Patents by Inventor David Borcherding

David Borcherding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
    Patent number: 7429595
    Abstract: The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4 -diaminocyclohexyl)-purines of the formula where Z is selected from the group consisting of —S(O)2—, and —C(O)—.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: September 30, 2008
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: David Borcherding, Jennifer A. Dumont, Norton P. Peet, Paul S. Wright
  • Pyrazoles as inhibitors of tumor necrosis factor
    Publication number: 20060063796
    Abstract: The present invention provides compounds of Formula (I) and ester prodrugs, pharmaceutically acceptable salts or solvates of such compounds; or ester prodrugs of such salts or solvates; pharmaceutical compositions comprising such compounds, their preparation, and their pharmaceutical use in the treatment of disease states capable of being modulated by the inhibition of p38 kinase and/or tumor necrosis factor (TNF).
    Type: Application
    Filed: November 1, 2005
    Publication date: March 23, 2006
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: David Borcherding, Alexandre Gross, Patrick Shum, Nicole Willard, Brian Freed
  • Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
    Patent number: 6861524
    Abstract: The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines of the formula where Z is selected from the group consisting of —S(O)2—, and —C(O)—.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: March 1, 2005
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: David Borcherding, Jennifer A. Dumont, Norton P. Peet, Paul S. Wright
  • Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
    Publication number: 20040248908
    Abstract: The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines of the formula 1
    Type: Application
    Filed: October 2, 2003
    Publication date: December 9, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: David Borcherding, Jennifer A. Dumont, Norton P. Peet, Paul S. Wright
  • Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
    Publication number: 20030069259
    Abstract: The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and methods of using the same as antiproliferative agents or to prevent apoptosis.
    Type: Application
    Filed: October 31, 2001
    Publication date: April 10, 2003
    Inventors: David Borcherding, Jennifer A. Dumont, Norton P. Peet, Paul S. Wright