Patents by Inventor David Blair Cody

David Blair Cody has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inhibiting conversion of choline to trimethylamine (TMA)
    Patent number: 11246844
    Abstract: A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: February 15, 2022
    Assignees: The Procter & Gamble Company, The Cleveland Clinic Foundation
    Inventors: Stanley Leon Hazen, Jose Carlos Garcia-Garcia, George Franklin Gerberick, John August Wos, Xiaodong Gu, Michael Reilly, Mark Robert Sivik, Jodie Michelle Reed, David Blair Cody
  • Methods for inhibiting conversion of carnitine to trimethylamine (TMA)
    Patent number: 10786479
    Abstract: The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I): Wherein the compound is administered in an amount effective to inhibit conversion of carnitine to TMA in the individual.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: September 29, 2020
    Assignees: The Procter & Gamble Company, The Cleveland Clinic Foundation
    Inventors: Stanley Leon Hazen, Jose Carlos Garcia-Garcia, George Franklin Gerberick, John August Wos, David Thomas Stanton, Thomas Alfred Inglin, Michael Reilly, Angela Jane Deutsch, Jodie Michele Reed, David Blair Cody
  • Methods for inhibiting conversion of choline to trimethylamine (TMA)
    Patent number: 10780072
    Abstract: The invention provides one or more methods of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I): wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline in the individual.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: September 22, 2020
    Assignees: The Procter & Gamble Company, The Cleveland Clinic Foundation
    Inventors: Stanley Leon Hazen, Jose Carlos Garcia-Garcia, George Franklin Gerberick, John August Wos, David Thomas Stanton, Thomas Alfred Inglin, Michael Reilly, Angela Jane Deutsch, Jodie Michele Reed, David Blair Cody
  • METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA)
    Publication number: 20180000754
    Abstract: A method of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO by providing a composition comprising a compound set forth in Formula (I):
    Type: Application
    Filed: May 31, 2017
    Publication date: January 4, 2018
    Inventors: Stanley Leon Hazen, Jose Carlos Garcia-Garcia, George Franklin GERBERICK, John August WOS, Xiaodong GU, Michael REILLY, Mark Robert SIVIK, Jodie Michelle REED, David Blair CODY
  • METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA)
    Publication number: 20170151250
    Abstract: The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I): Wherein the compound is administered in an amount effective to inhibit conversion of carnitine to TMA in the individual.
    Type: Application
    Filed: December 1, 2016
    Publication date: June 1, 2017
    Inventors: Stanley Leon HAZEN, Jose Carlos GARCIA-GARCIA, George Franklin GERBERICK, John August WOS, David Thomas STANTON, Thomas Alfred INGLIN, Michael REILLY, Angela Jane DEUTSCH, Jodie Michele REED, David Blair CODY
  • METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA)
    Publication number: 20170151208
    Abstract: The invention provides one or more methods of inhibiting the conversion of choline to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositions comprising a compound set forth in Formula (I): wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline in the individual.
    Type: Application
    Filed: December 1, 2016
    Publication date: June 1, 2017
    Inventors: Stanley Leon HAZEN, Jose Carlos GARCIA-GARCIA, George Franklin GERBERICK, John August WOS, David Thomas STANTON, Thomas Alfred INGLIN, Michael REILLY, Angela Jane DEUTSCH, Jodie Michele REED, David Blair CODY
  • Branched-Chain Fatty Acids And Biological Production Thereof
    Publication number: 20110151526
    Abstract: A method for producing anteiso fatty acid is provided. The method comprises culturing a cell comprising at least one exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes at least one of the following reactions: conversion of pyruvate to citramalate; conversion of citramalate to citraconate; conversion of citraconate to ?-methyl-D-malate; conversion of ?-methyl-D-malate to 2-oxobutanoate; or conversion of threonine to 2-oxobutanoate, under conditions allowing expression of the polynucleotide(s) and production of anteiso fatty acid. Optionally the cell further comprises at least one exogenous or overexpressed polynucleotide comprising a nucleic acid sequence encoding a polypeptide that catalyzes conversion of 2-oxobutanoate to 2-aceto-2-hydroxy-butyrate, conversion of 2-aceto-2-hydroxy-butyrate to 2,3-dihydroxy-3-methylvalerate, and/or conversion of 2,3-dihydroxy-3-methylvalerate to ?-keto-3-methylvalerate.
    Type: Application
    Filed: December 20, 2010
    Publication date: June 23, 2011
    Inventors: Charles Winston Saunders, Jun Xu, Phillip Richard Green, David Blair Cody, Zubin Saresh Khambatta