Patents by Inventor David Antoni ALVES

David Antoni ALVES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED HELICASES
    Publication number: 20230227799
    Abstract: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: October 18, 2022
    Publication date: July 20, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Andrew John Heron, James Anthony Clarke, Ruth Moysey, Elizabeth Jayne Wallace, Mark John Bruce, Lakmal Jayasinghe, Domenico Caprotti, Szabolcs Soeroes, Luke McNeill, David Antoni Alves, Rebecca Victoria Bowen, John Milton
  • ENZYME STALLING METHOD
    Publication number: 20230212665
    Abstract: The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Application
    Filed: December 14, 2022
    Publication date: July 6, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Andrew John Heron, David Antoni Alves, James Anthony Clarke, Marion Louise Crawford, Daniel Ryan Garalde, Graham Hall, Daniel John Turner, James White
  • Enzyme stalling method
    Patent number: 11560589
    Abstract: The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: January 24, 2023
    Assignee: Oxford Nanopore Technologies PLC
    Inventors: Andrew John Heron, David Antoni Alves, James Anthony Clarke, Marion Louise Crawford, Daniel Ryan Garalde, Graham Hall, Daniel John Turner, James White
  • Modified helicases
    Patent number: 11525126
    Abstract: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: December 13, 2022
    Assignee: Oxford Nanopore Technologies PLC
    Inventors: Andrew Heron, Anthony Clarke, Ruth Moysey, Elizabeth Jayne Wallace, Mark John Bruce, Lakmal Jayasinghe, Domenico Caprotti, Szabolcs Soeroes, Luke McNeill, David Antoni Alves, Rebecca Victoria Bowen, John Milton
  • METHOD FOR CONTROLLING THE MOVEMENT OF A POLYNUCLEOTIDE THROUGH A TRANSMEMBRANE PORE
    Publication number: 20190345550
    Abstract: The invention relates to new methods of controlling the movement of polynucleotides through transmembrane pores. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Application
    Filed: July 9, 2019
    Publication date: November 14, 2019
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark John Bruce, Andrew John Heron, Elizabeth Jayne Wallace, James White, Joseph Hargreaves Lloyd, David Antoni Alves, Domenico Caprotti, Lakmal Jayasinghe, Luke McNeill, John Milton, Antonino Puglisi, Szabolcs Soeroes
  • Method for controlling the movement of a polynucleotide through a transmembrane pore
    Patent number: 10392658
    Abstract: The invention relates to new methods of controlling the movement of polynucleotides through transmembrane pores. The invention also relates to new methods of characterizing target polynucleotides using helicases.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: August 27, 2019
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark Bruce, Andrew John Heron, Elizabeth Jayne Wallace, James White, Joseph Hargreaves Lloyd, David Antoni Alves, Domenico Caprotti, Lakmal Jayasinghe, Luke McNeill, John Milton, Antonino Puglisi, Szabolcs Soeroes
  • ENZYME STALLING METHOD
    Publication number: 20190211390
    Abstract: The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Application
    Filed: January 9, 2019
    Publication date: July 11, 2019
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, David Antoni Alves, James Anthony Clarke, Marion Louise Crawford, Daniel Ryan Garalde, Graham Hall, Daniel John Turner, James White
  • Enzyme stalling method
    Patent number: 10221450
    Abstract: The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterizing target polynucleotides using helicases.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: March 5, 2019
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, David Antoni Alves, James Anthony Clarke, Marion Louise Crawford, Daniel Ryan Garalde, Graham Hall, Daniel John Turner, James White
  • METHOD FOR CONTROLLING THE MOVEMENT OF A POLYNUCLEOTIDE THROUGH A TRANSMEMBRANE PORE
    Publication number: 20170002406
    Abstract: The invention relates to new methods of controlling the movement of polynucleotides through transmembrane pores. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Application
    Filed: September 10, 2014
    Publication date: January 5, 2017
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark Bruce, Andrew John Heron, Elizabeth Jayne Wallace, James White, Joseph Hargreaves Lloyd, David Antoni Alves, Domenico Caprotti, Lakmal Jayasinghe, Luke McNeill, John Milton, Antonino Puglisi, Szabolcs Soeroes
  • ENZYME STALLING METHOD
    Publication number: 20160010147
    Abstract: The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.
    Type: Application
    Filed: January 22, 2014
    Publication date: January 14, 2016
    Applicant: OXFORD NANOPORE TECHNOLOGIES LIMITED
    Inventors: Andrew John HERON, David Antoni ALVES, James Anthony CLARKE, Marion Louise CRAWFORD, Daniel Ryan GARALDE, Graham HALL, Daniel John TURNER, James WHITE