Abstract: A sheet material handling equipment includes a handling fixture having a frame adapted for attachment to a robot or manipulator; at least two arms anchored to the frame, each arm being formed by at least two semi-arms pivotally connected to each other and including a gripping member at its free end, the pivotal connection including a rotatable joint with a joint coupling having a joint brake, which are passive with a pressure or electric lock; and a first control line for distributing electrical power, and/or air, and/or hydraulic fluid for controlling the joint and/or the gripping member connected via an adapter to (a) an electrical power supply, and/or hydraulic fluid, and/or air to the robot or manipulator and to (b) a work line control unit, and an adjusting fixture structured to actively adjust a position of at least one of the arms and/or to unlock the joint brake.

Abstract: The invention relates to a thermostable FGF10 polypeptide possessing FGF10 activity and having or comprising at least 85% sequence identity to SEQ ID NO:3 that has or comprises an amino acid sequence from Ser69 to Ser208 of SEQ ID NO:1, or to SEQ ID NO:5 that has or comprises an amino acid sequence from Leu40 to Ser208 of SEQ ID NO:1, or the fragments thereof, comprising at least an amino acid substitution L152F. Preferably, any of amino acid substitutions V123I, Q175E, and N181D can be further included. The invention further discloses the use of subjected thermostable FGF10 polypeptides in regenerative medicine or other related medical applications or cosmetics. Further, it discloses a culture medium comprising subjected thermostable FGF10 polypeptides suitable for proliferation and differentiation of the human embryonic stem cells or formation and differentiation of spheroids and organoids.

Abstract: The present invention includes polynucleotides that encode novel coelenterazine-utilizing luciferases as well as fragments and mutants thereof having at least 85% sequence identity. The sequences were generated by ancestral sequence reconstruction combined with single-point mutations and transplantation of important regions from the related Renilla reniformis luciferase protein. The luciferases according to the present invention exhibit modulated properties including at least one of: increased bioluminescence emission stability and half-life; increased affinity towards substrate over the product (suppressed product inhibition); increased thermostability; increased glow-type effectivity; and modulated emission maximum.

Abstract: The invention provides an isolated thermostable polypeptide possessing FGF2 activity and having at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof, and comprising at least one amino acid substitution R31L and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. Further it discloses a culture medium comprising subjected FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.

Abstract: The invention provides an isolated thermostable polypeptide possessing FGF2 activity and having at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof, and comprising at least one amino acid substitution R31L and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. Further it discloses a culture medium comprising subjected FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.

Abstract: Methods and devices provide a tactile output surface that can communicate information to users via their sense of touch. The tactile output surface may include a plurality of tactile elements which may be activated to represent various information in a manner that can be understood by touching the device. A mobile device may present tactile output surfaces on one or multiple surfaces, and the user may touch the device after of tactile feedback functionality to obtain information from the one or more tactile output surfaces. In an embodiment, a mobile device may be configured to obtain information from an information source and present the information on a tactile output surface so that the user can perceive the information without having to look at the device. A variety of technologies may be used to create actuatable tactile elements.

Abstract: Methods and systems are provided for detecting a grip event on a touchscreen display and adjusting the displayed content based on the location of the grip event. The content that is covered by a grip event is identified and moved out from under the grip event by adjusting the displayed content layout. The area of the grip event may be determined to allow for adjusting the layout of the displayed. Alerts may be implemented to alert a user when there is a change in a content that is covered by a grip event. The grip event outline may be estimated and menu icons or icons may be positioned and displayed in close contour profile to estimated outline of the grip event. A grip event location may be suggested based on a user's touch habits or display content layout.

Abstract: Methods and devices provide a gesture activated file sharing functionality enabling users to share files with other nearby computing devices. The file sharing functionality may include establishing wireless links with nearby devices and determine their relative locations. The computing device may detect a file sharing motion of the computing device from accelerometers and transmit files to or request files from a nearby device in response. Base on motion parameters, e.g., direction, speed and/or shape, the computing device may identify a targeted device to which a file may be transmitted or from which a file may be requested. The computing device may request user verification of the identified device and send a request to transmit files to the targeted device. The computing devices may transmit files using networks and addresses provided over the device-to-device communication links.

Abstract: Methods and devices provide a tactile output surface that can communicate information to users via their sense of touch. The tactile output surface may include a plurality of tactile elements which may be activated to represent various information in a manner that can be understood by touching the device. A mobile device may present tactile output surfaces on one or multiple surfaces, and the user may touch the device after of tactile feedback functionality to obtain information from the one or more tactile output surfaces. In an embodiment, a mobile device may be configured to obtain information from an information source and present the information on a tactile output surface so that the user can perceive the information without having to look at the device. A variety of technologies may be used to create actuatable tactile elements.

Abstract: Methods and devices provide a gesture activated file sharing functionality enabling users to share files with other nearby computing devices. The file sharing functionality may include establishing wireless links with nearby devices and determine their relative locations. The computing device may detect a file sharing gesture and transmit files to or request files from a nearby device in response to the gesture. Base on gesture parameters, e.g., direction, speed and shape, and computing device attitude parameters, e.g., tilt angle and pointing direction, the computing device may identify a targeted device to which a file may be transmitted. The computing device may request user verification of the identified device and send a request to transmit files to the targeted device. The computing devices may transmit files using networks and addresses provided over the device-to-device communication links.

Abstract: Methods and systems are provided for detecting a grip event on a touchscreen display and adjusting the displayed content based on the location of the grip event. The content that is covered by a grip event is identified and moved out from under the grip event by adjusting the displayed content layout. The area of the grip event may be determined to allow for adjusting the layout of the displayed. Alerts may be implemented to alert a user when there is a change in a content that is covered by a grip event. The grip event outline may be estimated and menu icons or icons may be positioned and displayed in close contour profile to estimated outline of the grip event. A grip event location may be suggested based on a user's touch habits or display content layout.

Abstract: Methods and devices provide a gesture activated file sharing functionality enabling users to share files with other nearby computing devices. The file sharing functionality may include establishing wireless links with nearby devices and determine their relative locations. The computing device may detect a file sharing motion of the computing device from accelerometers and transmit files to or request files from a nearby device in response. Base on motion parameters, e.g., direction, speed and/or shape, the computing device may identify a targeted device to which a file may be transmitted or from which a file may be requested. The computing device may request user verification of the identified device and send a request to transmit files to the targeted device. The computing devices may transmit files using networks and addresses provided over the device-to-device communication links.

Abstract: Methods and devices provide a gesture activated file sharing functionality enabling users to share files with other nearby computing devices. The file sharing functionality may include establishing wireless links with nearby devices and determine their relative locations. The computing device may detect a file sharing gesture and transmit files to or request files from a nearby device in response to the gesture. Base on gesture parameters, e.g., direction, speed and shape, and computing device attitude parameters, e.g., tilt angle and pointing direction, the computing device may identify a targeted device to which a file may be transmitted. The computing device may request user verification of the identified device and send a request to transmit files to the targeted device. The computing devices may transmit files using networks and addresses provided over the device-to-device communication links.