Patents by Inventor David Bernasconi

David Bernasconi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cross-talk correction in multiplexing analysis of biological sample
    Patent number: 10527549
    Abstract: A method for determining fluorescence values {?ispe}i?{1, 2, . . . , I} of a set of I fluorescent microparticles {?Pi}i?{1, 2, . . . , I} of a multiplexed analysis, the microparticles being in a monolayer arrangement, includes acquiring a digital fluorescence image of the set of fluorescent microparticles {?Pi}i?{1, 2, . . . , I}; and computing, for each fluorescent microparticle ?Pi in the set of fluorescent microparticles {?Pi}i?{1, 2, . . . , I}, a fluorescence value ?imeas based only on pixels of the acquired image corresponding to said fluorescent microparticle ?Pi. The method includes computing the fluorescence value ?ispe of the fluorescent microparticle ?Pi by correcting its first fluorescence ?imeas by a cross-talk fluorescence contribution ?icross in the first fluorescence ?imeas from other fluorescent microparticles {?Pj}j?i in the set of fluorescent microparticles {?Pi}i?{1, 2, . . . , I}.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: January 7, 2020
    Assignee: MYCARTIS N.V.
    Inventors: David Rebetez, David Bernasconi, Mathieu Gaillard, Didier Falconnet, José Gil
  • CROSS-TALK CORRECTION IN MULTIPLEXING ANALYSIS OF BIOLOGICAL SAMPLE
    Publication number: 20180275059
    Abstract: A method for determining fluorescence values {?ispe}i?{1, 2, . . . , I} of a set of I fluorescent microparticles {?Pi}i?{1, 2, . . . , I} of a multiplexed analysis, the microparticles being in a monolayer arrangement, includes acquiring a digital fluorescence image of the set of fluorescent microparticles {?Pi}i?{1, 2, . . . , I}; and computing, for each fluorescent microparticle ?Pi in the set of fluorescent microparticles {?Pi}i?{1, 2, . . . , I}, a fluorescence value ?imeas based only on pixels of the acquired image corresponding to said fluorescent microparticle ?Pi. The method includes computing the fluorescence value ?ispe of the fluorescent microparticle ?Pi by correcting its first fluorescence ?imeas by a cross-talk fluorescence contribution ?icross in the first fluorescence ?imeas from other fluorescent microparticles {?Pj}j?i in the set of fluorescent microparticles {?Pi}i?{1, 2, . . . , I}.
    Type: Application
    Filed: September 21, 2016
    Publication date: September 27, 2018
    Inventors: David Rebetez, David Bernasconi, Mathieu Gaillard, Didier Falconnet, José Gil