Patents by Inventor David Adam Stein

David Adam Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTISENSE THERAPEUTICS FOR BETACORONAVIRUS TREATMENT
    Publication number: 20230203492
    Abstract: Disclosed herein are embodiments of a compound useful for treating or preventing betacoronavirus infections such as SARS-Cov-2 infections. Also disclosed is a method for administering the compound to a subject, particularly a human subject, to treat or prevent a betacoronavirus infection in the subject. The compound can comprise an oligomer comprising a nucleic acid base sequence that is antisense to at least a portion of a SARS-CoV-2 genomic RNA, and can comprise a sequence present in the 5? UTR and first 20 nt of coding sequence of the SARS-CoV-2 genomic RNA. The compound also can contain a peptide sequence. In some embodiments, the compound is a peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO).
    Type: Application
    Filed: November 7, 2022
    Publication date: June 29, 2023
    Applicants: Oregon State University, The U.S.A., as Represented by the Secretary, Department of Health and Human Services
    Inventors: Hong M. Moulton, David Adam Stein, Heinrich Ulrich Feldmann, Kyle Ture Rosenke