Abstract: Several types of DNA cuts are used as markers of apoptosis for detection of apoptotic cells in situ. The present invention includes a method to detect DNase II type DNA damage, bearing 5?OH using vaccinia topoisomerase I. The present invention also includes a method combining a ligase-based method to detect DNase I type DNA damage and the topoisomerase based method, resulting in simultaneous detection of two specific types of DNA damage in situ.

Abstract: Several types of DNA cuts are used as markers of apoptosis for detection of apoptotic cells in situ. The present invention includes a method to detect DNase II type DNA damage, bearing 5′OH using vaccinia topoisomerase I. The present invention also includes a method combining a ligase-based method to detect DNase I type DNA damage and the topoisomerase based method, resulting in simultaneous detection of two specific types of DNA damage in situ.

Abstract: A cast simulated-stone containing flattened globules of overfilled, cured resin, which flattened globules substitute for natural stone chip additives and other such additives. The globules are formed by mixing an excess of a filler with a catalyzed liquid resin composition, the filler being added in an amount sufficient to cause the liquid to break apart into discrete, separable globules of resin composition. The globules are combined with a liquid resin composition and compressed and flattened in forming the simulated-stone.

Abstract: A method of fabricating stone-simulated articles including facings for substrates, involving roller-flattening mixtures of preferably polyester resins, curing agent, polyester-dispersed pigments, fumed silica (and other) filler and aluminum trihydrate filler into flat stone-pattern-simulating surfaces or slabs, maintaining the same sufficiently cool (as by refrigeration) to prevent curing until it is desired to use the same, and then applying to, and rolling over a substrate to be covered or faced, or otherwise forming the same into the desired article, and permitting to cure under the action of said curing agent, with the resulting product containing the stone-simulated pattern throughout.

Abstract: A cast simulated-stone containing flattened globules of overfilled, cured resin, which flattened globules substitute for natural stone chip additives and other such additives. The globules are formed by mixing an excess of a filler with a catalyzed liquid resin composition, the filler being added in an amount sufficient to cause the liquid to break apart into discrete, separable globules of resin composition. The globules are combined with a liquid resin composition and compressed and flattened in forming the simulated-stone.

Abstract: Novel artificial or simulated stone facing formed on a substrate with surface-cured finish conformance to the finish of the innerface of a thin flexible film air-sealed to the outer surface of the facing before curing.

Abstract: Neurologic dysfunction resulting from stroke is diminished by administering to a patient an effective amount of a tetra-substituted pyrazine over a relatively continuous regimen. Conveniently, an initial bolus is administered to bring the level of the drug up to a pre-determined blood level, followed by continuous infusion employing a pump or by continuous intravenous infusion.

Abstract: The invention relates to synthetic coatings applied to substrates to simulate natural stone. The synthetic coatings are curable and saturated with a thin coating of fine particulate material. An implement is then used to tamp the coated surface to produce a natural stone appearance.

Abstract: An artificial decorative rock of foamed synthetic plastic having a body with an outer surface resembling the concavities and convexities of a natural rock has its outer surface coated with a strengthening layer of epoxy resin filled with hard sand-like particles which give the outer surface a rock simulating, grained texture. By forming a hollow within the surface of one body to complimentarily accommodate the outer surface of another body, one or more artificial decorative rocks can be nested, one within the other. By further shaping the uppermost outer surface of such hollow body to provide a stable support base, the body with the hollow extending upwardly can serve as a container.