Abstract: A manually operated ergonomic multi-axis controller such as those used for controlling cursor position along x and y axes and for entering x, y and/or z coordinate information into a computer or the like. The housing includes a distal end portion angled with respect to the upper surface and the base of the housing to conform to the natural curvature of the human hand. The primary actuator, such as a trackball or joystick is positioned at the distal end portion. Secondary actuators are located along the sides of the housing.