Patents by Inventor David Adle

David Adle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHOD OF USE OF THE SAME FOR PRESERVING CELLS FOR ANALYSIS
    Publication number: 20240114894
    Abstract: Stabilizing compositions for stabilizing a post-draw, but pre-analysis sample include, a saccharide, at least one heavy metal salt, and a pH from 5.9 to 8.0. The stabilizing compositions may include an aliphatic aldehyde, a buffer, and a preservative. The stabilizing compositions stabilize a sample for analysis. The analysis preformed on the stabilized cell may determine the state of a condition of interest, quantification of absolute cell counts, cellular activity, and qualitative analysis of cell types. Stabilizing a sample means that cells of the sample retain their biophysical properties, including biophysical properties of cell surface markers, for analysis. Preferably, the stabilizing compositions and methods may stabilize a sample for at least 16 days, and up to 30 days. The stabilizing compositions and methods may stabilize a sample for up to 180 days.
    Type: Application
    Filed: December 15, 2023
    Publication date: April 11, 2024
    Applicant: Chryos, LLC
    Inventors: Gregory R. Post, David Adle
  • Composition and method of use of the same for preserving cells for analysis
    Patent number: 11882823
    Abstract: Stabilizing compositions for stabilizing a post-draw, but pre-analysis sample include, a saccharide, at least one heavy metal salt, and a pH from 5.9 to 8.0. The stabilizing compositions may include an aliphatic aldehyde, a buffer, and a preservative. The stabilizing compositions stabilize a sample for analysis. The analysis preformed on the stabilized cell may determine the state of a condition of interest, quantification of absolute cell counts, cellular activity, and qualitative analysis of cell types. Stabilizing a sample means that cells of the sample retain their biophysical properties, including biophysical properties of cell surface markers, for analysis. Preferably, the stabilizing compositions and methods may stabilize a sample for at least 16 days, and up to 30 days. The stabilizing compositions and methods may stabilize a sample for up to 180 days.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: January 30, 2024
    Inventors: Gregory R. Post, David Adle