Patents by Inventor David B. Haslam

David B. Haslam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule inhibition of intracellular transport
    Patent number: 8278321
    Abstract: The present disclosure characterizes the activity of Golgicide A (GCA), as a potent, specific and reversible small molecule inhibitor of Golgi BFA resistance factor 1 (GBF1) function. A mutant GBF1 gene that is resistant to GCA is also described. Methods of using GCA and the GCA-resistant GBF1 gene are described including methods for modulating GBF1 activity for research and therapeutic purposes. Also described are compositions incorporating a GCA-resistant GBF1.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: October 2, 2012
    Assignee: Washington University
    Inventor: David B. Haslam
  • SMALL MOLECULE INHIBITION OF INTRACELLULAR TRANSPORT
    Publication number: 20100159468
    Abstract: The present disclosure characterizes the activity of Golgicide A (GCA), as a potent, specific and reversible small molecule inhibitor of Golgi BFA resistance factor 1 (GBF1) function. A mutant GBF1 gene that is resistant to GCA is also described. Methods of using GCA and the GCA-resistant GBF1 gene are described including methods for modulating GBF1 activity for research and therapeutic purposes. Also described are compositions incorporating a GCA-resistant GBF1.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 24, 2010
    Applicant: THE WASHINGTON UNIVERSITY
    Inventor: David B. Haslam