Abstract: A spectral reflectance imaging device for detecting nanoparticle exosome biomarker targets includes an illumination source that illuminates a substrate with a plurality of separate wavelengths of incoherent light. The substrate includes an oxide layer and a binding agent to selectively bind nanoparticle exosome biomarker targets to the substrate. An imaging device bindings the light reflected from or transmitted through the substrate and an image processing system detects the nanoparticle exosome biomarker targets a function of the change in reflective properties of the substrate.

Abstract: A unitary multilateral junction for deployment in a wellbore, wherein the multilateral junction permits electrical power and communications signals to be established in both a lateral wellbore and a main wellbore utilizing. The unitary junction assembly generally includes a conduit with a first upper aperture, a first lower aperture and a second lower aperture where the first lower aperture is defined at the distal end of a primary passageway extending from a conduit junction and a second lower aperture defined at the distal end of a lateral passageway extending from the conduit junction. A lower wireless energy transfer mechanism is positioned along at least one of the passageways between the distal end of the passageway and the junction. The lower wireless energy transfer mechanism is in wired communication an upper energy transfer mechanism permitting electrical communication to be established across the intersection of wellbore branches utilizing the unitary junction.

Abstract: A clutch assembly includes a clutch mechanism and an energy harvesting device. The clutch mechanism includes an input member, an output member, and an actuating mechanism to govern selective torque transmission from the input member to the output member. The actuating mechanism is powered by electrical current. The energy harvesting device is electrically connected to the actuating mechanism, and the energy harvesting device is configured to scavenge available energy to generate the electrical current that powers the actuating mechanism.

Abstract: Near Field Communication (NFC) chips or tags are securely activated where at least one validation or redemption number is assigned to the chip or tag at the time of activation. Subsequent to activation, the NFC chip or tag enables secure data access via an Ancillary Device. Validation or redemption of the NFC chip or tag is also provided for.

Abstract: A method of operating a computing system to generate a model of an environment represented by a mesh is provided. The method allows to update 3D meshes to client applications in real time with low latency to support on the fly environment changes. The method provides 3D meshes adaptive to different levels of simplification requested by various client applications. The method provides local update, for example, updating the mesh parts that are changed since last update. The method also provides 3D meshes with planarized surfaces to support robust physics simulations. The method includes segmenting a 3D mesh into mesh blocks. The method also includes performing a multi-stage simplification on selected mesh blocks. The multi-stage simplification includes a pre-simplification operation, a planarization operation, and a post-simplification operation.

Abstract: There is described an edible particulate material comprising from 80% to 100% by weight based on total weight of the material of a processable, microbially released, flavour acceptable bran-like material, characterized by the following parameters: (i) mean particle size by volume (Vol. MPS) of from 5 to 100 microns; (ii) volume particle size distribution (Vol. PSD) characterized by the parameters: D90,3 less than or equal to 350 microns, and D50,3 less than or equal to 50 microns, and optionally D10,3 less than or equal to 15 microns, (iii) mean particle sphericity as measured by a Smean of greater than or equal to 0.75; (iv) where processable means has oil holding capacity (OHC) of from 0.7 to 1.5; (v) where microbially released means material has common microbes below given limits (preferably free of common microbes) (vi) where flavour acceptable denotes a lipase activity (LA) and a peroxidase activity (PA) both less than or equal to 2 U/g optionally a low degree of roasted flavour notes as defined herein.

Abstract: An inertial particle separator (IPS) for a gas turbine engine, has: a plenum circumferentially extending about a central axis and defined between an outer wall and an inner wall, the plenum having an inlet facing a circumferential direction relative to the central axis, a radius of the outer wall decreasing in an axial direction relative to the central axis between the inlet and an annular splitter extending circumferentially around the central axis and located downstream of the inlet radially between the outer wall and the inner wall, a particle outlet including an annulus radially between the outer wall and the splitter, an air outlet fluidly connectable to a compressor of the gas turbine engine and defined radially between the splitter and the inner wall.

Abstract: A movement controller of a machine uses in the context of processing a part program defining a useful processing action a parameter set having a plurality of parameters to determine, based on commands of the part program and actual values of a number of axes of the machine controlled by the movement controller, control commands for drives of the machine which are associated with the axes and to apply the determined control commands to the drives. A checking device checks the respective parameters for compliance with conditions defined by respective physical characteristics. In many cases, the checking device can determine the respective physical characteristics using other parameters of the parameter set.

Abstract: The present invention includes a novel procedure and corresponding medical devices for a Percutaneous Posterior Lumbar Interbody Fusion (PePLIF). In PePLIF, the surgeon performs the entire operation percutaneously without the use of a microscope, endoscope, or magnifying loupes. An adjustable retractor system is disclosed that enables the surgeon to percutaneously perform the surgery through accessing the facet joint (and later disc space) that was created by said retractor system. This retractor system provides the surgeon a safe area to work and operate without fear of damaging nerves, blood vessels, or other tissue. An expanding trial may be inserted into and removed from the disc space through the interior of the retractor system to determine the proper size for the expandable cage. The retractor system also enables the expandable cage to be inserted into the disc space.

Abstract: There are provided inter alia compounds capable of inhibiting retinal pigment epithelium (RPE) degeneration or geography atrophy (GA) associated with age-related macular degeneration (AMD), and methods of using the same.

Abstract: A method for identifying and characterizing a condensate entrained in a fluid using time domain analysis and frequency domain analysis to identify individual volume fraction constituents and condensates within a pipe on a real time basis and to measure the volume of the individual volume fraction constituents and condensates flowing through the pipe on a real time basis.

Abstract: Receiving point of interest zones and alerts on user devices comprises communicating, by a user computing device to a remote computing device, a request for point of interest data corresponding to points of interest within a proximity of the user device; presenting the received point of interest data; identifying a particular point of interest; and outputting an alert regarding the particular point of interest. Receiving point of interest zones on user devices comprises communicating a request for point of interest data; receiving the point of interest data from the remote network device wherein a size of the point of interest zone is determined based on a density of points of interest in the proximity of the user, and wherein the shape of the point of interest zone is expanded in a direction of travel and contracted in the opposite direction; and presenting the received point of interest data.

Abstract: An archery bow is provided including limbs and at least one power cable disposed in a track of a cam rotatably mounted to a limb. The power cable is anchored to the cams with a fastener having a shaft registered in a hole defined by a landing surface of the cam so that a power cable is trapped in a cable capture void between a head of the fastener and the landing surface. The fastener can include a radius between a fastener axis and an outer edge of the head. A separation distance can be defined between the head and the track, with a ratio of the separation distance to the radius being less than 1:1. The separation distance can be less than a diameter of the power cable. A related method of use is provided.

Abstract: A filtration system housing is provided for supporting filtration system components. The filtration system is configured to remove particulates from air. The housing comprises a plurality of walls defining a chamber for receiving pressurized air. The housing additionally comprises a reinforcing member at least partially surrounding said walls. At least one of the walls is contoured to include a spatial curvature extending along a portion of the at least one wall.

Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.

Abstract: The present disclosure relates to, inter alia, devices, systems, and methods for use in the magnetic separation of biological entities from fluid samples. This device includes a magnetic separation chamber configured to receive a fluid sample for magnetic separation, where the magnetic separation chamber includes at least two magnets mounted on the surface or in the wall of the magnetic separation chamber. The device also includes a force provider configured to move the magnetic separation chamber in a side-to-side motion to mix and/or magnetize the fluid sample. In one embodiment, the magnetic separation chamber is in a form of a sleeve and comprises a substantially central channel for loading a vessel containing the fluid sample therein. The systems and methods of the present disclosure involve the use of this device to separate biological entities from fluid samples.

Abstract: A method of scheduling user equipment, a multiple antenna network node and computer program are disclosed. The method comprises: estimating at least one access network node channel within the unlicensed band between at least one access node operable to transmit in the unlicensed band, such as a WiFi Access Point, and the multiple antenna network node. Estimating a plurality of user equipment channels within the unlicensed band between a plurality of user equipment and the multiple antenna network node. Determining a degree of channel correlation of each of the plurality of user equipment channels and the at least one access node channel. Selecting at least one of the multiple user equipment to be scheduled, using the degree of channel correlation as a selection parameter, a lower degree of channel correlation increasing a user equipment's chance of being selected. In this manner the interference that LTE transmissions from and to scheduled UEs create on the at least one access node is reduced.

Abstract: A radar system has different modes of operation. In a method for operating the radar system, at least one of one or more transmitters are configured to transmit modulated continuous-wave radio signals, while at least one of one or more receivers are configured to receive radio signals. The received radio signals include the transmitted radio signals transmitted by the one or more transmitters and reflected from objects in the environment. The method further includes selectively modifying an operational parameter of at least one of the transmitters or at least one of the receivers. The selected operational parameter is modified to meet changing operational requirements of the radar sensing system.

Abstract: A fuel system is provided that includes a fuel tank, a heat detector, and a control circuit. The digital heat detector is disposed in proximity to the fuel tank. The control circuit is coupled with the digital heat detector and is configured to detect that a thermal event has occurred. The fuel system is configured to implement an emergency countermeasure in response to the detection of the thermal event.