Patents by Inventor David B. Seligson

David B. Seligson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HISTONE MODIFICATION PATTERNS FOR CLINICAL DIAGNOSIS AND PROGNOSIS OF CANCER
    Publication number: 20120094949
    Abstract: The present invention provides methods of diagnosing and providing a prognosis and therapy for cancer including, but not limited to, pancreatic cancer and responsiveness to thymidylate synthase inhibitor (e.g., 5-FU) therapy, by identifying cancers with altered histone modification patterns selected from the group consisting of H3K4me2, H3K9me2, or H3K18ac.
    Type: Application
    Filed: April 14, 2010
    Publication date: April 19, 2012
    Applicant: The Regents of the University of California
    Inventors: David W. Dawson, Siavash K. Kurdistani, David B. Seligson
  • AROMATASE EXPRESSION PREDICTS SURVIVAL IN WOMEN WITH NON-SMALL CELL LUNG CANCER
    Publication number: 20100331203
    Abstract: The present invention relates to the discovery that the level of aromatase polypeptide expression in non-small cell lung carcinomas can be used for example to provide information useful in prognostic and therapeutic methodologies in women having or suspected of having this cancer.
    Type: Application
    Filed: October 6, 2008
    Publication date: December 30, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Lee Goodglick, Richard J. Pietras, Vei Mah, David B. Seligson, David S. Chia, Diana C. Marquez-Garban, Michael C. Fishbein
  • Antibodies Against Histone Modifications for Clinical Diagnosis and Prognosis of Cancer
    Publication number: 20080248039
    Abstract: The present invention provides methods of diagnosing and providing a prognosis for a cancer by identifying cancers with altered global histone modification patterns using immunohistochemical techniques.
    Type: Application
    Filed: May 1, 2006
    Publication date: October 9, 2008
    Applicant: The Regents of the University of California
    Inventors: Siavash K. Kurdistani, Michael Grunstein, David B. Seligson
  • Method of isolating and purifying nucleic acids from biological samples
    Patent number: 4935342
    Abstract: The method of this invention is applicable to rapid separation, isolation, and purification of DNA or RNA from biological samples. The DNA/RNA may be in double-stranded or single-stranded form. The method is particularly advantageous for resolving genetic DNA or RNA found in bacteria, virus, and mammalian cells, and for use with samples of human bodily fluids and tissues, including stool, sputum, urine, and blood samples. DNA or RNA can be separated effectively from interfering components, particularly proteins, biological pigments and mucopolysaccharides. The method of the present invention can utilize commercially available strong or weak anion exchanger materials with selected solutions of known ionic strength for adsorption and elution.
    Type: Grant
    Filed: December 1, 1986
    Date of Patent: June 19, 1990
    Assignee: Syngene, Inc.
    Inventors: David B. Seligson, Elsie J. Shrawder