Patents by Inventor David Applegate
David Applegate has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250375314Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: August 27, 2025Publication date: December 11, 2025Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 12478504Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: December 13, 2024Date of Patent: November 25, 2025Assignee: Glaukos CorporationInventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Publication number: 20250312190Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: January 17, 2025Publication date: October 9, 2025Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 12419783Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: October 1, 2020Date of Patent: September 23, 2025Assignee: Glaukos CorporationInventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 12376989Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: December 13, 2024Date of Patent: August 5, 2025Assignee: Glaukos CorporationInventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Publication number: 20250107928Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: December 13, 2024Publication date: April 3, 2025Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Publication number: 20250107929Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: December 13, 2024Publication date: April 3, 2025Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 12201557Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: November 30, 2022Date of Patent: January 21, 2025Assignee: Dose Medical CorporationInventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 12201555Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: March 31, 2021Date of Patent: January 21, 2025Assignee: Dose Medical CorporationInventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Publication number: 20230293344Abstract: Disclosed herein are drug delivery punctal implants and methods of using the implants for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The physical arrangement of drugs within the punctal plugs disclosed herein results, in several embodiments, in advantageous controlled delivery of one or more drugs to the eye of a patient.Type: ApplicationFiled: January 24, 2023Publication date: September 21, 2023Inventors: Thomas W. Burns, Douglas Daniel Crimaldi, David Applegate, Kenneth Martin Curry
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Publication number: 20230090539Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: November 30, 2022Publication date: March 23, 2023Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 11564833Abstract: Disclosed herein are drug delivery punctal implants and methods of using the implants for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The physical arrangement of drugs within the punctal plugs disclosed herein results, in several embodiments, in advantageous controlled delivery of one or more drugs to the eye of a patient.Type: GrantFiled: September 23, 2016Date of Patent: January 31, 2023Assignee: GLAUKOS CORPORATIONInventors: Thomas W. Burns, Douglas Daniel Crimaldi, David Applegate, Kenneth Martin Curry
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Patent number: 11564569Abstract: An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.Type: GrantFiled: July 11, 2018Date of Patent: January 31, 2023Assignee: GLAUKOS CORPORATIONInventors: Thomas W. Burns, Harold A. Heitzmann, Kenneth Martin Curry, David S. Haffner, David Applegate, Bruce Nogales
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Publication number: 20220330819Abstract: An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.Type: ApplicationFiled: June 20, 2022Publication date: October 20, 2022Inventors: Thomas W. Burns, Harold A. Heitzmann, Kenneth Martin Curry, David S. Haffner, David Applegate, Bruce Nogales
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Patent number: 11363951Abstract: An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.Type: GrantFiled: September 12, 2012Date of Patent: June 21, 2022Assignee: GLAUKOS CORPORATIONInventors: Thomas W. Burns, Harold A. Heitzmann, Kenneth Martin Curry, David S. Haffner, David Applegate, Bruce Nogales
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Publication number: 20210298948Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: March 31, 2021Publication date: September 30, 2021Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Publication number: 20210015662Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: ApplicationFiled: October 1, 2020Publication date: January 21, 2021Inventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Patent number: 10813789Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.Type: GrantFiled: June 5, 2017Date of Patent: October 27, 2020Assignee: Dose Medical CorporationInventors: David S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
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Publication number: 20190083307Abstract: Disclosed herein are drug delivery punctal implants and methods of using the implants for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The physical arrangement of drugs within the punctal plugs disclosed herein results, in several embodiments, in advantageous controlled delivery of one or more drugs to the eye of a patient.Type: ApplicationFiled: September 23, 2016Publication date: March 21, 2019Inventors: Thomas W. BURNS, Bruce NOGALES, David APPLEGATE, Dave POWER
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Publication number: 20190053704Abstract: An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features.Type: ApplicationFiled: July 11, 2018Publication date: February 21, 2019Inventors: Thomas W. Burns, Harold A. Heitzmann, Kenneth Martin Curry, David S. Haffner, David Applegate, Bruce Nogales