Patents by Inventor David Bickar

David Bickar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6338967
    Abstract: Reagent composition and quantities used to prepare a simple, solid stable and reproducible protein assay and reproducible solventless protein assay standard. The method of preparing the protein assay and protein assay standards is also described. A solidifying agent such as a solid acid is added to the dye reagent solution prior to removal of solvent so as to produce a solid dye assay reagent.
    Type: Grant
    Filed: July 10, 1999
    Date of Patent: January 15, 2002
    Inventor: David Bickar
  • Patent number: 6241946
    Abstract: A method for preparing a solventless protein standard is disclosed in which a solventless dye indicator and a predetermined amount of solventless protein are placed in an appropriate receptacle such as the well of a multiwell plate. This results in a solventless protein standard in which the solventless protein and the solventless dye are contained within the same receptacle. When an appropriate solvent is added to the receptacle, the protein and dye react together to produce a color change which is detectable, and which can be used as a standard for a protein assay using that dye. Also claimed is the solventless protein assay standard produced by the process.
    Type: Grant
    Filed: February 10, 1998
    Date of Patent: June 5, 2001
    Inventor: David Bickar
  • Patent number: 5496737
    Abstract: A method for preparing a solventless protein standard is disclosed in which a solventless dye indicator and a predetermined amount of solventless protein are placed in an appropriate receptacle such as the well of a multiwell plate. This results in a solventless protein standard in which the solventless protein and the solventless dye are contained within the same receptacle. When an appropriate solvent is added to the receptacle, the protein and dye react together to produce a color change which is detectable, and which can be used as a standard for a protein assay using that dye. Also claimed is the solventless protein assay standard produced by the process.
    Type: Grant
    Filed: October 15, 1993
    Date of Patent: March 5, 1996
    Inventor: David Bickar
  • Patent number: 5082642
    Abstract: This invention relates to a method for catalyzing the reactionsQZ+H.sub.2 X?QZX (1)andQZX?QZ+H.sub.2 X (2)whereinQ=C or N;Z=O or S;X=O, S, NH or NR;R=C.sub.1 to C.sub.8 alkyl which may be linear, branched or cyclized,which comprises:contacting at least one polydentate nitrogen-containing chelating agent complexed with a metal atom with the reactants of one of said reactions, wherein said contacting takes place in the presence of a means for oxidizing when reaction (1) is catalyzed and in the presence of a means for reducing when reaction (2) is catalyzed. A particular reaction is the conversion of NO to NO.sub.2 using water and supported porphines, hemes, phthalocyanines, ethioporphrins sirohemes, particularly heme and heme compounds or derivatives such as methemoglobin, myoglobin, or hemin.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: January 21, 1992
    Assignee: Duke University
    Inventors: David Bickar, Celia Bonaventura, Joseph Bonaventura
  • Patent number: 4751068
    Abstract: This invention relates to a method for catalyzing the reactionsQZ+H.sub.2 X.fwdarw.QZX (1) psandQZX.fwdarw.QZ+H.sub.2 X (2)wherein Q=C or N;Z=O or S;X=O, S, NH or NR;R=C.sub.1 to C.sub.8 alkyl which may be linear, branched or cyclized,which comprises:contacting at least one polydentate nitrogen-containing chelating agent complexed with a metal atom with the reactants of one of said reactions, wherein said contacting takes place in the presence of a means for oxidizing when reaction (1) is catalyzed and in the presence of a means for reducing when reaction (2) is catalyzed.
    Type: Grant
    Filed: September 10, 1984
    Date of Patent: June 14, 1988
    Assignee: Duke University
    Inventors: David Bickar, Celia Bonaventura, Joseph Bonaventura