Abstract: The disclosed technology includes a surgical adjunct that includes bioabsorbable material such as a polyurethane foam. A volumetric ratio of the polyurethane foam to the total volume of the surgical adjunct may be in a range of about 0.125 to about 0.325. A glass transition temperature of the surgical adjunct may be about 0° C. to about 40° C.

Abstract: The disclosed technology includes a surgical adjunct includes a polyurethane foam and a film disposed on at least one surface of the polyurethane foam. A volumetric ratio of the polyurethane foam to the total volume of the surgical adjunct 604 is in a range of about 0.125 to about 0.325.

Abstract: A method for using a surgical instrument comprises translating a first translatable member to unlock an articulation joint, translating a second translatable member to articulate and end effector at the articulation joint, and translating the second translatable member again to lock the articulation joint. The first and second translatable members may be translatable independently of each other. The act of unlocking an articulation joint may include moving a locking feature along a plane that is parallel to both the longitudinal axis of a shaft assembly and an articulation axis of the articulation joint. The locking feature may move longitudinally along the articulation axis, perpendicular to the longitudinal axis of the shaft assembly.

Abstract: An apparatus comprises a body, a shaft assembly, an end effector, and an articulation joint. The end effector is operable to manipulate (e.g., staple) tissue. The articulation joint couples the end effector with the shaft assembly and permits the end effector to deflect away from the longitudinal axis of the shaft assembly. The articulation joint comprises a locking assembly, which is operable to selectively lock the angular position of the end effector relative to the longitudinal axis. The locking assembly comprises a first locking member and a second locking member. The first locking member is unitarily secured to the end effector. The second locking member is movable along a first axis to selectively engage the first locking member to thereby selectively lock the angular position of the end effector relative to the longitudinal axis of the shaft assembly. The first axis is perpendicular to the longitudinal axis.

Abstract: An apparatus comprises a body, a shaft assembly, an end effector, and an articulation joint. The end effector is operable to manipulate (e.g., staple) tissue. The articulation joint couples the end effector with the shaft assembly and permits the end effector to deflect away from the longitudinal axis of the shaft assembly. The articulation joint comprises a locking assembly, which is operable to selectively lock the angular position of the end effector relative to the longitudinal axis. The locking assembly comprises a first locking member and a second locking member. The first locking member is unitarily secured to the end effector. The second locking member is movable along a first axis to selectively engage the first locking member to thereby selectively lock the angular position of the end effector relative to the longitudinal axis of the shaft assembly. The first axis is perpendicular to the longitudinal axis.

Abstract: A method for using a surgical instrument comprises translating a first translatable member to unlock an articulation joint, translating a second translatable member to articulate and end effector at the articulation joint, and translating the second translatable member again to lock the articulation joint. The first and second translatable members may be translatable independently of each other. The act of unlocking an articulation joint may include moving a locking feature along a plane that is parallel to both the longitudinal axis of a shaft assembly and an articulation axis of the articulation joint. The locking feature may move longitudinally along the articulation axis, perpendicular to the longitudinal axis of the shaft assembly.

Abstract: The present invention relates to the use of antibodies directed against specific histone amino terminus modifications as diagnostic indicators of disease or congenital defects. In one embodiment, nucleosomes are isolated from a blood or serum sample of a patient using histone specific antibodies and the accompanying DNA is purified and analyzed for diagnostic and screening purposes.

Abstract: Immunochemical assays for human amylase isoenzymes are disclosed. These assays utilize monoclonal antibodies which are produced from hybridoma cell lines and are specific for human salivary amylase and ovarian tumor amylase but not human pancreatic amylase. The assays involve reacting this monoclonal antibody with the unknown sample for the purpose of studying quantitatively and qualitatively the amylase isoenzymes present. The results from such assays are useful in the diagnosis of disease or ruling out disease. Antibody producing hybridoma cell lines and their production are described.