Patents by Inventor David Archer Ellis

David Archer Ellis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azetidinyl Pyrimidines and Uses Thereof
    Publication number: 20240002392
    Abstract: Provided herein are compounds useful as inhibitors of Janus kinase (JAK) proteins and in treating JAK-related diseases.
    Type: Application
    Filed: June 29, 2023
    Publication date: January 4, 2024
    Inventors: David Archer Ellis, Heeren M. Gordhan, Cynthia L. Lichorowic, Jill M. Sturdivant, Mitchell A. deLong
  • Prostaglandin conjugates and derivatives for treating glaucoma and ocular hypertension
    Patent number: 10016441
    Abstract: Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma and elevated intraocular pressure are disclosed. Such compositions comprise an effective amount of prostaglandin conjugates or derivatives of the present invention.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: July 10, 2018
    Assignee: NOVARTIS AG
    Inventors: David Archer Ellis, Lukas Scheibler, Najam A. Sharif
  • PROSTAGLANDIN CONJUGATES AND DERIVATIVES FOR TREATING GLAUCOMA AND OCULAR HYPERTENSION
    Publication number: 20170239268
    Abstract: Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma and elevated intraocular pressure are disclosed. Such compositions comprise an effective amount of prostaglandin conjugates or derivatives of the present invention.
    Type: Application
    Filed: March 3, 2017
    Publication date: August 24, 2017
    Inventors: David Archer Ellis, Lukas Scheibler, Najam A. Sharif
  • Prostaglandin conjugates and derivatives for treating glaucoma and ocular hypertension
    Patent number: 9604949
    Abstract: Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma and elevated intraocular pressure are disclosed. Such compositions comprise an effective amount of prostaglandin conjugates or derivatives of the present invention.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: March 28, 2017
    Assignee: Novartis AG
    Inventors: David Archer Ellis, Lukas Scheibler, Najam A. Sharif
  • Azolopyrimidines as inhibitors of cannabinoid 1 activity
    Patent number: 8722691
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: May 13, 2014
    Assignee: IRM LLC
    Inventors: Xiaohui He, Kunyong Yang, Hong Liu, David Archer Ellis
  • COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS
    Publication number: 20130345220
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
    Type: Application
    Filed: August 29, 2013
    Publication date: December 26, 2013
    Applicant: IRM LLC
    Inventors: Valentina MOLTENI, Xiaolin Li, Juliet Nabakka, David Archer Ellis, Beth Anaclerio, Enrique Saez, John Wityak
  • Compounds and compositions as LXR modulators
    Patent number: 8569345
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: October 29, 2013
    Inventors: Valentina Molteni, Xiaolin Li, Juliet Nabakka, David Archer Ellis, Beth Anaclerio, Enrique Saez, John Wityak
  • COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY
    Publication number: 20120225869
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).
    Type: Application
    Filed: March 8, 2012
    Publication date: September 6, 2012
    Applicant: IRM LLC
    Inventors: Hong Liu, Xiaohui He, Ha-Soon Choi, Kunyong Yang, David H. Woodmansee, Zhicheng Wang, David Archer Ellis, Boagen Wu, Yun He, Truc Ngoc Nguyen
  • COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS
    Publication number: 20120214812
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
    Type: Application
    Filed: March 7, 2012
    Publication date: August 23, 2012
    Applicant: IRM LLC
    Inventors: VALENTINA MOLTENI, XIAOLIN LI, JULIET NABAKKA, DAVID ARCHER ELLIS, BETH ANACLERIO, ENRIQUE SAEZ, JOHN WITAK
  • Compounds and compositions as LXR modulators
    Patent number: 8158662
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: April 17, 2012
    Assignee: Hamilton
    Inventors: Valentina Molteni, Xiaolin Li, Juliet Nabakka, David Archer Ellis, Beth Anaclerio, Enrique Saez, John Wityak
  • Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
    Patent number: 8158634
    Abstract: The invention provides compounds having Formula Ia, or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and Y are as defined in the specification; as well as pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: April 17, 2012
    Assignee: IRM LLC
    Inventors: Hong Liu, Xiaohui He, Ha-Soon Choi, Kunyong Yang, David Woodmansee, Zhicheng Wang, David Archer Ellis, Baogen Wu, Yun He, Truc Ngoc Nguyen
  • Compounds and compositions as lxr modulators
    Publication number: 20090325981
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).
    Type: Application
    Filed: February 11, 2005
    Publication date: December 31, 2009
    Applicant: IRM LLC
    Inventors: Valentina Molteni, Xiaolin Li, Juliet Nabakka, David Archer Ellis, Beth Anaclerio, Enrique Saez, John Wityak
  • Pyrrolidones with anti-HIV activity
    Patent number: 7601742
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: October 13, 2009
    Assignee: IRM LLC
    Inventors: Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya
  • COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY
    Publication number: 20090247517
    Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).
    Type: Application
    Filed: October 26, 2005
    Publication date: October 1, 2009
    Inventors: Hong Liu, Xiaohui He, Ha-Soon Choi, Kunyong Yang, David H. Woodmansee, Zhicheng Wang, David Archer Ellis, Baogen Wu, Yun He, Truc Ngoc Nguyen
  • Azolopyrimidines as Inhibitors of Cannabinoid 1 Activity
    Publication number: 20090247556
    Abstract: The invention provides compounds of formula (Ia), (Ic), (Ig) and (Ik), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).
    Type: Application
    Filed: March 30, 2007
    Publication date: October 1, 2009
    Applicant: IRM LLC
    Inventors: Xiaohui He, Kunyong Yang, Hong Liu, David Archer Ellis
  • Pyrrolidones with anti-HIV activity
    Patent number: 7495016
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: February 24, 2009
    Assignee: IRM LLC
    Inventors: Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya
  • Phenyl-Substituted Pyrrolidones
    Publication number: 20080287516
    Abstract: The present invention relates to phenyl-substituted pyrrolidones and compounds related to phenyl-substituted pyrrolidones. One use of these compounds is for the inhibition of viruses, e.g., HIV. The invention further relates to methods of malting these compounds, methods of identifying the efficacy of these compounds, and methods of using these compounds to inhibit or prevent HIV infection and related disease states such as AIDS.
    Type: Application
    Filed: January 30, 2006
    Publication date: November 20, 2008
    Applicant: IRM LLC
    Inventors: Baogen Wu, Truc Ngoc Nguyen, David Archer Ellis, Xiaohui He, Beth Marie Anaclerio, Kunyong Yang, Ha-soon Choi, Zhicheng Wang, Thomas H. Marsilje, Yun He
  • PYRROLIDONES WITH ANTI-HIV ACTIVITY
    Publication number: 20080255136
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Application
    Filed: April 22, 2008
    Publication date: October 16, 2008
    Applicant: IRM LLC
    Inventors: Baogen Wu, Yun He, Truc Nguyen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya
  • Oxindoles with anti-HIV activity
    Patent number: 7205328
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: April 17, 2007
    Assignee: IRM LLC
    Inventors: Yun He, Tao Jiang, Kelli L. Kuhen, David Archer Ellis, Baogen Wu, Tom Yao-Hsiang Wu, Badry Bursulaya
  • Quinolones with anti-HIV activity
    Patent number: 7019141
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: March 28, 2006
    Assignee: IRM LLC
    Inventors: Yun He, David Archer Ellis, Beth Marie Anaclerio, Kelli L. Kuhen, Baogen Wu, Tao Jiang