Patents by Inventor David Alexander Ullisch

David Alexander Ullisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of thapsigargins by cell suspension culture
    Patent number: 10822628
    Abstract: The present invention relates to a method of producing sesquiterpene lactones of the thapsigargin family, the method comprising the steps of: (a) culturing plant cells of the genus Thapsia in a nutrient medium in a suspension cell culture, wherein the cells produce one or more sesquiterpene lactones of the thapsigargin family; and (b) recovering one or more sesquiterpene lactones of the thapsigargin family produced in (a). The present invention further relates to a suspension cell culture comprising plant cells of the genus Thapsia, wherein the plant cells are capable of producing one or more sesquiterpene lactones of the thapsigargin family and to a plant cell biomass comprising plant cells of the genus Thapsia obtained from said suspension cell culture.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: November 3, 2020
    Assignee: Phyton Holdings, LLC
    Inventors: Gilbert Gorr, Harald Heckenmüller, David Alexander Ullisch, Jens Stefan Wilke, Yantree Devi Sankar-Thomas
  • Production of ingenol, ingenol esters and/or tiglian-3-one derivatives by euphorbiaceae plant cell suspension cultures
    Patent number: 10172306
    Abstract: The present invention relates to a method of producing Ingenol, Ingenol esters and/or Tiglian-3-one derivatives, the method comprising the steps of: (a) culturing plant cells obtained from a plant selected from the family Euphorbiaceae in a nutrient medium in a suspension cell culture, wherein the cells produce Ingenol, one or more Ingenol esters and/or one or more Tiglian-3-one derivatives; and (b) recovering the Ingenol, the one or more Ingenol esters and/or the one or more Tiglian-3-one derivatives produced in (a). The present invention further relates to a plant suspension cell culture, wherein the cells are obtained from a plant selected from the family Euphorbiaceae, and wherein the plant cells produce Ingenol and/or one or more Ingenol ester and/or one or more Tiglian-3-one derivatives.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: January 8, 2019
    Assignee: Phyton Holdings, LLC
    Inventors: Gilbert Gorr, David Alexander Ullisch, Yantree Devi Sankar-Thomas, Thomas Selge, Thomas Leibold, Harald Heckenmüller
  • PRODUCTION OF INGENOL, INGENOL ESTERS AND/OR TIGLIAN-3-ONE DERIVATIVES BY EUPHORBIACEAE PLANT CELL SUSPENSION CULTURES
    Publication number: 20180042194
    Abstract: The present invention relates to a method of producing Ingenol, Ingenol esters and/or Tiglian-3-one derivatives, the method comprising the steps of: (a) culturing plant cells obtained from a plant selected from the family Euphorbiaceae in a nutrient medium in a suspension cell culture, wherein the cells produce Ingenol, one or more Ingenol esters and/or one or more Tiglian-3-one derivatives; and (b) recovering the Ingenol, the one or more Ingenol esters and/or the one or more Tiglian-3-one derivatives produced in (a). The present invention further relates to a plant suspension cell culture, wherein the cells are obtained from a plant selected from the family Euphorbiaceae, and wherein the plant cells produce Ingenol and/or one or more Ingenol ester and/or one or more Tiglian-3-one derivatives.
    Type: Application
    Filed: March 18, 2016
    Publication date: February 15, 2018
    Applicant: Phyton Holdings, LLC
    Inventors: Gilbert Gorr, David Alexander Ullisch, Yantree Devi Sankar-Thomas, Thomas Selge, Thomas Leibold, Harald Heckenmüller
  • PRODUCTION OF THAPSIGARGINS BY THAPSIA CELL SUSPENSION CULTURE
    Publication number: 20160312255
    Abstract: The present invention relates to a method of producing sesquiterpene lactones of the thapsigargin family, the method comprising the steps of: (a) culturing plant cells of the genus Thapsia in a nutrient medium in a suspension cell culture, wherein the cells produce one or more sesquiterpene lactones of the thapsigargin family; and (b) recovering one or more sesquiterpene lactones of the thapsigargin family produced in (a). The present invention further relates to a suspension cell culture comprising plant cells of the genus Thapsia, wherein the plant cells are capable of producing one or more sesquiterpene lactones of the thapsigargin family and to a plant cell biomass comprising plant cells of the genus Thapsia obtained from said suspension cell culture.
    Type: Application
    Filed: December 2, 2014
    Publication date: October 27, 2016
    Applicant: Phyton Holdings, LLC
    Inventors: Gilbert Gorr, Harald Heckenmuller, David Alexander Ullisch, Jens Stefan Wilke, Yantree Devi Sankar-Thomas