Abstract: Methods, systems, and media for presenting media content previews are provided.

Abstract: The present disclosure is related to improving image quality in a scanning camera system via scan angle selection to obtain images having overlap for performing image stitching, dynamically tuning an aperture of a camera in the scanning camera system, updating pixel values of an image using vignetting data, or a combination thereof.

Abstract: An aspect relates to generation of a plurality of elements, receiving an encrypted communication of a first entity from a client requesting an element, record a transfer of the element on a distributed synchronized database to the first entity, using transferred resources to enable a first user to obtain a right in a second entity, wherein the second entity controls an object; generate a unique identifier for the first user, thereby providing enhanced anonymity and security, recording on the distributed synchronized database a certificate corresponding to the first user right, recording rules related to a transaction related to the first object, determining whether a rule is to be executed using an off-chain computer resource using a decentralized network comprising a plurality of independent nodes wherein none of the nodes has access to all of the data to be used in executing the rule thereby enhancing data security.

Abstract: Disclosed are methods and devices for analyzing the 3D spatial and temporal nucleic acid secondary, tertiary and quaternary structures with a fluorescent interrogation system.

Abstract: This disclosure is related to positioning one or more glass plates between an image sensor and lens of a camera in a scanning camera system; determining plate rotation rates and plate rotation angles based on one of characteristics of the camera, characteristics and positioning of the one or more glass plates, and relative dynamics of the camera and the object area; and rotating the one or more glass plates about one or more predetermined axes based on corresponding plate rotation rates and plate rotation angles.

Abstract: Systems and methods are provided for performing simulated phishing attacks using social engineering indicators. One or more failure indicators can be configured in a phishing email template, and each failure indicator can be assigned a description about that failure indicator through use of a markup tag. The phishing email template containing the markup tags corresponding to the failure indicators can be stored and can be used to generate a simulated phishing email in which the one or more markup tags are removed.

Abstract: An exemplary compounding method of controlling a compounding device to prepare an admixture of at least two distinct material sources can include examining material source solutions for incompatibility of the ingredients and operating a first and a second pump to prevent one of the incompatible source solutions from entering a common flow path. The processing method can detect degradation of a fluid line by evaluating one or more of calibration error rate data, cumulative volumetric flow data, or cumulative pump operation data. The processing method can also selectively transfer a first group of source solutions using the first pump, receiving pump data from one or more sensors that sense actions of the pumps, applying fluid correction factors and calculating discrete pump movements, the pump movements being indicative of an amount of source solution displacement by a pump, and operating the pumps to selectively dispense the source solution amounts according to a preparation order.

Abstract: The invention relates to a method of treating a MEK-associated tumor by administering to a subject in need thereof a therapeutically effective amount of a solid form 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione.

Abstract: A beverage brewing system which includes a container and a beverage brewing apparatus. The container may include a body portion defining a cavity containing a beverage ingredient. The body portion may be flexible so that when it is unimpeded during a beverage vend is can expand from an initial volume to a maximum volume. The beverage brewing apparatus may support the container and may include an expansion limiter that can limit the expansion of the container during the beverage vend. The beverage brewing apparatus may operate in a first mode whereby the expansion limiter does not impede the container and the container expands from the initial state to the maximum expanded state during the beverage vend. The beverage brewing apparatus may operate in a second mode whereby the expansion limiter impedes the container and prevents the container from expanding to the maximum expanded state during the beverage vend.

Abstract: A system and device operating using a welding power bus are provided. One welding power supply includes control circuitry configured to control the operation of the welding power supply and power conversion circuitry configured to convert input power to output welding power. The welding power supply also includes welding terminals configured to receive the output welding power from the power conversion circuitry and to provide the output welding power to a device that does not use the welding power for a welding operation. The control circuitry is configured to adapt the output welding power to the device.

Abstract: The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R4 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof. The invention further relates to solid forms of 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione.

Abstract: A method of tracking proximity relationships is disclosed, comprising: (a) introducing a body into a solution of bio-molecule(s), said body comprising at least two capture probes, wherein each capture probe comprises a barcode and a capture domain, and at least one capture probe is a releasable capture probe, connected to the body via at least one cleavable linker; (b) allowing at least two capture probes to bind to their respective target bio-molecule(s) via their respective capture domains; and (c) releasing the at least one releasable capture probe from the body by cleaving its at least one cleavable linker.

Abstract: A circuit breaker for an electric load includes first and second terminals; a number of first separable contacts each electrically connected between one of the first terminals and one of the second terminals; a first mechanism to open, close or trip open the first contacts; a number of second separable contacts each electrically connected in series with a corresponding one of the first contacts; a second mechanism to open or close the second contacts; a processor to cause the second mechanism to open or close the second contacts, annunciate through one of the second terminals a power circuit electrical parameter for the electric load, receive from a number of the second terminals a confirmation from or on behalf of the electric load to cause the second mechanism to close the second contacts, and determine a fault state operatively associated with current flowing through the second contacts.

Abstract: Genome whole chromosome analysis is a critical gold standard method for clinicians to study molecular lesions at single cell level in diseases and cancers. However, they suffer from low-sample-yielding, labor-intensive procedures that require subjective manual involvement of highly trained professionals. Here we disclose new devices, systems, and methods to automate, standardize, and accelerate the digital cytopathological sample and data generation with improved data quality to enable precision medicine and improve clinical practice. This disclosure describes a family of micro-fluidic devices, and accompanying methods for using said devices, to perform cytogenomic analysis on cells, nucleus, vesicles exosomes and their respective chromosomes, chromatins, nucleic acid polymers, subcellular genomic elements and any other dynamic transitional states between these forms.

Abstract: A method for establishing a campaign for a simulated phishing attack includes receiving, via a campaign manager, specification of a plurality of parameters for a campaign including at least an identifier of a campaign and identification of users to which to send the campaign, establishing, via the campaign manager, a type of exploit for the campaign and one or more types of data to collect via the type of exploit, storing, by the campaign manager, the campaign comprising the plurality of parameters, and identifying, by a simulation server, the campaign stored in the database to create a simulated phishing email, to be sent to email accounts of the users, using the plurality of parameters of the campaign, wherein the simulated phishing email is to be created to have a link to a landing page comprising the type of exploit and configured to collect the one or more types of data.

Abstract: A circuit breaker for an electric load includes first and second terminals; a number of first separable contacts each electrically connected between one of the first terminals and one of the second terminals; a first mechanism to open, close or trip open the first contacts; a number of second separable contacts each electrically connected in series with a corresponding one of the first contacts; a second mechanism to open or close the second contacts; a processor to cause the second mechanism to open or close the second contacts, annunciate through one of the second terminals a power circuit electrical parameter for the electric load, receive from a number of the second terminals a confirmation from or on behalf of the electric load to cause the second mechanism to close the second contacts, and determine a fault state operatively associated with current flowing through the second contacts.

Abstract: Disclosed are methods for generating physical maps from feature density profiles of a nucleic acid using a constriction device, and associated methods of analyzing said genomic profiles. In addition, disclosed are devices and methods for analyzing secondary, tertiary and quaternary structures on nucleic acids in spatial and temporal context of the 3-D organization of the genome in a constriction or sensor device.

Abstract: Disclosed herein are methods, compositions and systems for the interrogation of macromolecules, more particularly for preparation of isolated single macromolecules for subsequent processing of specific regions of interest within said macromolecule based on an analysis of the molecule's physical map. The disclosure is further related to the controlled segmentation of long nucleic acid parent molecules into smaller child molecules in a targeted manner such that further processing on said children may be performed with the knowledge of their origin within the parent, in a controlled environment enabled by purposefully designed microfluidic devices. Also disclosed is binding of regional specific barcodes along the length of a long nucleic acid molecule such that upon cleavage of said molecule into child molecules, the regional origin of the children can be tracked, in a controlled environment enabled by purposefully designed microfluidic devices.

Abstract: Systems and methods are provided for performing simulated phishing attacks using social engineering indicators. One or more failure indicators can be configured in a phishing email template, and each failure indicator can be assigned a description about that failure indicator through use of a markup tag. The phishing email template containing the markup tags corresponding to the failure indicators can be stored and can be used to generate a simulated phishing email in which the one or more markup tags are removed.

Abstract: The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R4 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof. The invention further relates to solid forms of 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione.