Patents by Inventor David B. Guthrie

David B. Guthrie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20220235092
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: February 4, 2022
    Publication date: July 28, 2022
    Applicant: EMORY UNIVERSITY
    Inventors: David B. Guthrie, Mark A. Lockwood, Dennis C. Liotta, Michael G. Natchus, Donald G. Stein, Iqbal Sayeed
  • Progesterone analogs and uses related thereto
    Patent number: 11274118
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: March 15, 2022
    Assignee: EMORY UNIVERSITY
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed
  • N4-hydroxycytidine and derivatives and anti-viral uses related thereto
    Patent number: 10874683
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of a Zika virus infection.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: December 29, 2020
    Assignee: Emory University
    Inventors: George R. Painter, David B. Guthrie, Gregory R. Bluemling, Michael R. Natchus
  • Steroid analogues for neuroprotection
    Patent number: 10716795
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: July 21, 2020
    Assignee: Emory University
    Inventors: Christopher MacNevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20190276489
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: May 23, 2019
    Publication date: September 12, 2019
    Inventors: David B. Guthrie, Mark A. Lockwood, Dennis C. Liotta, Michael G. Natchus, Donald G. Stein, Iqbal Sayeed
  • Progesterone analogs and uses related thereto
    Patent number: 10336787
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: July 2, 2019
    Assignee: Emory University
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed
  • N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto
    Publication number: 20190083520
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of a Zika virus infection.
    Type: Application
    Filed: March 10, 2017
    Publication date: March 21, 2019
    Inventors: George R. Painter, David B. Guthrie, Gregory R. Bluemling, Michael R. Natchus
  • Steroid Analogues for Neuroprotection
    Publication number: 20180221390
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Application
    Filed: April 4, 2018
    Publication date: August 9, 2018
    Inventors: Christopher MacNevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • Steroid Analogues for Neuroprotection
    Publication number: 20170065615
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Application
    Filed: November 18, 2016
    Publication date: March 9, 2017
    Inventors: Christopher MacNevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • Steroid analogues for neuroprotection
    Patent number: 9527881
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: December 27, 2016
    Assignee: Emory University
    Inventors: Christopher Macnevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20160052957
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: November 4, 2015
    Publication date: February 25, 2016
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed
  • STEROID ANALOGUES FOR NEUROPROTECTION
    Publication number: 20110263553
    Abstract: Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
    Type: Application
    Filed: February 26, 2009
    Publication date: October 27, 2011
    Inventors: Christopher Macnevin, Donald G. Stein, Dennis C. Liotta, Iqbal Sayeed, David B. Guthrie, Mark A. Lockwood, Michael G. Natchus
  • Zinc oxide dispersions by decomposition of zinc acetate
    Patent number: 4410446
    Abstract: This invention relates to stable, fluid zinc-containing dispersions and the preparations thereof by the high temperature decomposition of zinc acetate to ZnO in a dispersant-containing fluid, said dispersant being stable at the temperature of decomposition.
    Type: Grant
    Filed: June 7, 1979
    Date of Patent: October 18, 1983
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie
  • Low temperature process of preparing Mg(OH).sub.2 suspensions
    Patent number: 4298482
    Abstract: This invention relates to a process of preparing stable suspensions of Mg(OH).sub.2 which comprises blending Mg(OH).sub.2 powder with acid in a surfactant-containing fluid to effect particle size reduction of the starting Mg(OH).sub.2 powder. In practice, the mole-fraction of acid employed is less than 50% of that stoichiometrically necessary for the formation of the magnesium salt.
    Type: Grant
    Filed: June 20, 1979
    Date of Patent: November 3, 1981
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie
  • MgO Dispensions
    Patent number: 4293429
    Abstract: This invention relates to a stable, fluid magnesium oxide-containing dispersion prepared by the thermal treatment of MgO powder in a non-volatile fluid in the presence of a stoichiometric or lesser amount of a carboxylic acid as illustrated by acetic acid.
    Type: Grant
    Filed: January 16, 1980
    Date of Patent: October 6, 1981
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie, Donald M. Leiendecker
  • Magnesium-containing dispersions
    Patent number: 4229309
    Abstract: This invention relates to stable, fluid magnesium-containing dispersions and the preparations thereof by the high temperature dehydration of Mg(OH).sub.2 to MgO in a dispersant-containing fluid.
    Type: Grant
    Filed: July 18, 1977
    Date of Patent: October 21, 1980
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie
  • Magnesium-containing dispersions by decomposition of MgCO.sub.3
    Patent number: 4226739
    Abstract: This invention relates to stable, fluid magnesium-containing dispersions and the preparations thereof by the high temperature decomposition of MgCO.sub.3 to MgO in a dispersant-containing fluid.
    Type: Grant
    Filed: March 10, 1978
    Date of Patent: October 7, 1980
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie
  • ZnO dispersions by decomposition of ZnCO.sub.3
    Patent number: 4193769
    Abstract: This invention relates to stable, fluid zinc-containing dispersions and the preparations thereof by the high temperature decomposition of ZnCO.sub.3 to ZnO in a dispersant-containing fluid.
    Type: Grant
    Filed: October 23, 1978
    Date of Patent: March 18, 1980
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie
  • Preparation of magnesium-containing dispersions from magnesium carboxylates
    Patent number: 4179383
    Abstract: This invention relates to stable, fluid magnesium-containing dispersions and the preparations thereof by the high temperature decomposition of Magnesium salts of carboxylic acids to MgO in a dispersant-containing fluid.
    Type: Grant
    Filed: October 7, 1977
    Date of Patent: December 18, 1979
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie
  • CaCO.sub.3 -containing dispersions
    Patent number: 4164472
    Abstract: This invention relates to stable, fluid CaCO.sub.3 -containing dispersions, and the preparations thereof by the high temperature decomposition of a Ca carboxylate such as Ca acetate, etc., in a dispersant-containing fluid.
    Type: Grant
    Filed: April 10, 1978
    Date of Patent: August 14, 1979
    Assignee: Petrolite Corporation
    Inventors: William J. Cheng, David B. Guthrie