Patents by Inventor David Ann

David Ann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • G-CSF Transferrin Fusion Proteins
    Publication number: 20130143949
    Abstract: A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
    Type: Application
    Filed: May 1, 2012
    Publication date: June 6, 2013
    Applicants: NATIONAL INSTITUTE OF HEALTH
    Inventors: Wei-Chiang SHEN, Yun BAI, David ANN, Adam WIDER
  • G-CSF transferrin fusion proteins
    Patent number: 8188032
    Abstract: A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: May 29, 2012
    Assignee: National Institutes of Health (NIH)
    Inventors: Wei-Chiang Shen, Yun Bai, David Ann, Adam Widera
  • G-CSF Transferrin Fusion Proteins
    Publication number: 20090042777
    Abstract: A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
    Type: Application
    Filed: October 8, 2004
    Publication date: February 12, 2009
    Inventors: Wei-Chiang Shen, Yun Bai, David Ann, Adam Widera
  • Methods for increasing cancer cell chemosensitivity
    Publication number: 20070160684
    Abstract: The expression of HMGA2 is often associated with neoplastic transformation. The present disclosure establishes a correlation between increased HMGA2 expression and enhanced chemosensitivity towards DNA-damaging therapeutic agents such as doxorubicin, cisplatin, and X-ray irradiation.
    Type: Application
    Filed: July 28, 2006
    Publication date: July 12, 2007
    Inventors: Yun Yen, David Ann