Patents by Inventor David Bram Lewis

David Bram Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to induce and expand therapeutic alloantigen-specific human regulatory T cells in large-scale
    Patent number: 9480715
    Abstract: Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25? T cells by using CD40-activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4highCD25+Foxp3+ regulatory T cells.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: November 1, 2016
    Assignees: VERSITECH LIMITED, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Wenwei Tu, Yu-Lung Lau, David Bram Lewis
  • METHOD TO INDUCE AND EXPAND THERAPEUTIC ALLOANTIGEN-SPECIFIC HUMAN REGULATORY T CELLS IN LARGE-SCALE
    Publication number: 20140134145
    Abstract: Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25? T cells by using CD40-activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4highCD25+Foxp3+ regulatory T cells.
    Type: Application
    Filed: January 10, 2014
    Publication date: May 15, 2014
    Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, VERSITECH LIMITED
    Inventors: Wenwei Tu, Yu-Lung Lau, David Bram Lewis
  • Method to induce and expand therapeutic alloantigen-specific human regulatory T cells in large-scale
    Patent number: 8658159
    Abstract: Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25? T cells by using CD40-activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4highCD25+Foxp3+ regulatory T cells.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: February 25, 2014
    Assignees: Versitech Limited, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Wenwei Tu, Yu-Lung Lau, David Bram Lewis
  • METHOD TO INDUCE AND EXPAND THERAPEUTIC ALLOANTIGEN-SPECIFIC HUMAN REGULATORY T CELLS IN LARGE-SCALE
    Publication number: 20090324557
    Abstract: Methods for inducing, expanding, and/or generating alloantigen-specific regulatory T cells. Alloantigen-specific regulatory T cells can be induced, expanded, and/or generated from naive CD4+CD25?T cells by using CD40? activated B cells. The regulatory T cells can be human T cells. In one embodiment, the alloantigen-specific human regulatory T cells can be CD4hIghCD25+Foxp3+ regulatory T cells.
    Type: Application
    Filed: April 30, 2009
    Publication date: December 31, 2009
    Inventors: Wenwei Tu, Yu-Lung Lau, David Bram Lewis