Patents by Inventor David B. Powers
David B. Powers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200085996Abstract: A method of stabilizing a craniomaxillofacial fracture includes heating a resorbable material to make the resorbable material flowable; applying the flowable resorbable material to a portion of a first bone fragment defining a fracture; and bonding the portion of the first bone fragment to an adjacent second bone fragment to stabilize the first bone fragment relative to the second bone fragment; wherein the first bone fragment is stabilized relative to the second bone fragment without an external force being applied directly to either the first bone fragment or the second bone fragment.Type: ApplicationFiled: May 23, 2018Publication date: March 19, 2020Inventor: David B. Powers
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Patent number: 9315573Abstract: The present disclosure relates to antibodies directed to the tumor necrosis factor alpha (“TNF-?”) and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of TNF-?.Type: GrantFiled: February 28, 2014Date of Patent: April 19, 2016Assignee: AbbVie Biotherapeutics Inc.Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers
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Patent number: 9079953Abstract: The present disclosure relates to antibodies directed to vascular endothelial growth factor (“VEGF”) and uses of such antibodies, for example to treat diseases associated with the activity and/or overproduction of VEGF.Type: GrantFiled: June 17, 2010Date of Patent: July 14, 2015Assignee: AbbVie Biotherapeutics Inc.Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. DuBridge, David B. Powers
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Patent number: 8937159Abstract: The present disclosure relates to antibodies directed to HER2 and uses of such antibodies, for example to treat diseases associated with the activity and/or overproduction of HER2.Type: GrantFiled: December 15, 2010Date of Patent: January 20, 2015Assignee: AbbVie Biotherapeutics Inc.Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers
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Publication number: 20140212424Abstract: The present disclosure relates to antibodies directed to the tumor necrosis factor alpha (“TNF-?”) and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of TNF-?.Type: ApplicationFiled: February 28, 2014Publication date: July 31, 2014Applicant: AbbVie Biotherapeutics Inc.Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers
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Patent number: 8722860Abstract: The present disclosure relates to antibodies directed to the tumor necrosis factor alpha (“TNF-?”) and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of TNF-?.Type: GrantFiled: April 16, 2010Date of Patent: May 13, 2014Assignee: AbbVie Biotherapeutics Inc.Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers
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Patent number: 8658175Abstract: The present invention relates to antibodies directed to EGFR and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of EGFR.Type: GrantFiled: October 28, 2010Date of Patent: February 25, 2014Assignee: AbbVie Biotherapeutics Inc.Inventors: Robert B. Dubridge, David B. Powers, Charles M. Forsyth
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Patent number: 8461306Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: June 11, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Patent number: 8444980Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: May 21, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Patent number: 8436146Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: May 7, 2013Assignee: AbbVie Biotherapeutics Inc.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Patent number: 8349330Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: GrantFiled: July 1, 2011Date of Patent: January 8, 2013Assignee: Abbott Biotherapeutics Corp.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120135005Abstract: The present disclosure relates to antibodies directed to the tumor necrosis factor alpha (“TNF-?”) and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of TNF-?.Type: ApplicationFiled: April 16, 2010Publication date: May 31, 2012Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers
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Publication number: 20120070440Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 22, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120064067Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 15, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20120064069Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 15, 2012Applicant: ABBOTT BIOTHERAPEUTICS CORP.Inventors: Marna WILLIAMS, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Llu
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Publication number: 20120064068Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.Type: ApplicationFiled: July 1, 2011Publication date: March 15, 2012Applicant: Abbott Biotherapeutics Corp.Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Gao Liu
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Publication number: 20110177095Abstract: The present disclosure relates to antibodies directed to HER2 and uses of such antibodies, for example to treat diseases associated with the activity and/or overproduction of HER2.Type: ApplicationFiled: December 15, 2010Publication date: July 21, 2011Applicant: Abbott Biotherapeutics CorporationInventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers
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Publication number: 20110117110Abstract: The present invention relates to antibodies directed to EGFR and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of EGFR.Type: ApplicationFiled: October 28, 2010Publication date: May 19, 2011Applicant: Facet Biotech CorporationInventors: Yoshiko AKAMATSU, Robert B. Dubridge, David B. Powers
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Publication number: 20100322931Abstract: The present disclosure relates to antibodies directed to vascular endothelial growth factor (“VEGF”) and uses of such antibodies, for example to treat diseases associated with the activity and/or overproduction of VEGF.Type: ApplicationFiled: June 17, 2010Publication date: December 23, 2010Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. DuBridge, David B. Powers
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Publication number: 20100266613Abstract: The present invention relates to antibodies directed to the tumor necrosis factor alpha (“TNF-?”) and uses of such antibodies, for example to treat diseases associated with the activity and/or overproduction of TNF-?.Type: ApplicationFiled: April 16, 2010Publication date: October 21, 2010Inventors: Fiona A. Harding, Yoshiko Akamatsu, Robert B. Dubridge, David B. Powers