Abstract: In one aspect, a heat rejection apparatus is provided including an evaporative heat exchanger and a primary fan operable to direct first ambient air into an air inlet, cause the first ambient air to interact with the evaporative heat exchanger to produce heated air, and discharge the heated air from an air outlet. The heat rejection apparatus includes a plume abatement fan operable to direct second ambient air into contact with the heated air downstream of the evaporative heat exchanger and a controller operably coupled to the primary fan and the plume abatement fan. The controller has a plume abatement mode wherein the controller operates the plume abatement fan to cause the plume abatement fan to direct the second ambient air into contact with the heated air to cool the heated air and abate plume.

Abstract: The present disclosure relates to a system, method, and computer program for automatically providing similar product recommendations for sold-out products promoted on non-merchant publisher sites, wherein the similar product recommendations are filtered for publisher preferences. A computer system with a product database provides a platform that enables non-merchant publishers to search products in the database, create call-to-actions on publisher sites for products in the database, and automatically receive similar product recommendations when end users of the publisher sites attempt to purchase promoted products that are now sold out. Once a publisher creates a call-to-action for a product that subsequently becomes sold out, similar product recommendations are provided without requiring any action on the publisher's part to change the publisher's site. Similar product recommendations are tailored to each publisher to account for publisher preferences.

Abstract: The invention provides solid forms of 2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S)-oxetan-2-ylmethyl]-1H-benzimidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl) propan-2-amine salt for example, Form 1 or Form 2; as well as pharmaceutical compositions, and the uses thereof in treating diseases, conditions or disorders modulated by GLP-1R in a mammal, such as a human.

Abstract: A method for biometric authentication has the steps of sending a confidential communication to an intended recipient through the system, the intended recipient providing one or more biometric identifiers to view the communication, wherein the one or more biometric identifiers are unique to the intended recipient, the system verifying the one or more biometric identifiers against one or more stored biometric identifiers, the system accepting the one or more biometric identifiers further has the steps of the system displaying the confidential communication on the mobile device, and the user continues to provide the one or more biometric identifiers, the system continuously verifying the one or more biometric identifiers while the communication is displayed wherein when the verification is uninterrupted of fails the communication is hidden.

Abstract: A system and method are provided for quantifying greenhouse gas (GHG) emissions associated with vehicle traffic. The method includes receiving data from a plurality of devices located at a plurality of traffic intersections in a traffic network, each device comprising at least one sensor configured to obtain data from the corresponding traffic intersection; using the received data and a traffic model to determine vehicle trajectory data; using the vehicle trajectory data and an emissions model to obtain corresponding GHG emissions data; and evaluating the corresponding GHG emissions data to a baseline of GHG emissions using a GHG quantification methodology to determine a GHG reduction that can achieve a carbon offset credit.

Abstract: Described herein are compounds of Formula I: I and their pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R7, RF, t1, Y1, and Y2 are defined herein; their use as MC4R antagonists; pharmaceutical compositions containing such compounds and salts; the use of such compounds and salts to treat, for example, cachexia, anorexia, or anorexia nervosa; and intermediates and processes for preparing such compounds and salts.

Abstract: An immunoassay suitable for point of care to assess liver disease or function comprising contacting a blood sample from a subject with a specific binding agent that recognizes an epitope of ALT 1, that is not recognized by rodent antibodies when the rodent antibodies are in the presence of human plasma, to form an antigen-binding agent complex and detecting the complex using a second or further binding agent linked to or comprising a detectable reporter; and detecting liver disease or liver function in the subject contingent upon the mass concentration of AL T1 in the sample. Kits or devices comprising lagomorph antibodies or binding agents comprising the antigen binding component thereof suitable for measuring the mass concentration of ALT 1 in a blood sample from a subject to determine liver function.

Abstract: The specification describes an antibody capture process comprising (i) obtaining a biological sample comprising antibodies, (ii) contacting the biological sample with recombinant pIgR or a dIgA-binding variant, wherein the pIgR or variant binds dIgA and forms a pIgR-dIgA complex. The process may further comprise (iii) directly or indirectly assessing the level of the pIgR-dIgA complex or the level of a complex between pIgR-dIgA and an antigen of interest. There is also an antibody capture process for determining gut wall integrity in a test subject, wherein the level or ratio of SIgA to dIgA is compared to a corresponding level or ratio from a control subject. The specification provides kits embodying the process and recombinant pIgR when used for, or for use, in capturing or detecting dIgA and/or IgM.

Abstract: A haircare appliance having an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet and an attachment for a haircare appliance, the attachment including an air inlet, an air outlet. A curved surface adjacent to and downstream of the air outlet. The haircare appliance or the attachment has a curved surface adjacent to and downstream of the air outlet. The haircare appliance or the attachment is configured such that airflow exiting the air outlet generates a first force to attract hair toward the curved surface, and a second force to push hair away from the curved surface.

Abstract: A host system includes a memory and a processing device coupled to the memory to perform operations including obtaining log data from a memory sub-system of a plurality of memory sub-systems, wherein the log data reflects memory usage of a memory device of the memory sub-system, wherein the memory device is shared by the plurality of host systems, including the host system, connected to the plurality of memory sub-systems; and determining, based on the log data, a schedule of a plurality of processes running on the plurality of host systems, wherein the plurality of processes share the memory device.

Abstract: Speculative cache invalidation techniques for processing-in-memory instructions are described. In one example, a system includes a cache system including a plurality of cache levels and a cache coherence controller. The cache coherence controller is configured to perform a cache directory lookup using a cache directory. The cache directory lookup is configured to indicate whether data associated with a memory address specified by a processing-in-memory request is valid in memory. The system employs speculative evaluation logic to identify whether the data associated with the processing-in-memory request is stored in the cache system before the processing-in-memory request is transmitted to the cache coherence controller. If the data is stored in the cache system, the cache system locally invalidates or flushes the data to avoid stalling the processing-in-memory request during a cache directory lookup.

Abstract: Disclosed here are airframe component assemblies including example embodiments with a root connected to an aircraft fuselage, a free section with a connection portion with holes, a slidable attachment section formed to fit between the root and the free section, and an elastomeric retention device coupled to the root and the slidable attachment section, the elastomeric retention device configured to exert a force to pull the slidable attachment toward the root.

Abstract: Described herein are systems and methods for managing error detection in a message. A circuit can identify, based on an error detection configuration of the at least one circuit, a first portion of the message to be checked for errors before a second portion of the message is available to the at least one circuit, the first portion being less than all of the message to be checked for one or more errors. A circuit can analyze a number of bits of the first portion of the message using the at least one circuit and based on the error detection configuration. A circuit can, based on analyzing the first portion, determine whether the message includes the one or more errors. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Selectively bypassing cache directory lookups for processing-in-memory instructions is described. In one example, a system maintains information describing a status—clean or dirty—of a memory address, where a dirty status indicates that the memory address is modified in a cache and thus different than the memory address as represented in system memory. A processing-in-memory request involving the memory address is assigned a cache directory bypass bit based on the status of the memory address. The cache directory bypass bit for a processing-in-memory request controls whether a cache directory lookup is performed after the processing-in-memory request is issued by a processor core and before the processing-in-memory request is executed by a processing-in-memory component.

Abstract: The present application provides an aft plate removal tool for servicing a combustor. The combustor includes an end cover, an aft plate downstream of the end cover, and a number of tubes extending through the aft plate. The aft plate removal tool includes a base plate and a threaded rod. The base plate is attached to the end cover. Rotation of the threaded rod advances the threaded rod against the aft plate until the threaded rod pushes the aft plate off of the tubes.

Abstract: Preemptive flushing of data involved in executing a processing-in-memory command, from a cache system to main memory that is accessible by a processing-in-memory component, is described. In one example, a system includes an asynchronous flush controller that receives an indication of a subsequent processing-in-memory command to be executed as part of performing a computational task. While earlier commands of the computational task are executed, the asynchronous flush controller evicts or invalidates data elements involved in executing the subsequent processing-in-memory command from the cache system, such that the processing-in-memory command can proceed without stalling.

Abstract: This invention relates to methods of treating or preventing viral infections caused by flaviviruses, such as dengue virus, yellow fever virus, West Nile virus or Japanese encephalitis virus or infections caused by Chikungunya virus (CHIKV). The methods involve the administration of retinoic acid analogues to subjects who have, are suspected of having a flavivirus infection or infection with CHIKV, or to those who are at risk of becoming infected with a flavivirus or becoming infected with CHIKV.

Abstract: A method of repitching workpieces in an automated mass production system includes: (a) unloading a set of workpieces from a plurality of first retainers arranged at a first pitch, the unloading step including gripping of the workpieces by corresponding grippers of a repitch robot; (b) adjusting the workpieces from the first pitch to a second pitch different from the first pitch, the adjusting step including translating the grippers relative to each other from a first spacing corresponding to the first pitch to a second spacing corresponding to the second pitch; and (c) loading the workpieces into a plurality of corresponding second retainers arranged at the second pitch, the loading step including positioning and releasing the workpieces in the second retainers via the grippers.