Patents by Inventor David B. Collinge

David B. Collinge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing the sesquiterpene viridiflorol with a fungal enzyme
    Patent number: 12415997
    Abstract: Constructs, host cells, fungi, seeds, plants, and methods are described herein can include a Serendipita indica terpenoid synthase (SiTPS). Such constructs host cells, fungi, seeds, plants, and methods are useful, for example, for making viridiflorol. As described herein, the basidionycete Serendipita indica, a non-specific-host root endophyte fungus, possesses a functional terpenoid synthase gene (SiTPS). Heterologous expression of SiTPS in host cells showed that the produced protein efficiently utilizes the fifteen-carbon precursor farnesylpyrophosphate (FTP) to synthesize the sesquiterpene alcohol viridiflorol, shown below.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: September 16, 2025
    Assignees: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY, UNIVERSITY OF COPENHAGEN
    Inventors: Fani Ntana, David B. Collinge, Björn Hamberger, Wajid Waheed Bhat, Sean Johnson, Birgit Jensen, Hans Jorgen Lyngs Jorgensen
  • METHOD FOR PRODUCING THE SESQUITERPENE VIRIDIFLOROL WITH A FUNGAL ENZYME
    Publication number: 20230002797
    Abstract: Constructs, host cells, fungi, seeds, plants, and methods are described herein can include a Serendipita indica terpenoid synthase (SiTPS). Such constructs host cells, fungi, seeds, plants, and methods are useful, for example, for making viridiflorol. As described herein, the basidionycete Serendipita indica, a non-specific-host root endophyte fungus, possesses a functional terpenoid synthase gene (SiTPS). Heterologous expression of SiTPS in host cells showed that the produced protein efficiently utilizes the fifteen-carbon precursor farnesylpyrophosphate (FTP) to synthesize the sesquiterpene alcohol viridiflorol, shown below.
    Type: Application
    Filed: September 11, 2020
    Publication date: January 5, 2023
    Inventors: Fani Ntana, David B. Collinge, Björn Hamberger, Wajid Waheed Bhat, Sean Johnson, Birgit Jensen, Hans Jorgen Lyngs Jorgensen