Patents by Inventor David B. Capps

David B. Capps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
    Patent number: 4626540
    Abstract: Substituted 1-amino-4-nitroacridinones, their method of manufacture, pharmaceutical compositions and their use as antibacterial and antitumor agents are herein described.
    Type: Grant
    Filed: October 10, 1984
    Date of Patent: December 2, 1986
    Assignee: Warner-Lambert Company
    Inventor: David B. Capps
  • Method of treating leukemia with pyrazolo[3,4,5-kl]acridines
    Patent number: 4621086
    Abstract: Pyrazolo[3,4,5-kl]acridines are described as antibacterial agents and antitumor agents as well as pharmaceutical compositions and methods for their preparation.
    Type: Grant
    Filed: January 22, 1986
    Date of Patent: November 4, 1986
    Assignee: Warner-Lambert Company
    Inventor: David B. Capps
  • Antibacterial benzo(chalcogeno)[4,3,2-cd]indazoles
    Patent number: 4604390
    Abstract: Substituted 2H-[1]benzopyrano[4,3,2-cd]indazoles, 2H-[1]benzothiopyrano[4,3,2-cd]indazoles, and 2H-[1]benzoselenino[4,3,2-cd]indazoles have demonstrated pharmacological activity against a broad spectrum of Gram-positive and Gram-negative bacteria, yeasts, and fungi, as well as activity against the L1210 and P388 murine leukemia cells lines.Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating bacterial or fungal infections and of inhibiting the growth of neoplasms in mammals are also disclosed.
    Type: Grant
    Filed: May 24, 1985
    Date of Patent: August 5, 1986
    Assignee: Warner-Lambert Company
    Inventors: Edward F. Elslager, Leslie M. Werbel, Daniel F. Ortwine, Donald F. Worth, Howard D. H. Showalter, David B. Capps, Ellen M. Berman, Vlad E. Gregor, Anthony D. Sercel
  • Pyrazolo[3,4,5-k1]acridine compositions and methods for their use as antimicrobials
    Patent number: 4588730
    Abstract: Pyrazolo[3,4,5-k1]acridines are described as antibacterial agents and antitumor agents as well as pharmaceutical compositions and methods for their preparation.
    Type: Grant
    Filed: August 22, 1985
    Date of Patent: May 13, 1986
    Assignee: Warner-Lambert Company
    Inventor: David B. Capps
  • Pyrazolo[3,4,5-kl]acridine compositions and methods for their production and use
    Patent number: 4555572
    Abstract: Pyrazolo[3,4,5-kl]acridines are described as antibacterial agents and antitumor agents as well as pharmaceutical compositions and methods for their preparation.
    Type: Grant
    Filed: June 15, 1984
    Date of Patent: November 26, 1985
    Assignee: Warner-Lambert Company
    Inventor: David B. Capps
  • Amino-substituted imidazo[1,2-a:3,4-a']diquinolin-15-ium salts compositions and method of use
    Patent number: 4207320
    Abstract: Amino-substituted imidazo[1,2-a:3,4-a']diquinolin-15-ium salts having the formula I: ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, C.sub.4 -C.sub.6 cycloalkyl, di(lower alkyl)amino, 1-azetidinyl, 1-pyrrolidinyl, 1-piperidinyl, methyl-1-pyrrolidinyl, methyl-1-piperidinyl, 4-morpholinyl or 2,2-dimethylhydrazino;R.sub.2 is hydrogen, lower alkyl, lower alkylamino, di(lower alkyl)amino, C.sub.4 -C.sub.6 cycloalkylamino, lower alkoxy(lower alkyl)amino, 1-azetidinyl, 1-pyrrolidinyl, 1-piperidinyl, methyl-1-pyrrolidinyl, methyl-1-piperidinyl, hexahydro-1H-azepin-1-yl, 4-morpholinyl, benzylamino, N-methylbenzylamino or 2-phenylethylamino;R.sub.3 is hydrogen or methyl;X is an anion;with the proviso that at least one of R.sub.1 and R.sub.2 is other than hydrogen, lower alkyl or C.sub.4 -C.sub.6 cycloalkyl; and with the further proviso that when R.sub.2 is dimethylamino, at least one of R.sub.1 and R.sub.3 is other than hydrogen, and intermediates used in the preparation thereof are disclosed.
    Type: Grant
    Filed: August 28, 1978
    Date of Patent: June 10, 1980
    Assignee: Warner-Lambert Company
    Inventors: David B. Capps, Mario M. Angelo, Townley P. Culbertson