Abstract: Methods, apparatuses, and systems for detecting and classifying individual airborne biological and non-biological particles, in real time, based on particle size and polarized elastic scatter. Auto-fluorescence content may also be used along with particle size and polarized elastic scatter for further orthogonal classification. With polarized elastic scattering, the degree of linear or circular depolarization produced from particle morphology, refractive index, internal asymmetric structures and molecular optical activity can be used for classifying individual airborne particles. Alternatively, circular intensity differential scattering (CIDS) or linear intensity differential scattering (LIDS) can be used to discriminate individual particles.

Abstract: Methods, apparatuses, and systems for detecting and classifying individual airborne biological and non-biological particles, in real time, based on particle size and polarized elastic scatter. Auto-fluorescence content may also be used along with particle size and polarized elastic scatter for further orthogonal classification. With polarized elastic scattering, the degree of linear or circular depolarization produced from particle morphology, refractive index, internal asymmetric structures and molecular optical activity can be used for classifying individual airborne particles. Alternatively, circular intensity differential scattering (CIDS) or linear intensity differential scattering (LIDS) can be used to discriminate individual particles.

Abstract: A test unit having a light source (e.g., a laser) for illuminating an aerosol sample directed into a test chamber and a removable insert for the test unit. The test unit includes at least one detector for detecting the effect of the aerosol sample on light, i.e., the detector detects at least one property of light after the light has illuminated the aerosol sample. The removable insert may take a number of different forms. For example, the removable insert can form at least a portion of an unsealed or sealed test chamber when installed in an operating position. Further, the removable insert may include a removable support and at least one film or collection substance connected or applied to the removable support. The at least one film could be a filter or a non-filter. The filter could be a polarization filter (i.e., horizontal or vertical) or a fluorescence filter.

Abstract: Methods, apparatuses, and systems for detecting and classifying individual airborne biological and non-biological particles, in real time, based on particle size and polarized elastic scatter. Auto-fluorescence content may also be used along with particle size and polarized elastic scatter for further orthogonal classification. With polarized elastic scattering, the degree of linear or circular depolarization produced from particle morphology, refractive index, internal asymmetric structures and molecular optical activity can be used for classifying individual airborne particles. Alternatively, circular intensity differential scattering (CIDS) or linear intensity differential scattering (LIDS) can be used to discriminate individual particles.

Abstract: Methods, apparatuses, and systems for detecting and classifying individual airborne biological and non-biological particles, in real time, based on particle size and polarized elastic scatter. Auto-fluorescence content may also be used along with particle size and polarized elastic scatter for further orthogonal classification. With polarized elastic scattering, the degree of linear or circular depolarization produced from particle morphology, refractive index, internal asymmetric structures and molecular optical activity can be used for classifying individual airborne particles. Alternatively, circular intensity differential scattering (CIDS) or linear intensity differential scattering (LIDS) can be used to discriminate individual particles.

Abstract: A test unit having a light source (e.g., a laser) for illuminating an aerosol sample directed into a test chamber and a removable insert for the test unit. The test unit includes at least one detector for detecting the effect of the aerosol sample on light, i.e., the detector detects at least one property of light after the light has illuminated the aerosol sample. The removable insert may take a number of different forms. For example, the removable insert can form at least a portion of an unsealed or sealed test chamber when installed in an operating position. Further, the removable insert may include a removable support and at least one film or collection substance connected or applied to the removable support. The at least one film could be a filter or a non-filter. The filter could be a polarization filter (i.e., horizontal or vertical) or a fluorescence filter.

Abstract: A method and apparatus is disclosed for detecting, classifying and identifying airborne and non-airborne particles on an individual basis in substantially real time by directing a particle stream to react with optical reporters and markers and then exposing the stream to an excitation source such that individual particles have their multiple identifying characteristics detected.

Abstract: A method and device are disclosed for continuously detecting, classifying and identifying toxic particles, aerosols and/or vapor in an air sample, in near real time by directing an air sample containing an optional target analyte, in the form of particles, aerosols and/or vapors, enzyme(s), and enzyme substrate(s), to a surface of a collection matrix for forming a biocatalytic reaction product of a plurality of freely mobile optical reporters, and by using a light source with optical reader to interpret the signal from the optical reporter, enabling the detection, classification and identification of toxic particles, aerosols and/or vapor in the air sample.

Abstract: A method and device are disclosed for continuously detecting, classifying and identifying toxic particles, aerosols and/or vapor in an air sample, in near real time by directing an air sample containing an optional target analyte, in the form of particles, aerosols and/or vapors, enzyme(s), and enzyme substrate(s), to a surface of a collection matrix for forming a biocatalytic reaction product of a plurality of freely mobile optical reporters, and by using a light source with optical reader to interpret the signal from the optical reporter, enabling the detection, classification and identification of toxic particles, aerosols and/or vapor in the air sample.

Abstract: Enhanced methods, apparatuses and systems are disclosed for the real-time detection and classification of biological and non-biological particles by substantially simultaneously measuring a single particle's characteristics in terms of size and density, elastic scattering properties, and absorption and fluorescence.

Abstract: A continuous wave laser excites a biological particle. Detection channels are created to detect light scattered by the biological particle, and to detect any auto-fluorescence emitted by the biological particle. Additional channels can also detect light emitted by auto-fluorescence of the biological particle when simultaneously excited by light at harmonics of the laser's fundamental wavelength. The biological particle is identified using Mie scattering and auto-fluorescence. Ratio-metric calculations generated by calculating ratios of detected peak heights or integrated pulse values in the channels provides additional information for identifying and classifying the biological particle. A warning or alert can be provided if the identified biological particle is a particle of interest.

Abstract: A continuous wave laser excites a biological particle. Detection channels are created to detect light scattered by the biological particle, and to detect any auto-fluorescence emitted by the biological particle. Additional channels can also detect light emitted by auto-fluorescence of the biological particle when simultaneously excited by light at harmonics of the laser's fundamental wavelength. The biological particle is identified using Mie scattering and auto-fluorescence. Ratio-metric calculations generated by calculating ratios of detected peak heights or integrated pulse values in the channels provides additional information for identifying and classifying the biological particle. A warning or alert can be provided if the identified biological particle is a particle of interest.

Abstract: An optical agglutination assay device for detecting cocaine. The device includes a hollow reaction cell defining a generally planar liquid receiving reaction chamber having a thickness which is insufficient to diminish the intensity of a ray of light passing through an aqueous reaction system in the chamber in a first direction transversely of the plane of the latter. The device also includes a pusher assembly for delivering an aqueous agglutination reaction system and an unknown substance suspected of containing cocaine into the chamber. The agglutination system is such that agglutination is inhibited in the presence of cocaine. The device also includes an optical transmitting and receiving unit aligned with the reaction cell for measuring the intensity of light reflected from the chamber as a measure of the occurrence of agglutination in the reaction system.