Abstract: The presently disclosed subject matter relates to tumor infiltrated T cells induced by oncolytic virus (“OV-induced T cells”), methods of making and using said OV-induced T cells for an adoptive T-cell therapy. The presently disclosed subject matter further relates to oncolytic viruses and armed oncolytic viruses, methods of making and using said oncolytic viruses, as well as pharmaceutical compositions and kits comprising said oncolytic viruses.

Abstract: The present invention provides non-invasive intraoral devices and methods for the detection of intraoral acid exposure, methods of making said devices, and their use in the diagnosis of disorders such as gastro-oesophageal reflux disease (GORD).

Abstract: The present disclosure relates to safety devices and systems for light mobility vehicles. In one example, a light mobility vehicle safety system includes one or more sensors and a processor coupled to a light mobility vehicle. The processor may be configured to determine that the light mobility vehicle is part of a group of two or more light mobility vehicles; determine a position of the light mobility vehicle relative to one or more other light mobility vehicles in the group; determine one or more relevant sensors of the one or more sensors based on the position of the light mobility vehicle and positioning of the one or more sensors on the light mobility vehicle; receive first relevant safety-related data from the one or more relevant sensors; and transmit the first relevant safety-related data to one or more other light mobility vehicles in the group.

Abstract: The present disclosure relates to safety devices and systems for light mobility vehicles. In one example, a light mobility vehicle safety system includes one or more sensors and a processor coupled to a light mobility vehicle. The processor may be configured to determine that the light mobility vehicle is part of a group of two or more light mobility vehicles; determine a position of the light mobility vehicle relative to one or more other light mobility vehicles in the group; determine one or more relevant sensors of the one or more sensors based on the position of the light mobility vehicle and positioning of the one or more sensors on the light mobility vehicle; receive first relevant safety-related data from the one or more relevant sensors; and transmit the first relevant safety-related data to one or more other light mobility vehicles in the group.

Abstract: The presently disclosed subject matter relates to tumor infiltrated T cells induced by oncolytic virus (“OV-induced T cells”), methods of making and using said OV-induced T cells for an adoptive T-cell therapy. The presently disclosed subject matter further relates to oncolytic viruses and armed oncolytic viruses, methods of making and using said oncolytic viruses, as well as pharmaceutical compositions and kits comprising said oncolytic viruses.

Abstract: A method for determining orientations and positions of a plurality of electronic devices is applied for at least 3 or 4 electronic devices in an area, and comprises that each electronic device obtains angle measurements, ranging measurements and positioning measurements of the electronic device; one of the at least 3 or 4 electronic devices and/or a server collects the angle measurements, the ranging measurements and the positioning measurements of each electronic device and determines an orientation and a position of each electronic device based on the collected measurements by performing a global computation.

Abstract: The presently disclosed subject matter relates to tumor infiltrated T cells induced by oncolytic virus (“OV-induced T cells”), methods of making and using said OV-induced T cells for an adoptive T-cell therapy. The presently disclosed subject matter further relates to oncolytic viruses and armed oncolytic viruses, methods of making and using said oncolytic viruses, as well as pharmaceutical compositions and kits comprising said oncolytic viruses.

Abstract: The present disclosure relates to safety devices and systems for light mobility vehicles. In one example, a safety device for a light mobility vehicle includes a circuit board, one or more connectivity modules coupled to the circuit board, and an antenna coupled to the circuit board. The circuit board may be positioned within or coupled to a light mobility vehicle part. The antenna is configured to mitigate interference of one or more components of the light mobility vehicle part with the one or more connectivity modules.

Abstract: Methods and apparatus are disclosed for gathering raw Global Navigation Satellite Systems (GNSS) phase measurements at a GNSS receiver and making them available to a remote device for processing to calculate a position fix for the GNSS receiver. The measurements are arranged in a first subset and a second subset. First bits of the first subset and second bits of the second subset are embedded in one or more data messages for transmission to the remote device. The first bits include a coarse part and a fine part of the respective phase measurement. In contrast, the second bits describe at least a portion of the fine part, but none of the coarse part, of the respective phase measurement.

Abstract: The present disclosure relates to safety systems, devices, and methods. In one example, a safety system includes a safety device in communication with a server. The safety device includes a processing element and a connectivity module configured to receive object data from a connectivity device within a short-distance range. The processing element is configured to analyze the object data to determine one or more safety risks and to transmit one or more alerts or safe routes based on the one or more safety risks. The server is configured to receive entity data from the safety device, receive safety-related data from one or more data sources, compare the entity data to the safety-related data to determine relevant safety-related data, and transmit the relevant safety-related data to the safety device. The processing element is further configured to incorporate the relevant safety-related data into the determination of the one or more safety risks.

Abstract: Methods and apparatus are disclosed for gathering raw Global Navigation Satellite Systems (GNSS) phase measurements at a GNSS receiver and making them available to a remote device for processing to calculate a position fix for the GNSS receiver. The measurements are arranged in a first subset and a second subset. First bits of the first subset and second bits of the second subset are embedded in one or more data messages for transmission to the remote device. The first bits include a coarse part and a fine part of the respective phase measurement. In contrast, the second bits describe at least a portion of the fine part, but none of the coarse part, of the respective phase measurement.

Abstract: The present disclosure relates to a precise point positioning (PPP) method performed by a satellite navigation device. In one embodiment, the method comprises: receiving multiple positioning signals from a plurality of navigation satellites of a satellite-based navigation system using a multi-frequency receiver; receiving space segment correction data for the navigation satellites of the satellite-based navigation system; separately requesting and receiving local assistance data, wherein the local assistance data represents atmospheric errors in the vicinity of the satellite navigation device; and computing at least one of a precise position or time based on the received positioning signals, the space segment correction data and the local assistance data. The present disclosure further relates to a satellite navigation device, method for providing assistance data to at least one satellite navigation device, an assistance server, a satellite-based positioning system, and a computer program.

Abstract: The present disclosure relates to safety devices and systems for light mobility vehicles. In one example, a light mobility vehicle safety system includes one or more sensors and a processor coupled to a light mobility vehicle. The processor may be configured to determine that the light mobility vehicle is part of a group of two or more light mobility vehicles; determine a position of the light mobility vehicle relative to one or more other light mobility vehicles in the group; determine one or more relevant sensors of the one or more sensors based on the position of the light mobility vehicle and positioning of the one or more sensors on the light mobility vehicle; receive first relevant safety-related data from the one or more relevant sensors; and transmit the first relevant safety-related data to one or more other light mobility vehicles in the group.

Abstract: The present disclosure relates to a method (400) for determining a clock frequency offset between a first device having a first clock and at least one second device having at least one second clock, the method comprising: receiving (401), by the at least one second device, at least one first message from the first device, wherein information regarding a time of departure of the at least one first message is in the at least one first message; determining (402), by the at least one second device, a time of arrival of the at least one first message; receiving (403), by the at least one second device, at least one second message from the first device, wherein information regarding a time of departure of the at least one second message is in the at least one second message; determining (404), by the at least one second device, a time of arrival of the at least one second message; and determining (405) a clock frequency offset between the first clock and the at least one second clock based on the time of departure

Abstract: The disclosure relates to methods and materials for treating cancer. For example, recombinant vaccinia viruses having the ability to direct the expression of membrane-bound IL-12 polypeptides on the surface of infected cells and methods for using such recombinant vaccinia viruses to treat cancer are provided. Specifically, the disclosure provides a recombinant vaccinia virus comprising a vaccinia virus genome comprising a nucleic acid encoding an IL-12p35 polypeptide sequence and an IL-12p40 polypeptide sequence, wherein one of the polypeptide sequences comprises a membrane anchoring polypeptide sequence.

Abstract: The present invention provides non-invasive intraoral devices and methods for the detection of intraoral acid exposure, methods of making said devices, and their use in the diagnosis of disorders such as gastro-oesophageal reflux disease (GORD).

Abstract: A mold assembly includes a first upper portion, a second upper portion, and a base removably coupled to each other. A method of manufacturing an electrical connector with the mold assembly includes preheating a resin, mixing the resin with a hardener, preheating the mold assembly, injecting the resin hardener mixture into the mold assembly, and curing the resin hardener mixture.

Abstract: A mold assembly includes a first upper portion, a second upper portion, and a base removably coupled to each other. A method of manufacturing an electrical connector with the mold assembly includes preheating a resin, mixing the resin with a hardener, preheating the mold assembly, injecting the resin hardener mixture into the mold assembly, and curing the resin hardener mixture.

Abstract: The presently disclosed subject matter relates to tumor infiltrated T cells induced by oncolytic virus (“OV-induced T cells”), methods of making and using said OV-induced T cells for an adoptive T-cell therapy. The presently disclosed subject matter further relates to oncolytic viruses and armed oncolytic viruses, methods of making and using said oncolytic viruses, as well as pharmaceutical compositions and kits comprising said oncolytic viruses.

Abstract: A method is provided whereby a group of receivers local to one another make GNSS measurements of a number of satellites, from one or multiple different GNSS's, and by combining the measurements of the same satellites made by the different receivers it is possible given sufficient conditions to determine the positions of the receivers and the satellite errors such that the positions obtained are equivalent to those obtained from a traditional differential GNSS system, without the need for a static reference receiver at a known location.