Patents by Inventor David Baehr

David Baehr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chiral resolution method for producing compounds useful in the synthesis of taxanes
    Patent number: 6653501
    Abstract: A method is provided for processing a solution having optical isomers to obtain a (2R,3S) target isomer: wherein P1 is H or a hydroxyl protecting group, R1 is H, an alkyl group, an olefinic group or an aromatic group, and R2 is H or R3CO, where R3 is an alkyl group, an olefinic group, an aromatic group, an O-alkyl group, an O-olefinic group or an O-aromatic group, provided that R1 is not H when R3 is Ph and P1 is H. The method includes passing the solution through a chromatographic stationary phase, such as S,S Whelk-O, that has a greater affinity for one of the target isomer and an optical isomer thereof. A portion of the solution with the target isomer is then collected. The solution may be a racemic mixture of (±)-N-CBZ-3-phenylisoserine ethyl ester.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: November 25, 2003
    Assignee: NaPro BioTherapeutics, Inc.
    Inventors: James D. McChesney, Herbert R. Brinkman, Siead Zegar, David Baehr
  • Chiral resolution method for producing compounds useful in the synthesis of taxanes
    Publication number: 20030045743
    Abstract: A method is provided for processing a solution having optical isomers to obtain a (2R,3S) target isomer: 1
    Type: Application
    Filed: June 27, 2001
    Publication date: March 6, 2003
    Inventors: James D. McChesney, Herbert R. Brinkman, Siead Zegar, David Baehr