Abstract: Methods and systems for managing content items are described. A content item may be separated into components, such as chroma components, luminance components, and audio components. For more efficient management of the content, including for storage and delivery of the content, the separate components may be stored at different locations. For example, chroma components may be stored on a central server, while luminance and audio components are stored at other locations, such as edge servers, or vice versa, to accommodate network efficiency considerations. When content is delivered to a player, two or more separate streams carrying different content components may be delivered to the player.

Abstract: Systems and methods of online marketing, monitoring and control for merchants are disclosed. Third party providers are crawled to obtain information about a plurality of merchants and correlate the merchant information to create a merchant database. Third party providers are monitored for merchant information, and information about the merchants is stored. Alerts are provided to subscribing merchants when an alert trigger is identified within the system or at a third party provider. The method allows the subscribing merchant to view and respond to reviews, view and maintain online listings, prepare and send consumer offers, and prepare and send communications to consumers, all directly from the system. The method allows the subscribing merchant to view information and analyses for competing merchants. An overall marketing score for merchants is prepared and displayed. The method may be performed on a server and accessed via an Internet browser and mobile device applications.

Abstract: Systems and methods of online marketing, monitoring and control for merchants are disclosed. Third party providers are crawled to obtain information about a plurality of merchants and correlate the merchant information to create a merchant database. Third party providers are monitored for merchant information, and information about the merchants is stored. Alerts are provided to subscribing merchants when an alert trigger is identified within the system or at a third party provider. The method allows the subscribing merchant to view and respond to reviews, view and maintain online listings, prepare and send consumer offers, and prepare and send communications to consumers, all directly from the system. The method allows the subscribing merchant to view information and analysis for competing merchants. An overall marketing score for merchants is prepared and displayed. The method may be performed on a server and accessed via an Internet browser and mobile device applications.

Abstract: Systems and methods of online marketing, monitoring and control for merchants are disclosed. Third party providers are crawled to obtain information about a plurality of merchants and correlate the merchant information to create a merchant database. Third party providers are monitored for merchant information, and information about the merchants is stored. Alerts are provided to subscribing merchants when an alert trigger is identified within the system or at a third party provider. The method allows the subscribing merchant to view and respond to reviews, view and maintain online listings, prepare and send consumer offers, and prepare and send communications to consumers, all directly from the system. The method allows the subscribing merchant to view information and analyses for competing merchants. An overall marketing score for merchants is prepared and displayed. The method may be performed on a server and accessed via an Internet browser and mobile device applications.

Abstract: A personalized coupon system is disclosed. A localized offer list may be provided to a consumer including a plurality of offers from merchants in a location near the location of the consumer. The offers included in the offer list may be selected by the system based on progressive and regressive rules. When offers are redeemed, the system receives notification of offer redemption. The offer list and personalized electronic communications to the consumer may include offers based on prior activities of the consumer which are tracked by the system. The offer list and personalized electronic communications may include offers based on the activities of other consumers having similar geography and/or demographic information to the consumer. The activities may include viewing, selecting, obtaining, printing and redeeming offers from merchants. Behavior tracking information, maps and graphics may be provided to merchants so that they may understand the success of offers.

Abstract: A series of 2-(Purin-9-yl)-tetrahydrofuran-3,4-diol derivatives with broad anti-inflammatory properties which inhibit leukocyte recruitment and activation and which are agonists of the adenosine 2a receptor are described.

Abstract: This invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts and hydrates thereof, in which R.sub.1 represents a hydrogen atom or an alkyl, alkanoyl, aroyl or trifluoroalkyl group;R.sub.2 represents a hydrogen atom or an alkyl or alkenyl group or C.sub.2-6 alkyl group substituted by a hydroxy or alkoxy group;X represents a sulphur atom or NH;Y represents an oxygen or sulphur atom or a bond;m represents 1, 2 or 3; andn represents 2, 3 or 4.The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.