Patents by Inventor David Brook

David Brook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONTRAST AGENTS FOR ENHANCED MAGNETIC RESONANCE IMAGING
    Publication number: 20260091145
    Abstract: The disclosure relates to compounds of the formula (Ia), (Ib), (IIa), and (IIb) and the use of the compounds of the formula (IIa) and (IIb) in method for imaging (e.g., magnetic resonance imaging) a subject in need thereof.
    Type: Application
    Filed: September 30, 2025
    Publication date: April 2, 2026
    Inventors: David Brook, David Paul Soulsby
  • Heterocyclyl substituted pyrrolopyridines that are inhibitors of the CDK12 kinase
    Patent number: 11407767
    Abstract: This invention related to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by the CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular, the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: August 9, 2022
    Inventors: David Brook, Chris Hayes, Nicholas Bennett, Matthew Palframan, Sue Cramp, Richard Bull, Michael Bodnarchuk
  • HETEROCYCLYL SUBSTITUTED PYRROLOPYRIDINES THAT ARE INHIBITORS OF THE CDK12 KINASE
    Publication number: 20200247824
    Abstract: This invention related to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by the CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular, the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein.
    Type: Application
    Filed: September 21, 2018
    Publication date: August 6, 2020
    Applicant: The University of Nottingham
    Inventors: David Brook, Chris Hayes, Nicholas Bennett, Matthew Palframan, Sue Cramp, Richard Bull, Michael Bodnarchuk
  • Car Sharing
    Publication number: 20120330696
    Abstract: Among other things, through an online site, owners of assets and borrowers of assets can arrange sharing transactions with respect to the assets. Online confirmation is provided to the owners and the borrowers that the arranged sharing transactions have been covered by insurance. Completion of the arranged sharing transactions is managed using information from electronic devices associated with the assets.
    Type: Application
    Filed: September 5, 2012
    Publication date: December 27, 2012
    Inventors: SHELBY CLARK, GUS HOLCOMB, DAVID BROOK, TARA REEVES, NABEEL AL-KADY, JONAH BLISS, ROBERT GUINN
  • CAR SHARING
    Publication number: 20110213629
    Abstract: Among other things, through an online site, owners of assets and borrowers of assets can arrange sharing transactions with respect to the assets. Online confirmation is provided to the owners and the borrowers that the arranged sharing transactions have been covered by insurance. Completion of the arranged sharing transactions is managed using information from electronic devices associated with the assets.
    Type: Application
    Filed: February 28, 2011
    Publication date: September 1, 2011
    Inventors: Shelby Clark, Gus Holcomb, David Brook, Tara Reeves, Nabeel Al-Kady, Jonah Bliss, Robert Guinn