Abstract: A method for monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. The method can optionally include optically detecting glucose concentration as a function of polarimetry and/or fluorescence. A system for monitoring glucose concentration can include devices described herein.

Abstract: Devices can be implanted in an eye to treat a dry eye condition. The devices include a body defining a lumen and having first and second ends and external and lumenal surfaces. The body has a length sufficient to provide fluid communication between the anterior chamber and tear film of the eye through the lumen when the device is implanted in the sclera. In some embodiments, the device is filterless. In some embodiments, a filter is included. The dry eye treatment devices provided herein prevent bacterial ingress, provide outflow resistance to retain a normal intraocular pressure, and provide moisture (e.g., aqueous humor) to an otherwise dry eye. Methods of treating a dry eye condition wherein the device is implanted in the sclera of an afflicted eye are also described.

Abstract: A new and novel system and method for reliably, securely, and affordably isolating and securing remote access to a secure cloud-based server and database, specifically, a NicheRMS police database, through a secured application, such as the NicheRMS application, over a secure network connection, such as a Citrix Independent Computing Architecture (ICA) connection, wherein the data in the sensitive database is accessed, and only present in a secured workspace and never transmitted locally to the endpoint devices.

Abstract: Vacuum cleaning devices include foldable wands to provide a storage configuration and/or facilitate use. A vacuum cleaning device includes a wand having a first end coupled to a vacuum unit and a second end coupled to a vacuum head or surface cleaning head. The wand defines an air passage allowing air to pass from the surface cleaning head to the vacuum unit and includes a flexible air passage along at least a portion of the wand. The wand also includes a plurality of segments pivotably connected together such that the wand is foldable about 180° in a forward direction until the vacuum unit is positioned proximate a top of the surface cleaning head, thereby providing a storage configuration.

Abstract: A gas turbine engine for an aircraft. The engine comprising: an engine core comprising a turbine, a compressor, a fan located upstream of the compressor and comprising a plurality of fan blades, and a core shaft connecting the turbine to the compressor; a gearbox which receives an input from the core shaft and outputs drive, via a driveshaft, to the fan so as to drive the fan at a lower rotational speed than the turbine, the drive shaft and core shaft forming a shaft system.

Abstract: Techniques described herein are directed to using blockchains to record, manage, and transfer ownership rights to land titles. A method in accordance with these techniques may include: creating a property blockchain that is permissioned, the property blockchain including a chronologically ordered, back-linked list of one or more blocks, the one or more blocks including a genesis block, the genesis block including property attributes including one more of the following: a physical address of the property, a year the property was built, and an owner of the property; and transmitting the property blockchain to permissioned nodes on a network, where the permissioned nodes validate transactions associated with the property that are recorded on the property blockchain.

Abstract: Described herein are compounds, including pharmaceutically acceptable salts, solvates, metabolites, prodrugs thereof, methods of making such compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat non-alcoholic steatohepatitis and other diseases characterized by dysfunctional tissue healing and fibrosis.

Abstract: Light emitting diode (LED) light tubes having rotatable end cap assemblies are described. The LED light tubes include a hollow tube and a circuit board with LED chips thereon. The end cap assemblies are provided on either end of the tube. Each end cap assembly includes a socket cap, a plug having a plug body and at least one connector, and an end cap body, one end of which engages one of the ends of the hollow tube. A cam locking mount that is positioned within the plug body and on the opposite side has projections to be positioned in the bore of the end cap body. A rotation cam is seated in the cam locking mount and provides for controlled rotation of the LED tube relative to the end caps. Methods of installing the LED light tubes in new installations and retrofit installations and for use in sign assemblies are also described.

Abstract: A family of lighting systems uses a small number of standard parts or extrusions. The extrusions include end elements, spars, and heat sinks. Lightbars and uplights, having heat sinks, LED arrays, and lenses, use heat sinks with the same extrusion profile. The extruded parts can be slid together and then held in place by screws holding side panels to form a housing. Conditioned electrical power can drive the LED arrays. The conditioned power can be produced by power conditioners mounting on the housing. IP65, or better, components can be used to produce a rugged outdoor system.

Abstract: A surface cleaning head with a leading roller may be used to facilitate capturing of debris in the air flow into a suction conduit on the underside of the surface cleaning head. The leading roller is generally positioned adjacent to and in advance of the opening of the suction conduit. The surface cleaning head may have dual agitators—a leading roller and a rotating brush roll—with the leading roller being located in front of the brush roll. The leading roller may have a smaller diameter than the brush roll and may provide a softer cleaning element. The leading roller may also have a bottom portion exposed to the flow path to the suction conduit and at least a top half that is not exposed to that flow path. The leading roller may also float relative to the surface cleaning head and/or may be adjustable relative to the brush roll.

Abstract: A trailer marker system including side markers and a round marker is disclosed herein. The side markers are to extend along the side of a trailer or trailer vehicle. The side markers are elongated lights, while the round marker is a circular shaped light. The side markers and round marker illuminate the surroundings of a trailer vehicle for increased safety. Importantly, each of the side markers and rear marker include lights that face down towards the roadway. This results in road markings being illuminated as to allow a driver of the trailer vehicles to safely remain on the road. Additionally, the downward facing lights found in the side markers and the rear marker help to eliminate blind spots. Blind spots when making a turn or reversing the trailer are eliminated as they are illuminated in order to allow the driver to be safer when operating the trailer vehicle.

Abstract: A fire resistant door leaf (30, 32) comprises a core (42) and a lipping (50, 52) extending along at least one edge (40) of the core (42). The lipping (50, 52) is of plastic material (60) and is bonded to the edge (40) of the core, and comprises at least one strip of intumescent material (62) extending parallel to the edge (40) of the core. The at least one strip of intumescent material (62) is covered by the plastic material (60) of the lipping, and the plastic material (60) is cast or moulded against the at least one strip of intumescent material (62). The fire resistant door leaf (30, 32) may be formed by locating the at least one strip of intumescent material (62) along the edge (40) of the core and subsequently forming the lipping (50, 52) by casting or moulding the plastic material (60) of the lipping to the core in a liquid or semi-liquid state to cover the at least one strip of intumescent material (62) and curing the plastic material in situ (60).

Abstract: A system is described that can detect, track and analyze a bubble of a secondary substance contained within a primary substance along a part of a fluid line. For example, the system can detect the presence of the bubble within the primary substance along the part of the fluid line, which can include assigning a digital signature to the bubble. In addition, the system can track the movement of the bubble in order to ensure that the bubble is accounted for only once as it passes through the part of the fluid line. Furthermore, the system can analyze the bubble, such as determine its direction of travel, speed of travel, volume and size.

Abstract: Light emitting diode (LED) light tubes having rotatable end caps assemblies are described. The LED light tubes include a hollow tube and a circuit board with LED chips thereon. The rotatable end cap assemblies are provided on either end of the tube. Each rotatable end cap assembly includes a socket cap, a plug having a plug body and at least one connector, and an end cap body, one end of which engages one of the ends of the hollow tube. A cam locking mount is positioned within the plug body and on the opposite side has projections to be positioned in the bore of the end cap body. A rotation cam is seated in the cam locking mount and provides for controlled rotation of the LED tube relative to the end caps. Methods of installing the LED light tubes in new installations and retrofit installations and for use in sign assemblies are also described.

Abstract: Techniques described herein are directed to using blockchains to record, manage, and transfer ownership rights to land titles. A method in accordance with these techniques may include: creating a property blockchain that is permissioned, the property blockchain including a chronologically ordered, back-linked list of one or more blocks, the one or more blocks including a genesis block, the genesis block including property attributes including one more of the following: a physical address of the property, a year the property was built, and an owner of the property; and transmitting the property blockchain to permissioned nodes on a network, where the permissioned nodes validate transactions associated with the property that are recorded on the property blockchain.

Abstract: A control unit is provided to improve positioning of transporting devices to thereby allow transporting devices to be driven at faster speeds and/or accelerations with minimal positional errors allowing for a reduction in the spacing between transporting devices. A control unit is arranged to control movement of at least one transporting device for containers stored in a facility having a plurality of pathways arranged in cells so as to form a grid-like structure above the stacks which extends in a first direction and in a second direction. The control unit includes a receiving unit arranged to receive information from a first sensor mounted on the at least one transporting device, and a calculating unit arranged to calculate a position of the at least one transporting device based on the receiPved information.

Abstract: A family of lighting systems uses a small number of standard parts or extrusions. The extrusions include end elements, spars, and heat sinks. Lightbars and uplights, having heat sinks, LED arrays, and lenses, use heat sinks with the same extrusion profile. The extruded parts can be slid together and then held in place by screws holding side panels to form a housing. Conditioned electrical power can drive the LED arrays. The conditioned power can be produced by power conditioners mounting on the housing. IP65, or better, components can be used to produce a rugged outdoor system.

Abstract: Described herein is the use of sulindac in the treatment of fragile X syndrome (FXS).

Abstract: A luminaire for architectural, industrial and warehouse applications can be assembled using an extruded housing having curved sides connected by a cross member. Window openings in the curved sides can allow light to exit toward the sides of the luminaire while most of the light exits through a lens on the bottom. The extrusion can have channels and slots such that optical elements and an LED array can be slid into the housing and retained by endcaps. A housing cover can overlie a wireway while being held in place by screws creating a clamping force between the housing cover and fixture brackets retained within the housing. The luminaire can be suspended by the fixture brackets or by elements attached to the fixture brackets.

Abstract: A miniature camera having an image sensor; an actuator which includes conductive components capable of conducting a pulse width modulation drive signal for driving the actuator; and a screening component located between the conductive components of the actuator and the image sensor, the screening component being electrically isolated from the actuator.