Patents by Inventor David Brancazio

David Brancazio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12121353
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.
    Type: Grant
    Filed: June 8, 2023
    Date of Patent: October 22, 2024
    Assignee: YourBio Health, Inc.
    Inventor: David Brancazio
  • Publication number: 20240075448
    Abstract: Reactor systems, reactors, and removable liners for chemical and biological processes and manufacturing modules and systems using the same, are disclosed. Kits and methods of using the reactor systems and kits as with removable elements are also disclosed.
    Type: Application
    Filed: September 5, 2022
    Publication date: March 7, 2024
    Applicant: ODH IP CORP.
    Inventors: Kersten Rapp, David Brancazio
  • Publication number: 20240066443
    Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
    Type: Application
    Filed: September 1, 2023
    Publication date: February 29, 2024
    Applicant: Massachusetts Institute of Technology
    Inventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp, Naomi Elizabeth Barbara Briggs
  • Patent number: 11911719
    Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: February 27, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp, Naomi Elizabeth Barbara Briggs
  • Patent number: 11786846
    Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: October 17, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp, Naomi Elizabeth Barbara Briggs
  • Publication number: 20230309873
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.
    Type: Application
    Filed: June 8, 2023
    Publication date: October 5, 2023
    Applicant: YourBio Health, Inc.
    Inventor: David Brancazio
  • Publication number: 20220133192
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.
    Type: Application
    Filed: August 6, 2021
    Publication date: May 5, 2022
    Applicant: YourBio Health, Inc.
    Inventor: David Brancazio
  • Patent number: 11020352
    Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: June 1, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
  • Publication number: 20210086112
    Abstract: Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described.
    Type: Application
    Filed: July 20, 2020
    Publication date: March 25, 2021
    Applicant: Massachusetts Institute of Technology
    Inventors: David Brancazio, Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, Gerard Capellades Mendez, Clemence Neurohr, Kersten Rapp
  • Publication number: 20200352865
    Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
    Type: Application
    Filed: May 26, 2020
    Publication date: November 12, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
  • Patent number: 10702481
    Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: July 7, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
  • Publication number: 20180271791
    Abstract: Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
    Type: Application
    Filed: February 15, 2018
    Publication date: September 27, 2018
    Applicant: Massachusetts Institute of Technology
    Inventors: Allan S. Myerson, Mohammad A. Azad, Gregory J. Hammersmith, David Brancazio, Juan Guillermo Osorio Caicedo
  • Publication number: 20170354609
    Abstract: The disclosure describes an injection molding process for coating a tablet core to produce a coated pharmaceutical tablet, wherein the injection-molded coating is substantially continuous (e.g., completely covers the tablet core with no openings), and describes the resulting coated pharmaceutical tablet. The disclosure describes compositions for coatings and tablet cores and equipment suitable for performing the process.
    Type: Application
    Filed: June 12, 2017
    Publication date: December 14, 2017
    Applicant: Massachusetts Institute of Technology
    Inventors: Vibha Puri, Parind Mahendrakumar Desai, Keith D. Jensen, David Brancazio, Eranda Harinath, Alexander Racine Martinez, Jung Hoon Chun, Richard Dean Braatz, Allan S. Myerson, Bernhardt Levy Trout
  • Publication number: 20170224264
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.
    Type: Application
    Filed: October 19, 2016
    Publication date: August 10, 2017
    Applicant: Seventh Sense Biosystems, Inc.
    Inventor: David Brancazio
  • Patent number: 9228640
    Abstract: A transmission assembly comprises: a motor; a shift actuator mechanism coupled to the motor; a sun gear coupled to an output shaft of the motor; a first magnet assembly coupled to the sun gear; a ring gear assembly coupled to a shift coupler, the shift coupler being configured to engage via the shift actuator mechanism; a second magnet assembly coupled to a housing face plate, the housing face plate being coupled to an output gear box; and a planet carrier coupled to an output pinion in communication with the output gearbox. The planet carrier comprises at least one planet gear. In a first mode, the ring gear is locked to the first magnet assembly and configured to rotate with the sun gear, the ring gear being configured to prevent the rotation of the at least one planet gear about its own axis causing the planet carrier to rotate at the same speed as the sun gear.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: January 5, 2016
    Assignee: iRobot Corporation
    Inventors: Timothy R. Ohm, Mark Robert Claffee, Martin Buehler, David Brancazio
  • Patent number: 8961902
    Abstract: A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: February 24, 2015
    Assignee: BioScale, Inc.
    Inventors: Peter W. Falb, David Brancazio, Eric France, Brett P. Masters, Michael F. Miller, Joshua R. Ormsby, Walker Sloan
  • Publication number: 20140336536
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member.
    Type: Application
    Filed: July 10, 2014
    Publication date: November 13, 2014
    Applicant: Seventh Sense Biosystems, Inc.
    Inventor: David Brancazio
  • Patent number: 8808202
    Abstract: The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: August 19, 2014
    Assignee: Seventh Sense Biosystems, Inc.
    Inventor: David Brancazio
  • Patent number: 8435463
    Abstract: An apparatus includes a housing having a support surface to support a cartridge, a socket attached to the housing, and an actuator associated with the socket. The socket surface includes one or more socket positioning members, a plurality of electrical contacts and a plurality of magnets. The socket is configured to move relative to the support surface of the housing, with the one or more socket positioning members located in a fixed relation to the plurality of electrical contacts so that when the socket is spaced proximate to the support surface of the housing, the one or more socket positioning members engage with the one or more cartridge positioning members to align the plurality of electrical contacts of the socket with the plurality of electrical contact pads of the cartridge. The actuator is configured to align each magnet with a respective fluid conduit of the processing device.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: May 7, 2013
    Assignee: BioScale, Inc.
    Inventors: Brett P Masters, Eric France, Peter Wight Falb, Matthew Kavalauskas, David Brancazio
  • Publication number: 20120263631
    Abstract: An apparatus includes a housing having a support surface to support a cartridge, a socket attached to the housing, and an actuator associated with the socket. The socket surface includes one or more socket positioning members, a plurality of electrical contacts and a plurality of magnets. The socket is configured to move relative to the support surface of the housing, with the one or more socket positioning members located in a fixed relation to the plurality of electrical contacts so that when the socket is spaced proximate to the support surface of the housing, the one or more socket positioning members engage with the one or more cartridge positioning members to align the plurality of electrical contacts of the socket with the plurality of electrical contact pads of the cartridge. The actuator is configured to align each magnet with a respective fluid conduit of the processing device.
    Type: Application
    Filed: June 18, 2012
    Publication date: October 18, 2012
    Inventors: Brett Masters, Eric France, Peter Wight Falb, Matthew Kavalauskas, David Brancazio