Patents by Inventor David Avnir
David Avnir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230256102Abstract: The invention generally concerns active peptide mixture and composites thereof.Type: ApplicationFiled: June 18, 2020Publication date: August 17, 2023Inventors: Zvi Hayouka, Saul Burdman, David Avnir, Barak Menagen, Aya Brill, Tal Stern Bauer, Dafna Tamir Ariel, Heli Tamir Buchnik, Shiri Topman
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Patent number: 9643168Abstract: The present invention provides a composite comprising at least one hydrophobic organic compound and a matrix of at least one metal; wherein said at least one hydrophobic compound is entrapped within said matrix, compositions comprising at least one composite and methods of its preparation.Type: GrantFiled: May 20, 2010Date of Patent: May 9, 2017Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.Inventors: David Avnir, Raed Abu-Reziq, Rachael Ben Knaz, Itzik Yosef, Guy Nesher, Gad Marom
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Patent number: 9463245Abstract: Provided is a platform for entrapment within alumina sol-gel carriers of labile biologically active materials such as proteins, therapeutic enzymes, enzymes of industrial relevance, antigens, and small molecules for achieving successful and efficient protective storage, protection from harsh environmental conditions such as heat, pH and chemicals, delivery to site and subsequent treatment and/or vaccination against diseases against which the active agents are targeted.Type: GrantFiled: May 1, 2014Date of Patent: October 11, 2016Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: David Avnir, Abraham Rutenberg, Vladimir V. Vinogradov
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Patent number: 9289402Abstract: The present invention provides composites comprising at least one bioactive agent entrapped within a matrix of at least one metal; wherein said composite controllably releases at least one of said bioactive agent and metal or ion thereof, processes for the preparation of composites of the invention, compositions and products comprising composites of the invention and various uses thereof.Type: GrantFiled: April 26, 2011Date of Patent: March 22, 2016Assignees: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., HADASSAH ACADEMIC COLLEGEInventors: David Avnir, Rachel Ben-Knaz, Rami Pedahzur
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Publication number: 20140374663Abstract: A metallic composite is disclosed including a corrodible metal and an organic material which endows the composite with resistance to corrosion.Type: ApplicationFiled: January 17, 2013Publication date: December 25, 2014Inventors: David Avnir, Guy Nesher, Gad Marom, Hanna Levy-Behar
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Publication number: 20140328907Abstract: Provided is a platform for entrapment within alumina sol-gel carriers of labile biologically active materials such as proteins, therapeutic enzymes, enzymes of industrial relevance, antigens, and small molecules for achieving successful and efficient protective storage, protection from harsh environmental conditions such as heat, pH and chemicals, delivery to site and subsequent treatment and/or vaccination against diseases against which the active agents are targeted.Type: ApplicationFiled: May 1, 2014Publication date: November 6, 2014Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: David AVNIR, Abraham RUTENBERG, Vladimir V. VINOGRADOV
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Patent number: 8449918Abstract: A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.Type: GrantFiled: September 23, 2011Date of Patent: May 28, 2013Assignee: Sol-Gel Technologies Ltd.Inventors: Noa Lapidot, Shlomo Magdassi, David Avnir, Claudi Rottman, Orit Gans, Alon Seri-Levy
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Publication number: 20130039964Abstract: The present invention provides composites comprising at least one bioactive agent entrapped within a matrix of at least one metal; wherein said composite controllably releases at least one of said bioactive agent and metal or ion thereof, processes for the preparation of composites of the invention, compositions and products comprising composites of the invention and various uses thereof.Type: ApplicationFiled: April 26, 2011Publication date: February 14, 2013Applicants: HADASSAH ACADEMIC COLLEGE, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.Inventors: David Avnir, Rachel Ben-Knaz, Rami Pedahzur
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Publication number: 20120056341Abstract: Silica nanocapsules are prepared from a nanoemulsions obtained by a phase inversion method.Type: ApplicationFiled: March 9, 2010Publication date: March 8, 2012Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.Inventors: Shlomo Magdassi, David Avnir, Liat Spernath
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Publication number: 20120015014Abstract: A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.Type: ApplicationFiled: September 23, 2011Publication date: January 19, 2012Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Noa LAPIDOT, Shlomo Magdassi, David Avnir, Claudi Rottman, Orit Gans, Alon Seri-Levy
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Patent number: 8039020Abstract: A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.Type: GrantFiled: June 18, 2010Date of Patent: October 18, 2011Assignee: Sol-Gel Technologies Ltd.Inventors: Noa Lapidot, Shlomo Magdassi, David Avnir, Claudio Rottman, Orit Gans, Alon Seri-Levy
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Publication number: 20100297724Abstract: The present invention provides a composite comprising at least one hydrophobic organic compound and a matrix of at least one metal; wherein said at least one hydrophobic compound is entrapped within said matrix, compositions comprising at least one composite and methods of its preparation.Type: ApplicationFiled: May 20, 2010Publication date: November 25, 2010Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEMInventors: David AVNIR, Raed ABU-REZIQ, Rachael BEN KNAZ, Itzik YOSEF, Guy NESHER, Gad MAROM
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Publication number: 20100255107Abstract: A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.Type: ApplicationFiled: June 18, 2010Publication date: October 7, 2010Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Noa Lapidot, Shlomo Magdassi, David Avnir, Claudio Rottman, Orit Gans, Alon Seri-Levy
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Patent number: 7758888Abstract: A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.Type: GrantFiled: October 23, 2001Date of Patent: July 20, 2010Assignee: Sol-Gel Technologies Ltd.Inventors: Noa Lapidot, Shlomo Magdassi, David Avnir, Claudio Rottman, Orit Gans, Alon Seri-Levy
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Publication number: 20100078328Abstract: A method for the co-deposition of sol-gel and one or more additives selected from a great variety of agents including monomers, oligomers, polymers, metals and others is provided. The method affords continuous films of high stability and precision. Also provided is a surface coated with a film of sol-gel and at least one additive electrodeposited according to the presently described methods.Type: ApplicationFiled: October 7, 2007Publication date: April 1, 2010Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEMInventors: Daniel Mandler, David Avnir, Ronen Shacham
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Publication number: 20090061226Abstract: Novel nanoparticles-entrapping spherical composites, composed of a metal oxide or semi-metal oxide and a hydrophobic polymer, are disclosed. The spherical composites are characterized by well-defined spherical shape, a narrow size distribution and high compatibility with various types of nanoparticles. Further disclosed are processes for preparing the nanoparticles-entrapping spherical composites and uses thereof.Type: ApplicationFiled: December 7, 2005Publication date: March 5, 2009Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWInventors: Uri Banin, David Avnir, Taleb Mokari, Hanan Sertchook
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Publication number: 20070165022Abstract: A method for automated computerized audio visual dubbing of a movie comprises (i) generating a three-dimensional head model of an actor in a movie, the head model being representative of specific facial features of the actor, and (ii) generating a three-dimensional head model of a dubber making target sounds for the actor, the dubber head model being representative of specific facial features of the dubber, as the target sounds are made. The method also comprises modifying at least a portion of the specific facial features of the actor head model according to the dubber head model such that the actor appears to be producing target sounds made by the dubber.Type: ApplicationFiled: August 1, 2006Publication date: July 19, 2007Inventors: Shmuel Peleg, Ran Cohen, David Avnir
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Patent number: 7109993Abstract: A method for automated computerized audio visual dubbing of a movie comprises (i) generating a three-dimensional head model of an actor in a movie, the head model being representative of specific facial features of the actor, and (ii) generating a three-dimensional head model of a dubber making target sounds for the actor, the dubber head model being representative of specific facial features of the dubber, as the target sounds are made. The method also comprises modifying at least a portion of the specific facial features of the actor head model according to the dubber head model such that the actor appears to be producing target sounds made by the dubber.Type: GrantFiled: October 24, 2002Date of Patent: September 19, 2006Assignee: Yissum Research Development Company of the Hebrew University of JerusalemInventors: Shmuel Peleg, Ran Cohen, David Avnir
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Publication number: 20050255989Abstract: It is provided a monolithic reactive porous support with efficiency and performance better than a particulate support used in a batch method requiring a liquid-solid separation process or a filling column method requiring a high pressure for liquid supply. In a solution containing a starting material having a reactive site, a precursor of a monolithic porous gel formed of silica, a metal oxide, or an organic-inorganic hybrid composition is reacted. Accordingly, sol-gel transformation and phase separation are induced at the same time to form a gel of the composition having continuous pores with a diameter of 100 nm or greater.Type: ApplicationFiled: August 25, 2003Publication date: November 17, 2005Applicant: KYOTO MONOTECH CO., LTDInventors: Naohiro Soga, Kazuki Nakanishi, David Avnir
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Patent number: 6797773Abstract: A versatile methodology to obtain efficient catalytic materials suitable for selective, liquid-phase oxidations of alcohols is described. Solid inorganic membranes were prepared by the sol-gel procedure by adding a solution of stable organic nitroxyl radicals at the onset of the polymerization of silicon alkoxide monomers. In this way, micro- and mesoporous materials can be obtained that axe effective and recyclable catalytic mediators for highly selective oxidations of a vast class of primary and secondary alcohols carried out with several primary oxidants. Delicate substrates such as carbohydrates and allylic alcohols can selectively be oxidized with these novel catalytic materials.Type: GrantFiled: November 15, 2000Date of Patent: September 28, 2004Assignees: Consiglio Nazionale delle Ricerche, Yissum Research Development Company of the Hebrew University of JerusalemInventors: Mario Pagliaro, David Avnir, Giulio Deganello, Jochanan Blum