Patents by Inventor David B. Bailey
David B. Bailey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220333166Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: ApplicationFiled: January 31, 2022Publication date: October 20, 2022Applicant: Integrated Nano-Technologies, Inc.Inventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Patent number: 11236382Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: GrantFiled: June 28, 2019Date of Patent: February 1, 2022Assignee: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Publication number: 20190338346Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: ApplicationFiled: June 28, 2019Publication date: November 7, 2019Applicant: Integrated Nano-Technologies, Inc.Inventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Patent number: 10378045Abstract: A disposable cartridge for preparing a nucleic acid sample including a stationary cartridge body and a cylindrical rotor rotationally mounted to the cartridge body. The cartridge body includes: (i) a cylindrical surface defining a fixed port and (ii) a syringe barrel defining a bore in fluid communication with the fixed port. When the disposable cartridge is disposed in combination with an assay system, syringe barrel is configured to receive a moveable plunger, i.e., to stroke the plunger into and out of the barrel. The rotor is seated within a cavity of the cartridge body such that a mating surface thereof slideably engages a cylindrical surface of the cavity. The rotor comprises a plurality of chambers fluidly connecting to a plurality of ports along the mating surface at different radial positions such that at least one of the chambers is fluidly connected to one of the ports by a connecting channel.Type: GrantFiled: May 4, 2017Date of Patent: August 13, 2019Assignee: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Publication number: 20170292151Abstract: A disposable cartridge for preparing a nucleic acid sample including a stationary cartridge body and a cylindrical rotor rotationally mounted to the cartridge body. The cartridge body includes: (i) a cylindrical surface defining a fixed port and (ii) a syringe barrel defining a bore in fluid communication with the fixed port. When the disposable cartridge is disposed in combination with an assay system, syringe barrel is configured to receive a moveable plunger, i.e., to stroke the plunger into and out of the barrel. The rotor is seated within a cavity of the cartridge body such that a mating surface thereof slideably engages a cylindrical surface of the cavity. The rotor comprises a plurality of chambers fluidly connecting to a plurality of ports along the mating surface at different radial positions such that at least one of the chambers is fluidly connected to one of the ports by a connecting channel.Type: ApplicationFiled: May 4, 2017Publication date: October 12, 2017Applicant: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Patent number: 9644200Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: GrantFiled: May 18, 2016Date of Patent: May 9, 2017Assignee: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Publication number: 20160326514Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: ApplicationFiled: May 18, 2016Publication date: November 10, 2016Applicant: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nathaniel E. Wescott
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Patent number: 9347086Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: GrantFiled: October 17, 2013Date of Patent: May 24, 2016Assignee: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nate Wescott
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Publication number: 20150312217Abstract: Disclosed are various embodiments that facilitate client-side encryption of form data. A network page is sent to a client. The network page includes executable encryption code configured to encrypt a form data item. The client is configured to receive the form data item via a form field of the network page. In response to receiving the form data item from the client, it is determined whether the form data item that has been received has been encrypted in the client by the executable encryption code. The form data item is then encrypted when the form data item that has been received has not been encrypted in the client by the executable encryption code. However, the form data item is not encrypted when the form data item that has been received has been encrypted in the client by the executable encryption code.Type: ApplicationFiled: June 12, 2015Publication date: October 29, 2015Inventors: Asheley S. Lee, Saffet G. Ozdemir, Christopher A. Weiss, Mark G. Madej, David B. Bailey
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Patent number: 9058603Abstract: Disclosed are various embodiments that facilitate client-side encryption of form data. A network page that includes client-side code that encrypts one or more data items using a public key is sent to the client. The data items are provided by a user in one or more form fields of the network page. The data items and one or more unencrypted data items are obtained from the client over an encrypted channel. The data items are encrypted using the public key when the data items have not been encrypted by the client-side encryption code. The data items are sent in an encrypted state to a server over an internal network. A firewall is interposed between the internal network and the server to protect the server from the internal network.Type: GrantFiled: January 4, 2011Date of Patent: June 16, 2015Assignee: Zappos IP, Inc.Inventors: Asheley S. Lee, Saffet G. Ozdemir, Christopher A. Weiss, Mark G. Madej, David B. Bailey
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Publication number: 20140099646Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing.Type: ApplicationFiled: October 17, 2013Publication date: April 10, 2014Applicant: Integrated Nano-Technologies, LLCInventors: Dennis M. Connolly, Tara Holz, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante, Nate Wescott
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Patent number: 8663918Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic entanglement particles are used to concentrate and clean the nucleic acid molecules for further testing.Type: GrantFiled: May 24, 2010Date of Patent: March 4, 2014Assignee: Integrated Nano-Technologies, Inc.Inventors: Dennis M. Connolly, Charles DeBoer, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante
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Publication number: 20140024822Abstract: A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic entanglement particles are used to concentrate and clean the nucleic acid molecules for further testing.Type: ApplicationFiled: May 24, 2010Publication date: January 23, 2014Inventors: Dennis M. Connolly, Charles DeBoer, Vera Tannous, Christopher Kilcoin, Konstantin Aptekarev, David B. Bailey, Richard S. Murante
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Patent number: 8452785Abstract: Disclosed are various embodiments for searching for items in a catalog using normalized item attributes. A range of values on a normalized scale is determined for an option for an attribute associated with a representative item. The range of values of the representative item is correlated with a first unit on a first scale of item classification. Multiple items are identified based at least in part on the option for the attribute. Each of the items is associated with a respective option for the attribute that has a respective range of values on the normalized scale that overlaps the range of values of the representative item. The respective range of values of one or more of the items is correlated with a second unit on a second scale of item classification.Type: GrantFiled: August 13, 2010Date of Patent: May 28, 2013Assignee: Amazon Technologies, Inc.Inventors: Akiyoshi D. Iida, David B. Bailey, Jonathan R. Jacobs
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Patent number: 8313887Abstract: Flexographic printing plates and other relief images can be formed from a laser-ablatable element having a laser-ablatable layer that is from about 300 to about 4,000 ?m thickness. The laser-ablatable layer includes a film-forming material that is a laser-laser-ablatable material or the film-forming material has dispersed therein a laser-ablatable material. The laser-ablatable material is a polymeric material that when heated to 300° C. at a rate of 10° C./minute, loses at least 60% of its mass to form at least one predominant low molecular weight product. The laser-ablatable material also comprises at least 0.01 weight % of a depolymerization catalyst that is a Lewis acid or organometallic based catalyst. The element can be imaged by ablation at an energy of at least 1 J/cm2 to provide a relief image.Type: GrantFiled: December 14, 2011Date of Patent: November 20, 2012Assignee: Eastman Kodak CompanyInventors: Michael T. Regan, David B. Bailey, Christine J. Landry-Coltrain
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Patent number: 8219453Abstract: Disclosed are various embodiments for generating classifications for items from normalized item attributes. Multiple attribute options are maintained for an item. Each of the attribute options is associated with a respective range of values on a normalized scale for an attribute. Multiple item classifications are generated for one of the attribute options by mapping the respective range of values for the one of the attribute options to one or more item classifications on each of multiple scales of classification for the attribute.Type: GrantFiled: August 13, 2010Date of Patent: July 10, 2012Assignee: Amazon Technologies, Inc.Inventors: Akiyoshi D. Iida, David B. Bailey, Jonathan R. Jacobs
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Publication number: 20120160120Abstract: Relief images can be formed from a laser-ablatable element having a laser-ablatable layer that is from about 300 to about 4,000 ?m in thickness. The laser-ablatable layer includes a film-forming material that is a laser-laser-ablatable material or the film-forming material has dispersed therein a laser-ablatable material. The laser-ablatable material is a polymeric material that when heated to 300° C. at a rate of 10° C./minute, loses at least 60% of its mass to form at least one predominant low molecular weight product. The laser-ablatable material can also comprise at least 0.01 weight % of a depolymerization catalyst that is a Lewis acid or organometallic based catalyst. The element can be imaged by ablation at an energy of at least 1 J/cm2 to provide a relief image.Type: ApplicationFiled: March 2, 2012Publication date: June 28, 2012Inventors: Michael T. Regan, David B. Bailey, Christine J. Landry-Coltrain
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Patent number: 8187794Abstract: Flexographic printing plates and other relief images can be formed from a laser-ablatable element having a laser-ablatable layer that is at least 20 ?m in thickness. The laser-ablatable layer includes a film-forming material that is a laser-laser-ablatable material or the film-forming material has dispersed therein a laser-ablatable material. The laser-ablatable material is a polymeric material that when heated to 300° C. at a rate of 10° C./minute, loses at least 60% of its mass to form at least one predominant low molecular weight product. The element can be imaged by ablation at an energy of at least 1 J/cm2 to provide a relief image.Type: GrantFiled: July 25, 2007Date of Patent: May 29, 2012Assignee: Eastman Kodak CompanyInventors: Michael T. Regan, David B. Bailey, Christine J. Landry-Coltrain
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Patent number: 8187793Abstract: Flexographic printing plates and other relief images can be formed from a laser-ablatable element having a laser-ablatable layer that is at least 20 ?m in thickness. The laser-ablatable layer includes a film-forming material that is a laser-laser-ablatable material or the film-forming material has dispersed therein a laser-ablatable material. The laser-ablatable material is a polymeric material that when heated to 300° C. at a rate of 10° C./minute, loses at least 60% of its mass to form at least one predominant low molecular weight product. The element can be imaged by ablation at an energy of at least 1 J/cm2 to provide a relief image.Type: GrantFiled: April 23, 2007Date of Patent: May 29, 2012Assignee: Eastman Kodak CompanyInventors: Michael T. Regan, David B. Bailey, Christine J. Landry-Coltrain
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Patent number: 8163465Abstract: Flexographic printing plates and other relief images can be formed from a laser-ablatable element having a laser-ablatable layer that is from about 300 to about 4,000 ?m in thickness. The laser-ablatable layer includes a film-forming material that is a laser-laser-ablatable material or the film-forming material has dispersed therein a laser-ablatable material. The laser-ablatable material is a polymeric material that when heated to 300° C. at a rate of 10° C./minute, loses at least 60% of its mass to form at least one predominant low molecular weight product. The laser-ablatable material also comprises at least 0.01 weight % of a depolymerization catalyst that is a Lewis acid or organometallic based catalyst. The element can be imaged by ablation at an energy of at least 1 J/cm2 to provide a relief image.Type: GrantFiled: July 19, 2010Date of Patent: April 24, 2012Assignee: Eastman Kodak CompanyInventors: Michael T. Regan, David B. Bailey, Christine J. Landry-Coltrain