Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.

Abstract: Method, techniques, and apparatus of providing obscured feature detection. The disclosed embodiments provide an obscured feature detector to be placed on a surface to detect an obscured feature obscured by the surface, the obscured feature detector having a plurality of sensor plates arranged in an array. Measurements, via a sensing circuit, of capacitance readings sensed by the sensor plates in a plurality of regions are taken, each region corresponding to an area surrounding one or more of the at least three sensor plates. A comparison is made of the sensed capacitance readings in different regions using a controller coupled to the sensing circuit. The controller identifies an edge of the obscured feature and a centerline of the obscured feature, based on the comparison of the sensed capacitance readings. The controller activates an edge indicator to indicate proximity to the edge of the obscured feature and a centerline indicator to indicate the centerline of the obscured feature.

Abstract: Various methods and systems are provided for wirelessly charging a digital x-ray detector of an x-ray imaging system in at least two orientations. In one example, a method comprises: detecting a digital x-ray detector in a charging area of an x-ray system, the charging area including a first power source; pairing the digital x-ray detector to the x-ray system via a wireless connection with the x-ray system; and wirelessly charging the digital x-ray detector via the first power source.

Abstract: Various methods and systems are provided for wirelessly charging a digital x-ray detector of an x-ray imaging system in at least two orientations. In one example, a method comprises: detecting a digital x-ray detector in a charging area of an x-ray system, the charging area including a first power source; pairing the digital x-ray detector to the x-ray system via a wireless connection with the x-ray system; and wirelessly charging the digital x-ray detector via the first power source.

Abstract: Various methods and systems are provided for wirelessly charging a digital x-ray detector of an x-ray imaging system in at least two orientations. In one example, a method comprises: detecting a digital x-ray detector in a charging area of an x-ray system, the charging area including a first power source; pairing the digital x-ray detector to the x-ray system via a wireless connection with the x-ray system; and wirelessly charging the digital x-ray detector via the first power source.

Abstract: Various methods and systems are provided for wirelessly charging a digital x-ray detector of an x-ray imaging system in at least two orientations. In one example, a method comprises: detecting a digital x-ray detector in a charging area of an x-ray system, the charging area including a first power source; pairing the digital x-ray detector to the x-ray system via a wireless connection with the x-ray system; and wirelessly charging the digital x-ray detector via the first power source.

Abstract: Methods and systems are provided for controlling movement of a mobile imaging system. In one example, a mobile imaging system includes a mobile drive system, an imaging assembly coupled to the mobile drive system, and a driving interface configured to move the imaging assembly relative to the mobile drive system both axially and radially in response to user manipulation, and further configured to generate signals in response to the axial movement of the imaging assembly, the mobile drive system configured to move in response to the signals.

Abstract: Methods and systems are provided for controlling movement of a mobile imaging system. In one example, a mobile imaging system includes a mobile drive system, an imaging assembly coupled to the mobile drive system, and a driving interface configured to move the imaging assembly relative to the mobile drive system both axially and radially in response to user manipulation, and further configured to generate signals in response to the axial movement of the imaging assembly, the mobile drive system configured to move in response to the signals.

Abstract: Methods and systems are provided for an adaptive state-of-charge for a portable imaging system. In one embodiment, a method comprises controlling an x-ray source to generate an x-ray exposure, measuring a voltage of a power supply coupled to the x-ray source during the x-ray exposure, and adjusting an available capacity of the power supply based on the voltage. In this way, the full capacity of a power supply may be utilized while compensating for aging of the power supply.

Abstract: Methods and systems are provided for an adaptive state-of-charge for a portable imaging system. In one embodiment, a method comprises controlling an x-ray source to generate an x-ray exposure, measuring a voltage of a power supply coupled to the x-ray source during the x-ray exposure, and adjusting an available capacity of the power supply based on the voltage. In this way, the full capacity of a power supply may be utilized while compensating for aging of the power supply.

Abstract: In one embodiment, a method for coordinating operation of X-ray detectors in a wireless X-ray system includes detecting multiple wireless X-ray detectors within an operative range of an X-ray base station, the detected X-ray detectors each having one of multiple possible statuses, including an active status corresponding to a designation of the X-ray detector as a desired recipient of radiation during a current X-ray imaging sequence, an inactive status corresponding to a designation of the X-ray detector as not the desired recipient of radiation during a current X-ray imaging sequence, and an unenabled status corresponding to the X-ray detector not being configured to operate with the X-ray base station. The method also includes determining the current status of each detected X-ray detector and displaying on a user-viewable screen a visual indication of the status of each detected X-ray detector.

Abstract: In one embodiment, a method for coordinating operation of X-ray detectors in a wireless X-ray system includes detecting multiple wireless X-ray detectors within an operative range of an X-ray base station, the detected X-ray detectors each having one of multiple possible statuses, including an active status corresponding to a designation of the X-ray detector as a desired recipient of radiation during a current X-ray imaging sequence, an inactive status corresponding to a designation of the X-ray detector as not the desired recipient of radiation during a current X-ray imaging sequence, and an unenabled status corresponding to the X-ray detector not being configured to operate with the X-ray base station. The method also includes determining the current status of each detected X-ray detector and displaying on a user-viewable screen a visual indication of the status of each detected X-ray detector.

Abstract: Certain embodiments of the present invention provide for a system for communication between a controller and a power supply using a communication interface. In an embodiment, a communication system includes a power supply having one or more diagnostics. The communication system also includes a controller, configured for controlling the power supply and monitoring the one or more diagnostics of the power supply. In addition, the communication system includes a communication interface, configured to receive from the controller and send from the power supply one or more signals. The communication system also includes a load, configured to operate using the power provided by said power supply.

Abstract: A surgical clip according to an embodiment includes a pair of jaws, pivoted together, with a spring holding the jaws together. Various design embodiments incorporate this structure and include additional features such as having jaws made of an MRI invisible material, and spring connected to the jaws with hinge joints. An applicator is also provided, particularly with a ball and socket connection to the surgical clip. A method of latching the applicator, and of handling the clip with the applicator are also provided.

Abstract: An energy transfer machine, for example, a positive displacement internal combustion device, has a fixed or rotating outer housing, an internal rotating carrier and one or more inner rotors with rotational axes which are offset from the inner rotor carrier rotational axis. Circumferentially expandable projections from the outer housing and rotor mesh with each other to define variable volume chambers.

Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.

Abstract: A digital radiographic imaging system includes an offset table for determining mechanical and structural offsets which would, if not corrected, misalign the source and detector during use. The method can correct for inaccuracies in mechanical linkages, examination rooms and other mounting structures, and “drift” induced during use of the system.

Abstract: An apparatus and method for lancing a surface provides an adjustable nozzle assembly that includes an interior nozzle, a collar, and an exterior nozzle with a surface that contacts the surface to be lanced. The exterior nozzle can then rotate relative to the interior nozzle and, thereby, vary the lancing depth of a lancet. The apparatus and method for lancing a surface also provides for a rearward body assembly that includes an interior tube, a lancet holder, an internal compression spring, a retainer, a rearward body, and an external compression spring. Longitudinal movement of the rearward body away from the interior tube can compress the interior compression spring and can, thereby, spring load the lancing device. The apparatus and method for assembling the adjustable nozzle assembly of the lancing device provides for an interior nozzle with an assembly groove and a ramped groove separated by a raised boss.

Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.