Patents by Inventor David Brancazio
David Brancazio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12121353Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.Type: GrantFiled: June 8, 2023Date of Patent: October 22, 2024Assignee: YourBio Health, Inc.Inventor: David Brancazio
-
Publication number: 20240075448Abstract: Reactor systems, reactors, and removable liners for chemical and biological processes and manufacturing modules and systems using the same, are disclosed. Kits and methods of using the reactor systems and kits as with removable elements are also disclosed.Type: ApplicationFiled: September 5, 2022Publication date: March 7, 2024Applicant: ODH IP CORP.Inventors: Kersten Rapp, David Brancazio
-
Publication number: 20240066443Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.Type: ApplicationFiled: September 1, 2023Publication date: February 29, 2024Applicant: Massachusetts Institute of TechnologyInventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp, Naomi Elizabeth Barbara Briggs
-
Patent number: 11911719Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.Type: GrantFiled: July 20, 2020Date of Patent: February 27, 2024Assignee: Massachusetts Institute of TechnologyInventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp, Naomi Elizabeth Barbara Briggs
-
Patent number: 11786846Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.Type: GrantFiled: July 20, 2020Date of Patent: October 17, 2023Assignee: Massachusetts Institute of TechnologyInventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp, Naomi Elizabeth Barbara Briggs
-
Publication number: 20230309873Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.Type: ApplicationFiled: June 8, 2023Publication date: October 5, 2023Applicant: YourBio Health, Inc.Inventor: David Brancazio
-
Publication number: 20220133192Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.Type: ApplicationFiled: August 6, 2021Publication date: May 5, 2022Applicant: YourBio Health, Inc.Inventor: David Brancazio
-
Patent number: 11020352Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).Type: GrantFiled: May 26, 2020Date of Patent: June 1, 2021Assignee: Massachusetts Institute of TechnologyInventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
-
Publication number: 20210086112Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.Type: ApplicationFiled: July 20, 2020Publication date: March 25, 2021Applicant: Massachusetts Institute of TechnologyInventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp
-
Publication number: 20200352865Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).Type: ApplicationFiled: May 26, 2020Publication date: November 12, 2020Applicant: Massachusetts Institute of TechnologyInventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
-
Patent number: 10702481Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).Type: GrantFiled: February 15, 2018Date of Patent: July 7, 2020Assignee: Massachusetts Institute of TechnologyInventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
-
Publication number: 20180271791Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).Type: ApplicationFiled: February 15, 2018Publication date: September 27, 2018Applicant: Massachusetts Institute of TechnologyInventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
-
Publication number: 20170354609Abstract: The disclosure describes an injection molding process for coating a tablet core to produce a coated pharmaceutical tablet, wherein the injection-molded coating is substantially continuous (e.g., completely covers the tablet core with no openings), and describes the resulting coated pharmaceutical tablet. The disclosure describes compositions for coatings and tablet cores and equipment suitable for performing the process.Type: ApplicationFiled: June 12, 2017Publication date: December 14, 2017Applicant: Massachusetts Institute of TechnologyInventors: Vibha Puri, Parind Mahendrakumar Desai, Keith D. Jensen, David Brancazio, Eranda Harinath, Alexander Racine Martinez, Jung Hoon Chun, Richard Dean Braatz, Allan S. Myerson, Bernhardt Levy Trout
-
Publication number: 20170224264Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.Type: ApplicationFiled: October 19, 2016Publication date: August 10, 2017Applicant: Seventh Sense Biosystems, Inc.Inventor: David Brancazio
-
Patent number: 9228640Abstract: A transmission assembly comprises: a motor; a shift actuator mechanism coupled to the motor; a sun gear coupled to an output shaft of the motor; a first magnet assembly coupled to the sun gear; a ring gear assembly coupled to a shift coupler, the shift coupler being configured to engage via the shift actuator mechanism; a second magnet assembly coupled to a housing face plate, the housing face plate being coupled to an output gear box; and a planet carrier coupled to an output pinion in communication with the output gearbox. The planet carrier comprises at least one planet gear. In a first mode, the ring gear is locked to the first magnet assembly and configured to rotate with the sun gear, the ring gear being configured to prevent the rotation of the at least one planet gear about its own axis causing the planet carrier to rotate at the same speed as the sun gear.Type: GrantFiled: June 10, 2011Date of Patent: January 5, 2016Assignee: iRobot CorporationInventors: Timothy R. Ohm, Mark Robert Claffee, Martin Buehler, David Brancazio
-
Patent number: 8961902Abstract: A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.Type: GrantFiled: July 17, 2008Date of Patent: February 24, 2015Assignee: BioScale, Inc.Inventors: Peter W. Falb, David Brancazio, Eric France, Brett P. Masters, Michael F. Miller, Joshua R. Ormsby, Walker Sloan
-
Publication number: 20140336536Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.Type: ApplicationFiled: July 10, 2014Publication date: November 13, 2014Applicant: Seventh Sense Biosystems, Inc.Inventor: David Brancazio
-
Patent number: 8808202Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member.Type: GrantFiled: November 9, 2011Date of Patent: August 19, 2014Assignee: Seventh Sense Biosystems, Inc.Inventor: David Brancazio
-
Patent number: 8435463Abstract: An apparatus includes a housing having a support surface to support a cartridge, a socket attached to the housing, and an actuator associated with the socket. The socket surface includes one or more socket positioning members, a plurality of electrical contacts and a plurality of magnets. The socket is configured to move relative to the support surface of the housing, with the one or more socket positioning members located in a fixed relation to the plurality of electrical contacts so that when the socket is spaced proximate to the support surface of the housing, the one or more socket positioning members engage with the one or more cartridge positioning members to align the plurality of electrical contacts of the socket with the plurality of electrical contact pads of the cartridge. The actuator is configured to align each magnet with a respective fluid conduit of the processing device.Type: GrantFiled: June 18, 2012Date of Patent: May 7, 2013Assignee: BioScale, Inc.Inventors: Brett P Masters, Eric France, Peter Wight Falb, Matthew Kavalauskas, David Brancazio
-
Publication number: 20120263631Abstract: An apparatus includes a housing having a support surface to support a cartridge, a socket attached to the housing, and an actuator associated with the socket. The socket surface includes one or more socket positioning members, a plurality of electrical contacts and a plurality of magnets. The socket is configured to move relative to the support surface of the housing, with the one or more socket positioning members located in a fixed relation to the plurality of electrical contacts so that when the socket is spaced proximate to the support surface of the housing, the one or more socket positioning members engage with the one or more cartridge positioning members to align the plurality of electrical contacts of the socket with the plurality of electrical contact pads of the cartridge. The actuator is configured to align each magnet with a respective fluid conduit of the processing device.Type: ApplicationFiled: June 18, 2012Publication date: October 18, 2012Inventors: Brett Masters, Eric France, Peter Wight Falb, Matthew Kavalauskas, David Brancazio