Abstract: The present invention generally relates to processes for reducing the rate of pressure drop increase in a vessel used for hydrogenation of aldehydes to alcohols. In one embodiment, the process comprises replacing a first set of catalyst pellets with a second set of catalyst pellets, wherein the second set of catalyst pellets have a higher average aspect ratio than the first set of catalyst pellets, a different shape than the first set of catalyst pellets, or a combination thereof, and wherein a void fraction of the second set of catalyst pellets is greater than the void fraction of the first set of catalyst pellets, wherein a pressure drop rate increase of the vessel partially filled with the second set of catalyst pellets is less than a pressure drop rate increase of the vessel partially filled with the first set of catalyst pellets when operated under substantially similar conditions.

Abstract: An equipment bag attachment mechanism detachably secures two equipment bags to each other for easy collective or individual transport. In embodiments, the equipment bags may be selected from among a helmet bag, a boot bag, and a grooming bag. In embodiments, the mechanism includes a first attachment mechanism portion that includes a pair of opposed tongues, one of the tongues having a downwardly extending protrusion, and a second attachment mechanism portion that includes a loop that seats between the opposed tongues and is limited by the protrusion to hold the two mechanism portions together.

Abstract: A method of rendering an image of a 3-D scene includes rendering a noisy image; and obtaining one or more guide channels. For each of a plurality of local neighbourhoods, the method comprises: calculating the parameters of a model that approximates the noisy image as a function of the one or more guide channels, and applying the calculated parameters to produce a denoised image. Tiling is used when calculating the parameters of the model.

Abstract: A wiring assembly including a flex circuit including a plastic laminate layer and a mount location configured to receive a fastener secured to a substrate. The wiring assembly further includes a flex circuit attachment feature, the flex circuit attachment feature including an extruded material bonded to the plastic laminate layer at the mount location. The flex circuit attachment feature provides a structural strength at the mount location and provides a cushion between the flex circuit and the substrate.

Abstract: Systems and methods for detecting cardiac arrhythmias such as atrial tachyarrhythmia (AT) are discussed. An exemplary system includes an arrhythmia detector circuit that can receive physiologic information sensed from a patient over time, detect an arrhythmia onset when the physiologic information during a first time period satisfies an onset condition, and in response to the detected arrhythmia onset, detect an arrhythmia termination when the physiologic information during a second time period, subsequent to and longer than the first time period, satisfies an exit condition. An arrhythmia episode can be detected based on an arrhythmia duration between the detected onset and termination. The detected sustained arrhythmia episode can be provided to a user or a processor for further processing.

Abstract: A facility readiness inspection system and method are disclosed. Embodiments comprise an asset database comprising inspection task definition for assets. An inspection coordination application program interface (API) can create at least one periodic inspection task list. Each periodic inspection task list can include a number of tasks and assets, chosen based on the total time allotted for completion of the periodic inspection task list and the complexity of the inspection task definitions of each physical asset. Mobile electronic device can be configured to present the periodic inspection task list as a series of discrete tasks and to receive task list response data in response to each discrete task. Response data can be compared to benchmarks and standards, and issues can be escalated to external systems. An analytics engine can automatically produce inspection compliance documentation for each of the physical assets related to the periodic inspection task list.

Abstract: An example computing device includes a body and a first display device including a lower end that is pivotably connected to the body and a front surface including a first display area. The computing device further includes a second display device including a pivotable end that is pivotably connected to the body and a free end opposite the pivotable end. The computing device further includes a bias member connecting the second display device to the first display device. The bias member resiliently urges the free end of the second display device towards the front surface of the first display device.

Abstract: The radio frequency front-end systems herein include modules having bandwidth controllable components, such as amplifier and filters. By implementing the modules with bandwidth control, the same module can be used for operation of multiple frequency bands including a first frequency band and a second frequency band. Thus, when implementing features such as carrier aggregation, multiple-input multiple-output (MIMO), and/or sounding resource signaling (SRS) for supporting the multiple frequency bands, the total number of modules used can be reduced and/or additional feature support can be provided compared to an implementation in which each module supports a single frequency band.

Abstract: In a preferred embodiment, a pistol compensator system comprises a compensator, an elastomeric spacer, an assortment of variously sized shims, a spring guide rod, and a spring plug. The compensator of this system comprises a body, a barrel cavity, a threaded bore, an oval rod cavity, and a plug cavity. The spring plug of this system comprises a latch extension. The spring guide rod of this system comprises a muzzle end. When this preferred embodiment is installed on a pistol, if the pistol is in battery (slide closed) the latch extension is disposed in the plug cavity, and if the pistol is out of battery (slide back) the muzzle end of the guide rod is disposed in the rod cavity. In this preferred embodiment, the compensator is tensioned to the end of the barrel by the elastomeric spacer and a shim.

Abstract: A liquid biopsy system and method for the detection of biomarkers in bodily fluids is described. In particular, the system is suitable for detecting biomarkers of lung cancer in a subject.

Abstract: A system (100) for providing a timing signal with tunable temperature dependency in an electronic device may include a timing circuit (102) and an initial setting circuit (104). The timing circuit (102) may include a delay stage (106) and a gate stage (108). The delay stage (106) may be configured to receive an input signal and to produce a delayed signal by introducing a delay to the input signal. The gate stage (108) may be configured to receive the delayed signal and a threshold setting signal, to produce an output signal using the delayed signal and a logic threshold, and to set an initial value of the logic threshold according to the threshold setting signal. The initial setting circuit (104) may be configured to allow the threshold setting signal to be tuned for providing the time delay with a specified temperature dependency.

Abstract: The present disclosure generally relates to dynamic and adaptive systems and methods for rewarding and/or disincentivizing behaviors.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: An assembly for replacement of a native aortic heart valve includes a radially collapsible prosthetic heart valve and a delivery apparatus. The prosthetic heart valve includes an annular frame with attachment posts, wherein each of the posts has an axial post portion and a transverse post portion having a greater circumferential dimension than the axial post portion. The delivery apparatus includes an inner shaft with a valve connection portion for releasably coupling to the attachment posts and an outer shaft having a sheath for maintaining the prosthetic heart valve in a radially compressed state. Rotation of a control knob on a handle causes the sheath to retract for uncovering a portion of the prosthetic heart valve. Further rotation of the control knob allows the posts to decouple from the delivery apparatus such that the prosthetic heart valve self-expands to a fully expanded state.

Abstract: Autonomous driving is one of the world's most challenging computational problems. Very large amounts of data from cameras, RADARs, LIDARs, and HD-Maps must be processed to generate commands to control the car safely and comfortably in real-time. This challenging task requires a dedicated supercomputer that is energy-efficient and low-power, complex high-performance software, and breakthroughs in deep learning AI algorithms. To meet this task, the present technology provides advanced systems and methods that facilitate autonomous driving functionality, including a platform for autonomous driving Levels 3, 4, and/or 5. In preferred embodiments, the technology provides an end-to-end platform with a flexible architecture, including an architecture for autonomous vehicles that leverages computer vision and known ADAS techniques, providing diversity and redundancy, and meeting functional safety standards.

Abstract: A folding joint and a folding bicycle frame are provided. The folding joint includes a hand lever, a first joint connected to a first connecting member, and a second joint connected to a second connecting member, where the hand lever is hinged to the first joint and/or the second joint. When the first joint and the second joint are in a closed position, the hand lever is rotated to a first position. When the first joint and the second joint are in a separated position, the hand lever is rotated to a second position. The hand lever is provided with a first engaging portion. When the hand lever is in the first position, the first engaging portion is configured to engage with a second engaging portion to restrict the first joint and the second joint to be in the closed position.

Abstract: A method for generating an alignment signal that includes detecting local dimensional distortions of an alignment mark and generating the alignment signal based on the alignment mark. The alignment signal is weighted based on the local dimensional distortions of the alignment mark. Detecting the local dimensional distortions can include irradiating the alignment mark with radiation, the alignment mark including a geometric feature, and detecting one or more phase and/or amplitude shifts in reflected radiation from the geometric feature. The one or more phase and/or amplitude shifts correspond to the local dimensional distortions of the geometric feature. A parameter of the radiation, an alignment inspection location within the geometric feature, an alignment inspection location on a layer of a structure, and/or a radiation beam trajectory across the geometric feature may be determined based on the one or more detected phase and/or amplitude shifts.

Abstract: Systems and methods are directed to supply chain management. In particular, the tracking, tracing, authenticating, and reporting of supply chain events for products, is disclosed. Various embodiments can store, analyze, and track supply chain events and help to coordinate and maintain trading partner connections. Various embodiments also help to enhance patient safety, secure the supply chains for pharmaceuticals, medical devices, and other healthcare products, and help users to follow regulatory requirements.

Abstract: A decided sequence of steps selected from a set of sequences of steps defined for a control system is executed to effect control of by writing a control variable to an actuator. At each timestep, it is redecided whether the decided sequence of steps or an alternate sequence of steps is to be executed.

Abstract: The methods described herein relate to the isolation of betalam pigment color compositions from crop plants. Also described are methods of pre-harvest foliar spraying of an ethylene-releasing compound to a crop plant and the uses of extracted betalam pigment color compositions from crop plant for a food or commercial product.