Abstract: Rack-type backlight light emitting element (LEE) printed circuit boards (PCBs) with at least two layers to provide redundant current paths. This enables a PCB strip to be broken at designated perforations in the field in order to accommodate pipes or fixtures that require formation of a gap in the rack array. The entire length and width of an array can be sized in the field. A plurality of PCB arrays can be serially chained together with the system. A chain of PCB strips is snapped into clips, which in turn snap into rails that are fastened to a surface. The mounting system includes various types of clips, such as end clips, clips for different LEE patterns on the PCBs, and mounting clips to secure the rails to a surface.

Abstract: There is described herein a method for predicting response to anti-PD1 based therapy in a subject with cancer, the method comprising: providing a sample of peripheral blood from the subject; adding an IFN-I to the sample; assessing T-cell response to IFN-I stimulation in the peripheral blood sample by measuring the expression of IFN-I stimulated genes; and predicting a better outcome in response to anti-PD1 therapy if the assessment in the previous step indicates T-cell resistance to IFN-I stimulation and predicting a poorer outcome in response to anti-PD1 therapy if the assessment step indicates T-cell responsiveness to IFN-I stimulation.

Abstract: An excimer laser system includes first and second gas cylinders connected to a laser chamber for selectively supplying the laser chamber with gases that are needed to generate and emit laser pulsations having a certain energy level from the laser chamber. At least one of the first and second gas cylinders includes a halogen gas. The halogen gas is consumed during the operation of the excimer laser system. A computer system, included within the excimer laser system, is used to determine whether to resupply the laser chamber with halogen gas from the first and/or second cylinders, or to entirely flush out the gas contents of the laser chamber, and to resupply the flushed gas chamber with gas sourced from the first and/or second cylinders.

Abstract: A device for applying targeted phototherapy to an area of diseased skin to place a skin condition into remission and a method of determining a maximum tolerable dose of phototherapy applied to a treatment area of diseased skin to determine an optimum therapeutic dose to quickly place a skin condition into remission. The device can include a housing and an optical matrix arranged within the housing that are attached to a dosimetry device. The optical matrix includes a plurality of at least one of absorptive, reflective and/or partially transmissive regions or arrays of perforations that each permits a different percentage of light to be delivered to an individual's skin. Jigs can be included to arrange a plurality of varying exposures to be placed on the patient's skin. An assessment can then be made as to the maximum tolerable dose of phototherapy that can be applied to the individual's skin in order to place a skin condition into remission.

Abstract: The invention relates to the novel cotton variety designated 20B1091460. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 20B1091460. Also provided by the invention are methods of using cotton variety 20B1091460 and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 20B1091460 with itself or another cotton variety and plants and seeds produced by such methods.

Abstract: The invention relates to the novel cotton variety designated 20B1091458. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 20B1091458. Also provided by the invention are methods of using cotton variety 20B1091458 and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 20B1091458 with itself or another cotton variety and plants and seeds produced by such methods.

Abstract: Techniques herein provide an audience participation software application, system and method construction that enables remote and present users of the audience participation software application, system, and method to produce an accumulated output device effect wherein, components of the output device effect may be shared between the users, stored for further use, and/or used to control outputs of one or more communicatively coupled output device systems located and operated at one or more live entertainment events.

Abstract: Techniques herein provide an audience participation software application, system and method construction that enables remote and present users of the audience participation software application, system, and method to produce an accumulated output device effect wherein, components of the output device effect may be shared between the users, stored for further use, and/or used to control outputs of one or more communicatively coupled output device systems located and operated at one or more live entertainment events.

Abstract: In accordance with embodiments, there are provided mechanisms and methods for creating, exporting, viewing and testing, and importing custom applications in a multitenant database environment. These mechanisms and methods can enable embodiments to provide a vehicle for sharing applications across organizational boundaries. The ability to share applications across organizational boundaries can enable tenants in a multi-tenant database system, for example, to easily and efficiently import and export, and thus share, applications with other tenants in the multi-tenant environment.

Abstract: In accordance with embodiments, there are provided mechanisms and methods for creating, exporting, viewing and testing, and importing custom applications in a multitenant database environment. These mechanisms and methods can enable embodiments to provide a vehicle for sharing applications across organizational boundaries. The ability to share applications across organizational boundaries can enable tenants in a multi-tenant database system, for example, to easily and efficiently import and export, and thus share, applications with other tenants in the multi-tenant environment.

Abstract: The invention relates to inhibitors of CDK12 (cyclin-dependent kinase 12), and there use in the treatment or prevention of a disorder in a subject caused by the generation of repeat expansion transcripts.

Abstract: In accordance with embodiments, there are provided mechanisms and methods for creating, exporting, viewing and testing, and importing custom applications in a multitenant database environment. These mechanisms and methods can enable embodiments to provide a vehicle for sharing applications across organizational boundaries. The ability to share applications across organizational boundaries can enable tenants in a multi-tenant database system, for example, to easily and efficiently import and export, and thus share, applications with other tenants in the multi-tenant environment.

Abstract: Distributing communications to users within a network computing system may include monitoring, using a processor, communications between users exchanged within the network computing system, detecting, using the processor, a question within a first communication from a client device of a first user directed to a client device of a second user, and determining, using the processor, that the question is unanswered. Responsive to detecting an answer to the question in a second communication from a client device of a third user directed to the first user, a further communication notifying the second user of the answer to the question may be sent using a processor.

Abstract: Rack-type backlight light emitting element (LEE) printed circuit boards (PCBs) with at least two layers to provide redundant current paths. This enables a PCB strip to be broken at designated perforations in the field in order to accommodate pipes or fixtures that require formation of a gap in the rack array. The entire length and width of an array can be sized in the field. A plurality of PCB arrays can be serially chained together with the system. A chain of PCB strips is snapped into clips, which in turn snap into rails that are fastened to a surface. The mounting system includes various types of clips, such as end clips, clips for different LEE patterns on the PCBs, and mounting clips to secure the rails to a surface.

Abstract: This invention related to compounds that are inhibitors of the CDK12 kinase. The compounds are useful in the treatment of disorders mediated by the CDK12 kinase including myotonic dystrophy type 1 (DM1) and other disorders caused by the generation of RNA repeat expansion transcripts. In particular, the invention relates to compounds of the formula (I), or a pharmaceutically acceptable salts or N-oxides thereof, wherein R1a, R2, R3, R4a, R4b and R4c are as defined herein.

Abstract: In accordance with embodiments, there are provided mechanisms and methods for creating, exporting, viewing and testing, and importing custom applications in a multitenant database environment. These mechanisms and methods can enable embodiments to provide a vehicle for sharing applications across organizational boundaries. The ability to share applications across organizational boundaries can enable tenants in a multi-tenant database system, for example, to easily and efficiently import and export, and thus share, applications with other tenants in the multi-tenant environment.

Abstract: The invention relates to the novel cotton variety designated NG 2982 B3XF. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety NG 2982 B3XF. Also provided by the invention are methods of using cotton variety NG 2982 B3XF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety NG 2982 B3XF with itself or another cotton variety and plants and seeds produced by such methods.

Abstract: An excimer laser system includes first and second gas cylinders connected to a laser chamber for selectively supplying the laser chamber with gases that are needed to generate and emit laser pulsations having a certain energy level from the laser chamber. At least one of the first and second gas cylinders includes a halogen gas. The halogen gas is consumed during the operation of the excimer laser system. A computer system, included within the excimer laser system, is used to determine whether to resupply the laser chamber with halogen gas from the first and/or second cylinders, or to entirely flush out the gas contents of the laser chamber, and to resupply the flushed gas chamber with gas sourced from the first and/or second cylinders.

Abstract: A method, system and computer program product for performing a search from another individual's social perspective. A name or a portion of a name of an individual known by the user is received. A directory search is then performed pertaining to the individual known by the user. After the user identifies the known individual from the directory search results, a selection to perform a directory, content or document search from the known individual's social perspective is received. Such a search may be performed based on the social network of the known individual. In this manner, by performing such searches from the social perspective of the known individual, such as the individual who disclosed the name of the individual who the user would like to contact, the user will be more likely to identify the correct individual, content or document in a more efficient manner.

Abstract: The invention relates to the novel cotton variety designated NG 3930 B3XF. Provided h the invention are the seeds, plants, plant parts and derivatives of the cotton variety NG 3930 B3XF. Also provided by the invention are methods of using cotton variety NG 3930 B3XF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety NG 3930 B3XF with itself or another cotton variety, and plants and seeds produced by such methods.