Patents by Inventor David Borhani

David Borhani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORGANOPHOSPHORUS NERVE AGENT HYDROLYZING ENZYMES
    Publication number: 20240141308
    Abstract: Aspects of the disclosure relate to phosphotriesterase (PTE) enzymes and PTE-related (PTER) enzymes and their use in hydrolyzing OPNAs.
    Type: Application
    Filed: April 15, 2022
    Publication date: May 2, 2024
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: David Borhani, Dylan Alexander Carlin, Alex Tucker
  • METHODS FOR SCREENING VOLTAGE-GATED PROTEINS
    Publication number: 20150087552
    Abstract: In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage-gated ion channel. In certain embodiments, the voltage-gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage-gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.
    Type: Application
    Filed: August 29, 2014
    Publication date: March 26, 2015
    Inventors: Morten Ostergaard JENSEN, David BORHANI, VISHWANATH Jogini
  • Indazole compounds
    Publication number: 20070282101
    Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
    Type: Application
    Filed: April 2, 2007
    Publication date: December 6, 2007
    Inventors: Anna Ericsson, Andrew Burchat, Kristine Frank, David Calderwood, Lily Abbott, Maria Argiriadi, David Borhani, Kevin Cusack, Richard Dixon, Thomas Gordon, Kelly Mullen, Robert Talanian, Xiaoyun Wu, Xiaolei Zhang, Lu Wang, Biqin Li, Claude Barberis, Neil Wishart
  • Method of identifying inhibitors of CDC25
    Publication number: 20020183249
    Abstract: The present invention relates to polypeptides which comprise the ligand binding domain of Cdc25, crystalline forms of these polypeptides and the use of these crystalline forms to determine the three dimensional structure of the catalytic domain of Cdc25. The invention also relates to the use of the three dimensional structure of the Cdc25 catalytic domain in methods of designing and/or identifying potential inhibitors of Cdc25 activity, for example, compounds which inhibit the binding of a native substrate to the Cdc25 catalytic domain.
    Type: Application
    Filed: March 1, 2001
    Publication date: December 5, 2002
    Inventors: Neil R. Taylor, David Borhani, David Epstein, Johannes Rudolph, Kurt Ritter, Taro Fujimori, Simon Robinson, Jens Eckstein, Andreas Haupt, Nigel Walker, Richard W. Dixon, Deborah Choquette, Jill Blanchard, Arthur Kluge, Kollol Pal, Nicholas Bockovich, Jon Come, Mark Hediger