Patents by Inventor David-Alexandre Gros

David-Alexandre Gros has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DOSING METHODS FOR TREATMENT OF CARDIOVASCULAR CONDITIONS
    Publication number: 20230210845
    Abstract: The invention provides methods of treating cardiovascular conditions and methods of increasing the efficiency of cardiac metabolism.
    Type: Application
    Filed: May 3, 2021
    Publication date: July 6, 2023
    Inventors: Jaikrishna Patel, Paul Chamberlin, David-Alexandre Gros, Larry Tremaine
  • METHODS OF ALTERING CARDIAC REMODELING USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION
    Publication number: 20220249463
    Abstract: The invention provides methods for altering cardiac remodeling in a subject by providing a compound that shifts cellular metabolism from fatty acid oxidation to glucose oxidation.
    Type: Application
    Filed: May 27, 2020
    Publication date: August 11, 2022
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel
  • METHODS OF TREATING FIBROSIS USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION
    Publication number: 20220241272
    Abstract: The invention provides methods for treating or preventing fibrosis in a subject by providing a compound that shifts cellular metabolism from fatty acid oxidation to glucose oxidation.
    Type: Application
    Filed: May 27, 2020
    Publication date: August 4, 2022
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel
  • METHODS OF TREATING CANCER USING TRIMETAZIDINE-BASED COMPOUNDS
    Publication number: 20220168431
    Abstract: The invention provides compositions and methods for treating a subject having cancer.
    Type: Application
    Filed: March 13, 2020
    Publication date: June 2, 2022
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel
  • METHODS OF TREATING RHEUMATIC DISEASES USING TRIMETAZIDINE-BASED COMPOUNDS
    Publication number: 20210353617
    Abstract: The invention provides compositions and methods for treating a subject having a rheumatic condition.
    Type: Application
    Filed: October 10, 2019
    Publication date: November 18, 2021
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jalkrishna Patel
  • COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING LEBER'S HEREDITARY OPTIC NEUROPATHY
    Publication number: 20210346332
    Abstract: Compositions and methods for treating and preventing Leber's hereditary optic neuropathy are provided.
    Type: Application
    Filed: October 10, 2019
    Publication date: November 11, 2021
    Inventors: Andrew D. Levin, David-Alexandre Gros
  • TCA CYCLE INTERMEDIATES AND METHODS OF USE THEREOF
    Publication number: 20210346329
    Abstract: The invention generally relates to non-oral formulations of TCA cycle intermediates and methods of using such formulations for treating metabolic disorders. In certain embodiments, the invention provides therapeutic compositions containing succinate formulated for non-oral administration and methods of using such compositions to treat metabolic disorders. The invention also provides combination therapies that include compositions containing succinate formulated for non-oral administration and compositions containing citrate (optionally formulated for oral administration) and methods of using such combination therapies to treat metabolic disorders.
    Type: Application
    Filed: October 10, 2019
    Publication date: November 11, 2021
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel