Patents by Inventor David Brough

David Brough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors
    Patent number: 10570157
    Abstract: Inhibitor compounds are disclosed. The compounds are effective in the treatment of diseases or conditions in which interleukin 1 ? activity is implicated. Methods of synthesis of the compounds, as well as pharmaceutical compositions comprising the compounds are also disclosed.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: February 25, 2020
    Assignee: THE UNIVERSITY OF MANCHESTER
    Inventors: David Brough, Stuart McRae Allan, Sally Freeman, Alex George Baldwin
  • CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS
    Publication number: 20180215772
    Abstract: Inhibitor compounds are disclosed. The compounds are effective in the treatment of diseases or conditions in which interleukin 1 ? activity is implicated. Methods of synthesis of the compounds, as well as pharmaceutical compositions comprising the compounds are also disclosed.
    Type: Application
    Filed: July 28, 2016
    Publication date: August 2, 2018
    Inventors: David Brough, Stuart McRae Allan, Sally Freeman, Alex George Baldwin