to as Probability of Existence (PoE), it is an estimate of likelihood that a real object exists with a true state that approximates an estimated state for that track. By considering PoE in combination with the reported confidence in the measurement detections being used, object tracking using radar and other sensors technologies is improved, so real-objects are reported more-quickly and accurately, and false objects are reported less often.Type: ApplicationFiled: April 8, 2022Publication date: October 12, 2023Inventor: David Aaron Schwartz
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Patent number: 11511753Abstract: An illustrative example method is for estimating a friction characteristic of a surface beneath a vehicle that has a plurality of wheels contacting the surface. The method includes determining a wheel speed of at least one of the wheels, determining a velocity of the at least one of the wheels separately from determining the wheel speed, determining a wheel slip of the at least one of the wheels based on the determined wheel speed and the determined velocity, and determining the friction characteristic based on the determined wheel slip. Determining the velocity separately from the wheel speed is accomplished using at least one detector that provides an output corresponding to a range rate, such as a RADAR or LIDAR detector.Type: GrantFiled: October 26, 2020Date of Patent: November 29, 2022Assignee: APTIV TECHNOLOGIES LIMITEDInventors: Jan Schiffmann, Henrik Clasen, David Aaron Schwartz, Amith Somanath
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Publication number: 20220308198Abstract: This document describes radar tracking with model estimates augmented by radar detections. An example tracker analyzes information derived using radar detections to enhance radar tracks having object measurements estimated from directly analyzing data cubes with a model (e.g., a machine-learning model). High-quality tracks with measurements to objects of importance can be quickly produced with the model. However, the model only estimates measurements for classes of objects its training or programming can recognize. To improve estimated measurements from the model, or even in some cases, to convey additional classes of objects, the tracker separately analyzes detections. Detections that consistently align to objects recognized by the model can update model-derived measurements conveyed initially in the tracks. Consistently observed detections that do not align to existing tracks may be used to establish new tracks for conveying more classes of objects than the model can recognize.Type: ApplicationFiled: February 2, 2022Publication date: September 29, 2022Inventors: Jan K. Schiffmann, David Aaron Schwartz, Susan Yu-Ping Chen, Nianxia Cao
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Publication number: 20220132956Abstract: The present invention is directed to a garment for assisting a user to instantaneously visualize and remember a coordinated movement of body segments at the moment before and/or during the task. The coordinated movement can be related to any physical task such as sports, therapy, aerobics, dance, etc. The garment according to the present invention comprises an arrangement of arrows in or on a fabric of the garment, wherein the position of the arrows relative to body segments and the direction of the arrows indicates the direction in which the related body segment should be moved and/or aligned.Type: ApplicationFiled: November 5, 2020Publication date: May 5, 2022Inventor: David Aaron Schwartz
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Publication number: 20220126834Abstract: An illustrative example method is for estimating a friction characteristic of a surface beneath a vehicle that has a plurality of wheels contacting the surface. The method includes determining a wheel speed of at least one of the wheels, determining a velocity of the at least one of the wheels separately from determining the wheel speed, determining a wheel slip of the at least one of the wheels based on the determined wheel speed and the determined velocity, and determining the friction characteristic based on the determined wheel slip. Determining the velocity separately from the wheel speed is accomplished using at least one detector that provides an output corresponding to a range rate, such as a RADAR or LIDAR detector.Type: ApplicationFiled: October 26, 2020Publication date: April 28, 2022Inventors: Jan SCHIFFMANN, Henrik CLASEN, David Aaron SCHWARTZ, Amith SOMANATH
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Patent number: 6670393Abstract: The present invention provides novel carbamate-based cationic lipids of the general structure: or a salt, or solvate, or enantiomers thereof, wherein (a) R1 is a lipophilic moiety; (b) R2 is a positively charged moiety; (c) n is an integer from 1 to 8; (d) X is an anion or polyanion; and (e) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid. The present invention further provides compositions of these lipids with polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions, and a kit for preparing the same.Type: GrantFiled: June 25, 2001Date of Patent: December 30, 2003Assignee: Promega Biosciences, Inc.Inventors: David Aaron Schwartz, Bob Dale Brown, Brian Patrick Dwyer
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Patent number: 6638529Abstract: The present invention provides novel amide-based cationic lipids of the general structure: or a salt, or solvate, or enantiomers thereof wherein; (a) Y is a direct link or an alkylene of 1 to about 20 carbon atoms; (b) R1 is H or a lipophilic moiety; (c) R2, R3, and R4 are positively charged moieties, or at least one but not all of R2, R3, or R4 is a positive moiety and the remaining are independently selected from H, an alkyl moiety of 1 to about 6 carbon atoms, or a heterocyclic moiety of about 5 to about 10 carbon atoms; (d) n and p are independently selected integers from 0 to 8, such that the sum of n and o is from 1 to 16; (e) X− is an anion or polyanion and (f) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid; provided that if Y is a direct link and the sum of n and p is 1 then one of either R3 or R4 must have an alkyl moiety of at least 10 carbon atoms.Type: GrantFiled: January 14, 2002Date of Patent: October 28, 2003Assignee: Genta IncorporatedInventors: David Aaron Schwartz, William J. Daily, Brian Patrick Dwyer, Kumar Srinivasan, Bob Dale Brown
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Publication number: 20030097011Abstract: The present invention provides novel carbamate-based cationic lipids of the general structure: 1Type: ApplicationFiled: June 25, 2001Publication date: May 22, 2003Applicant: Promega Biosciences, Inc.Inventors: David Aaron Schwartz, Bob Dale Brown, Brian Patrick Dwyer
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Publication number: 20020156237Abstract: The present invention provides novel amide-based cationic lipids of the general structure: 1Type: ApplicationFiled: January 14, 2002Publication date: October 24, 2002Applicant: Promega Biosciences, Inc.Inventors: David Aaron Schwartz, William J. Daily, Brian Patrick Dwyer, Kumar Srinivasan, Bob Dale Brown
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Patent number: 6339173Abstract: The present invention provides novel amide-based cationic lipids of the general structure: or a salt, or solvate, or enantiomers thereof wherein; (a) Y is a direct link or an alkylene of 1 to about 20 carbon atoms; (b) R1 is H or a lipophilic moiety; (c) R2, R3, and R4 are positively charged moieties, or at least one but not all of R2,R3, or R4 is a positive moiety and the remaining are independently selected from H, an alkyl moiety of 1 to about 6 carbon atoms, or a heterocyclic moiety of about 5 to about 10 carbon atoms; (d) n and p are independently selected integers from 0 to 8, such that the sum of n and o is from 1 to 16; (e) X− is an anion or polyanion and (f) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid; provided that if Y is a direct link and the sum of n and p is 1 then one of either R3 or R4 must have an alkyl moiety of at least 10 carbon atoms.Type: GrantFiled: June 7, 1999Date of Patent: January 15, 2002Assignee: Promega Biosciences, Inc.Inventors: David Aaron Schwartz, William J. Daily, Brian Patrick Dwyer, Kumar Srinivasan, Bob Dale Brown
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Patent number: 6251939Abstract: The present invention provides novel carbamate-based cationic lipids of the general structure: or a salt, or solvate, or enantiomers thereof, wherein (a) R1 is a lipophilic moiety; (b) R2 is a positively charged moiety; (c) n is an integer from 1 to 8; (d) X is an anion or polyanion; and (e) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid. The present invention further provides compositions of these lipids with polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions, and a kit for preparing the same.Type: GrantFiled: June 5, 1996Date of Patent: June 26, 2001Assignee: Promega Biosciences, Inc.Inventors: David Aaron Schwartz, Bob Dale Brown, Brian Patrick Dwyer
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Patent number: 6172049Abstract: The present invention provides novel phosphonic acid-based cationic lipids of the general structure: or a salt, or solvate, or enantiomers thereof wherein; (a) R1 is a lipophilic moiety; (b) R2 is a positively charged moiety; (c) R3 is a lipophilic moiety of 1 to about 24 carbon atoms, a positively charged moiety, or a negatively charged moiety; (d) n is an integer from 0 to 8; (e) X− is an anion or polyanion; (f) Y is N or 0, and (g) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid. The present invention further provides compositions of these lipids with polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions and a kit for preparing the same.Type: GrantFiled: June 7, 1999Date of Patent: January 9, 2001Assignee: Promega Biosciences, Inc.Inventors: Brian Patrick Dwyer, Alexandre V. Lehedev, Bob Dale Brown, David Aaron Schwartz
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Patent number: 6034135Abstract: The present invention provides novel dimeric cationic lipids. The present invention further provides compositions of these lipids with anionic or polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions and a kit for preparing the same.Type: GrantFiled: March 6, 1997Date of Patent: March 7, 2000Assignee: Promega Biosciences, Inc.Inventors: David Aaron Schwartz, Brian Patrick Dwyer, William J. Daily, Kumar Srinivasan, Bob Dale Brown
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Patent number: 6028188Abstract: Oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.Type: GrantFiled: November 21, 1994Date of Patent: February 22, 2000Assignee: Genta IncorporatedInventors: Lyle John Arnold, Jr., Richard Isais Hogrefe, Mark Alan Reynolds, Timothy Andrew Riley, David Aaron Schwartz, Morteza Monir Vaghefi, Bob Dale Brown
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Patent number: 6020526Abstract: The present invention provides novel amide-based cationic lipids of the general structure: ##STR1## or a salt, or solvate, or enantiomers thereof wherein; (a) Y is a direct link or an alkylene of 1 to about 20 carbon atoms; (b) R.sub.1 is H or a lipophilic moiety; (c) R.sub.2, R.sub.3, and R.sub.4 are positively charged moieties, or at least one but not all of R.sub.2, R.sub.3, or R.sub.4 is a positive moiety and the remaining are independently selected from H, an alkyl moiety of 1 to about 6 carbon atoms, or a heterocyclic moiety of about 5 to about 10 carbon atoms; (d) n and p are independently selected integers from 0 to 8, such that the sum of n and o is from 1 to 16; (e) X.sup.- is an anion or polyanion and (f) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid; provided that if Y is a direct link and the sum of n and p is 1 then one of either R.sub.3 or R.sub.4 must have an alkyl moiety of at least 10 carbon atoms.Type: GrantFiled: July 22, 1996Date of Patent: February 1, 2000Assignee: Genta, IncorporatedInventors: David Aaron Schwartz, William J. Daily, Brian Patrick Dwyer, Kumar Srinivasan, Bob Dale Brown
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Patent number: 5958901Abstract: The present invention provides novel phosphonic acid-based cationic lipids of the general structure: ##STR1## or a salt, or solvate, or enantiomers thereof wherein; (a) R.sub.1 is a lipophilic moiety; (b) R.sub.2 is a positively charged moiety; (c) R.sub.3 is a lipophilic moiety of 1 to about 24 carbon atoms, a positively charged moiety, or a negatively charged moiety; (d) n is an integer from 0 to 8; (e) X.sup.- is an anion or polyanion; (f) Y is N or O, and (g) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid.The present invention further provides compositions of these lipids with polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions and a kit for preparing the same.Type: GrantFiled: June 5, 1996Date of Patent: September 28, 1999Assignee: Genta IncorporatedInventors: Brian Patrick Dwyer, Alexandre V. Lehedev, Bob Dale Brown, David Aaron Schwartz
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Patent number: 5955597Abstract: Oligomers having phosphonate internucleosidyl linkages which are enriched for phosphonate linkages of a preselected chirality which hybridize to an RNA target sequence and methods for their preparation are provided.Type: GrantFiled: June 30, 1997Date of Patent: September 21, 1999Assignee: Genta, IncorporatedInventors: Lyle John Arnold, Jr., Mark Alan Reynolds, Timothy Andrew Riley, David Aaron Schwartz, Morteza Monir Vaghefi
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Patent number: 5877220Abstract: The present invention provides amide-based oligomeric cationic lipids. The present invention further provides compositions of these amide-based cationic lipids with anionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions and a kit for preparing the same.Type: GrantFiled: March 6, 1997Date of Patent: March 2, 1999Assignee: Genta, IncorporatedInventors: David Aaron Schwartz, Brian Patrick Dwyer, William J. Daily, Kumar Srinivasan, Bob Dale Brown
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Patent number: 5789576Abstract: Processes for the stereospecific synthesis of 2',2"-bis(deoxy)di-nucleosides and for the stereoselective synthesis of 2',2"-bis(substituted) dinucleosides are provided. Also provided are activated 2'-substituted-nucleoside alkylphosphonate active esters useful in the synthesis of these dinucleosides.Type: GrantFiled: December 9, 1994Date of Patent: August 4, 1998Assignee: Genta IncorporatedInventors: William J. Daily, David Aaron Schwartz