Patents by Inventor David Bechard

David Bechard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-15 AND IL-15RAPLHA SUSHI DOMAIN BASED MODULOKINES
    Publication number: 20160175459
    Abstract: The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an immunomodulatory antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R? or derivatives thereof; and uses thereof.
    Type: Application
    Filed: August 8, 2014
    Publication date: June 23, 2016
    Inventors: Alain GEY, Eric TARTOUR, David BECHARD
  • CYTOKINE DERIVED TREATMENT WITH REDUCED VASCULAR LEAK SYNDROME
    Publication number: 20160068584
    Abstract: The present invention relates to a pharmaceutical composition for treating a cancer or an infection in a subject by administrating an amount of an IL-15 derivative conjugate so as to induce a proliferation of natural killer cells (NK cells) which is the same or higher than the one obtained with high dose of interleukin-2 (HDIL-2); eventually associated with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 22, 2014
    Publication date: March 10, 2016
    Inventors: David Bechard, Nathalie Chaput, Melanie Desbois
  • AN IL-15 AND IL-15R\alpha SUSHI DOMAIN BASED IMMUNOCYTOKINES
    Publication number: 20150152188
    Abstract: The immunocytokine includes (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to the conjugate, wherein the conjugate includes (i) a polypeptide including the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide including the amino acid sequence.
    Type: Application
    Filed: June 22, 2012
    Publication date: June 4, 2015
    Inventors: Sebastien Daniel Morisseau, Géraldine Teppaz, Yannick Laurent Joseph Jacques, Bruno Gilbert Marc Robert, Guy Luc Michel De Martynoff, David Bechard
  • Kit and method for detecting the ESM-1 protein
    Patent number: 7473564
    Abstract: The invention concerns a kit for the detection of protein ESM-1 in a sample, comprising: a) a first antibody specifically binding to the N-terminal region of protein ESM-1 contained between the amino acid in position 20 and the amino acid in position 78 of the amino acid sequence of this protein; and b) a second antibody specifically binding to the C-terminal region contained between the amino acid in position 79 and the amino acid in position 184 of the amino acid sequence of protein ESM-1.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: January 6, 2009
    Assignees: Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale
    Inventors: Philipp Lassalle, David Bechard, André-Bernard Tonnel
  • Use of a compound antagonist of ESM-1 protein for producing a medicine for treating cancer
    Patent number: 7306797
    Abstract: Use of an antagonist compound of protein ESM-1 for the production of a drug for the treatment of a cancer.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: December 11, 2007
    Assignees: Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Philippe Lassalle, David Bechard, André-Bernard Tonnel
  • Use of a compound antagonist of esm-1 protein for producing a medicine for treating cancer
    Publication number: 20040234526
    Abstract: Use of an antagonist compound of protein ESM-1 for the production of a drug for the treatment of a cancer.
    Type: Application
    Filed: April 26, 2004
    Publication date: November 25, 2004
    Inventors: Philippe Lassalle, David Bechard, Andre-Bernard Tonnel
  • Kit and method for detecting the esm-1 protein
    Publication number: 20040063164
    Abstract: The invention concerns a kit for the detection of protein ESM-1 in a sample, comprising:
    Type: Application
    Filed: October 21, 2003
    Publication date: April 1, 2004
    Inventors: Philippe Lassalle, David Bechard, Andre-Bernard Tonnel