Abstract: The disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprising compounds of formula (I), as well as methods of their use and preparation, are also described.

Abstract: The invention provides compounds of formula I: and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

Abstract: The invention provides compounds of formula I: and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

Abstract: The invention provides compounds of formula (I) and salts thereof wherein R4-R8 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

Abstract: The invention provides compounds of formula (I): and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

Abstract: The invention provides compounds of formula (I) and salts thereof wherein R4-R8 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

Abstract: The invention provides compounds of formula (I): and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.

Abstract: The present invention provides a cut stone including a top surface and a bottom surface and a girdle. The top surface includes a first facet row having 18 facets, a second facet row having 6 facets, and a third facet row having 6 facets. The bottom surface includes a first facet row having 18 facets, a second facet row having 6 facets, and a third facet row having 6 facets. The girdle is disposed between the first facet row of the top surface and the first facet row of the bottom surface.

Abstract: A memory exhaustion condition is handled in a data processing system having first and second regions of physical memory. The memory exhaustion condition is detected while the second region is mirroring at least part of the first region. In response to the memory exhaustion condition, memory mirroring is at least partially deactivated and at least part of the second region is utilized to augment the first region, such that the memory exhaustion condition is eliminated. In an illustrative embodiment, the data processing system compresses real memory into the first region of physical memory, and the memory exhaustion condition arises when the first region lacks sufficient available capacity to accommodate current requirements for real memory. The memory exhaustion condition is eliminated by compressing at least part of the real memory into the second region.