Abstract: Designed polypeptides that bind specifically to a defined protein target are provided, as well as methods for their design and use.

Abstract: Implementations described and claimed herein provide systems and methods for object customization.

Abstract: An aerosol delivery device including a power supply; a vaporizer arranged to selectively receive power from the power supply to generate an aerosol from an aerosol precursor material for user inhalation; and a first electrical interface arranged to provide an electrical connection between the aerosol delivery device and a second aerosol delivery device so as to at least one of: supply power to or receive power from the second aerosol delivery device, or supply control signals to or receive control signals from the second aerosol delivery device.

Abstract: An example system may include an energy storage unit and various processors configured to communicate with components of the energy storage unit. The example system may determine a consumption model that predicts a future consumption for a node based on local power consumption for the node. The system may receive weather forecast data for the node and determine a power production model for the node that predicts a future power production using the weather forecast data. The system may compute a predicted power differential using the consumption model, the production model, and a current context of the node. The system may perform automated operations using the predicted power differential, such as charging or discharging an energy storage unit or controlling one or more power loads.

Abstract: Systems and methods of the present disclosure relate to identifying geometric features of a conduit. A method includes controlling a flow into or out of a conduit to induce pressure waves in the conduit; measuring, with a pressure transducer, pressure responses in the conduit due to contact of the pressure waves with a geometric feature of the conduit; and identifying the geometric feature, based on the pressure responses.

Abstract: A hook anchor for anchoring a fixation rod to a bone is disclosed. The hook anchor includes a hook body shaped in a curve of diminishing radius and a locking mechanism. The locking mechanism is to securely fix the hook anchor to the fixation rod. The curve of diminishing radius may be the shape of at least a portion of a Fibonacci curve. The bone can include at least one of a rib, a pelvis, and a vertebra. The hook body can be configured to engage with at least one of a spinous process a transverse process, and a pedicle of the vertebra.

Abstract: A device is disclosed. The device contains a first light source configured to excite fluorescence emission of a first contaminant on a surface, and a first optical sensor configured to capture one or more images of the fluorescence emission of the first contaminant.

Abstract: A gearbox may include a drive spindle and several interconnected gear clusters arranged in a housing. A first of the gear clusters is coaxially fastened to the spindle, and has an outboard gear and an inboard gear. The first gear cluster drives a belt to operate one or more of the other gear clusters, and the inboard gear is physically divided into a plurality of segments. A shifting system for the gearbox includes an actuator configured to urge the segments of the inboard gear of the first gear cluster into and out of the plane of the belt, such that a gear ratio of the gearbox is changeable without displacing the belt out of the plane.

Abstract: In some implementations, a system can be configured to allow remote control devices to quietly obtain status information related to various audio/video playback devices. For example, a streaming device (e.g., a user device, phone, etc.) can establish a streaming connection to a playback device. The playback device can be configured to only accept a single streaming connection (i.e., master connection). A remote control device (e.g., a user device, phone, etc.) can quietly connect (i.e., control connection) to the playback device without interrupting the master connection to obtain status information related to the playback device and or the media being streamed to the playback device. The remote control device can provide commands through the control connection to adjust the playback of the streamed media at the playback device.

Abstract: A method for determining analytics for service experience for a Network Slice instance in a network comprising one or more network entities is provided. The method includes obtaining first information for determining a mapping between a set of one or more user equipment (UEs) and a set of one or more Network Slice instances, obtaining second information for determining the analytics of the set of one or more UEs, and determining the analytics for a Network Slice instance based on the first information and the second information.

Abstract: A system can be used for generating a pressure signal in a flow path defined by a tubular. The system can include a pressure source, a valve, and a controller. The controller can output a command to control the pressure source for outputting a fluid hammer, according to the command, through the valve and into a flow path defined by a wellbore tubular. The system can be positioned external to the flow path. The system can determine, based on the reflection signal, a presence of a deposition, a blockage, or a leak within the flowline while the flowline is in operation.

Abstract: A gearbox may include a drive spindle and several interconnected gear clusters arranged in a housing. A first of the gear clusters is coaxially fastened to the spindle, and has an outboard gear and an inboard gear. The first gear cluster drives a belt or chain to operate one or more of the other gear clusters, and the inboard gear is physically divided into a plurality of segments. A shifting system for the gearbox includes an actuator configured to urge the segments of the inboard gear of the first gear cluster into and out of the plane of the belt or chain via a toggle and slider mechanism, such that a gear ratio of the gearbox is changeable without displacing the belt or chain out of the plane.

Abstract: A connector assembly of a cartridge of an electronic vaping device may be formed by metal in-molding. The connector assembly may include a connector body that is integrally formed. The connector body may include a base portion that is generally cylindrical, a nose portion extending from a first end of the base portion, and at least two slots extending longitudinally through the base portion and on opposing sides of the nose portion. An electrical lead extends through each of the at least two slots.

Abstract: A pigging tool may include a housing positionable in a pipeline. The housing may define a bypass channel that extends along an axis that is nonparallel to a longitudinal axis of the housing. An energy generation device can be positioned in the bypass channel of the housing such that fluid is receivable by the energy generation device to generate energy for the pigging tool. Further, an energy storage device may store energy generated from the energy generation device. The energy storage device may provide the pigging tool with energy to perform one or more operations in the pipeline.

Abstract: Disclosed herein is a golf club head comprising at least one crown opening and at least one crown insert attached to the body and covering the at least one crown opening. The golf club head further comprises at least one sole opening and at least one sole insert attached to the body and covering the at least one sole opening. The golf club head additionally includes at least one weight member configured to clamp first and second ledges at selected locations along a sliding weight track. The golf club head also comprise a coefficient of restitution (COR) feature located on the sole of the golf club head. The at least one crown insert is formed from a composite material having a density between 1 g/cc and 2 g/cc. The at least one sole insert is formed from a composite material having a density between 1 g/cc and 2 g/cc.

Abstract: Disclosed golf club heads include a body defining an interior cavity, a striking surface, a sole, a crown, and a hosel, which is configured to provide improved aerodynamic and inertia generating properties of the golf club head. Certain embodiments include an inertia generator positioned in the sole between an area proximate the club head's center of gravity and a position toeward of the center of gravity at the rear of the golf club head. Some embodiments include fixed or removable mass elements, weights or weight assemblies positioned in the sole, including, in some instances, within or adjacent to the inertia generator. In particular embodiments, one or more weight assemblies are movably retained within a weight channel defining a path along the sole.

Abstract: A pigging tool may include a housing positionable in a pipeline. The housing may define a bypass channel that extends along an axis that is nonparallel to a longitudinal axis of the housing. An energy generation device can be positioned in the bypass channel of the housing such that fluid is receivable by the energy generation device to generate energy for the pigging tool. Further, an energy storage device may store energy generated from the energy generation device. The energy storage device may provide the pigging tool with energy to perform one or more operations in the pipeline.

Abstract: A hook anchor for anchoring a fixation rod to a bone is disclosed. The hook anchor includes a hook body shaped in a curve of diminishing radius and a locking mechanism. The locking mechanism is to securely fix the hook anchor to the fixation rod. The curve of diminishing radius may be the shape of at least a portion of a Fibonacci curve. The bone can include at least one of a rib, a pelvis, and a vertebra. The hook body can be configured to engage with at least one of a spinous process a transverse process, and a pedicle of the vertebra.

Abstract: Disclosed herein is a golf club head comprising at least one crown opening and at least one crown insert attached to the body and covering the at least one crown opening. The golf club head further comprises at least one sole opening and at least one sole insert attached to the body and covering the at least one sole opening. The golf club head additionally includes at least one weight member configured to clamp first and second ledges at selected locations along a sliding weight track. The golf club head also comprise a coefficient of restitution (COR) feature located on the sole of the golf club head. The at least one crown insert is formed from a composite material having a density between 1 g/cc and 2 g/cc. The at least one sole insert is formed from a composite material having a density between 1 g/cc and 2 g/cc.

Abstract: A connector assembly of a cartridge of an electronic vaping device may be formed by metal in-molding. The connector assembly may include a connector body that is integrally formed. The connector body may include a base portion that is generally cylindrical, a nose portion extending from a first end of the base portion, and at least two slots extending longitudinally through the base portion and on opposing sides of the nose portion. An electrical lead extends through each of the at least two slots.