Patents by Inventor David Bryce

David Bryce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230172975
    Abstract: The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are “clean” relative to the surfaces of metal-based nanoparticles made using chemical reduction (and other) processes that require organic (or other) reductants and/or surfactants to grow (and/or suspend) metal nanoparticles from metal ions in a solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the bi-metallic nanocrystal suspensions. The techniques do not require the use or presence of chlorine ions/atoms and/or chlorides or chlorine-based materials for the manufacturing process/final suspension.
    Type: Application
    Filed: March 30, 2022
    Publication date: June 8, 2023
    Applicant: GR Intellectual Reserve, LLC
    Inventors: Adam R. Dorfman, David A. Bryce, Maxwell A. Grace, D. Kyle Pierce, Mikhail Merzliakov, Mark G. Mortenson
  • Patent number: 11487646
    Abstract: Systems, methods, and machine-readable instructions stored on machine-readable media are disclosed for adjusting a time limit for a test based on one or more indications of availability. A test is executed, wherein the test includes a time limit. A determination is made that the time limit is exceeded. In response, the time limit is adjusted based on one or more indications of availability.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: November 1, 2022
    Assignee: Red Hat, Inc.
    Inventors: Steven Francis Best, David Bryce Arcari
  • Publication number: 20210397442
    Abstract: A method includes, receiving a first version of a software patch for an application. The method further includes receiving a second version of the software patch, the second version being associated with an upstream version of the application. The method further includes, comparing the first version of the software patch with the second version of the software patch, the comparing accounting for differences between the first version of the software patch and the second version of the software patch that result from differences between the application and the upstream version of the application. The method further includes, in response to comparing, tagging the first version of the software patch as a match when there are no differences other than the differences between the first version of the software patch and the second version of the software patch that result from differences between the application and the upstream version of the application.
    Type: Application
    Filed: June 23, 2020
    Publication date: December 23, 2021
    Inventors: Steven Francis Best, David Bryce Arcari
  • Publication number: 20210392899
    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. The continuous process causes at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s).
    Type: Application
    Filed: April 12, 2021
    Publication date: December 23, 2021
    Applicant: Clene Nanomedicine
    Inventors: David K. Pierce, Mark G. Mortenson, David A. Bryce
  • Patent number: 11204759
    Abstract: A method includes, receiving a first version of a software patch for an application. The method further includes receiving a second version of the software patch, the second version being associated with an upstream version of the application. The method further includes, comparing the first version of the software patch with the second version of the software patch, the comparing accounting for differences between the first version of the software patch and the second version of the software patch that result from differences between the application and the upstream version of the application. The method further includes, in response to comparing, tagging the first version of the software patch as a match when there are no differences other than the differences between the first version of the software patch and the second version of the software patch that result from differences between the application and the upstream version of the application.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: December 21, 2021
    Assignee: RED HAT, INC.
    Inventors: Steven Francis Best, David Bryce Arcari
  • Publication number: 20210361699
    Abstract: The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic impurities or films. Specifically, the surfaces are “clean” relative to the surfaces of gold nanoparticles made using chemical reduction processes that require organic reductants and/or surfactants to grow gold nanoparticles from gold ions in solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the gold-based nanocrystals. The invention further includes pharmaceutical compositions thereof and the use of the gold nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which gold therapy is already known and more generally for conditions resulting from pathological cellular activation, such as inflammatory (including chronic inflammatory) conditions, autoimmune conditions, hypersensitivity reactions and/or cancerous diseases or conditions.
    Type: Application
    Filed: April 13, 2021
    Publication date: November 25, 2021
    Applicant: Clene Nanomedicine, Inc.
    Inventors: Mark Gordon Mortenson, D. Kyle Pierce, David A. Bryce, Reed N. Wilcox, Anthony Lockett, Mikhail Merzliakov
  • Publication number: 20210236542
    Abstract: The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic impurities or films. Specifically, the surfaces are “clean” relative to the surfaces of gold nanoparticles made using chemical reduction processes that require organic reductants and/or surfactants to grow gold nanoparticles from gold ions in solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the gold-based nanocrystals. The invention further includes pharmaceutical compositions thereof and the use of the gold nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which gold therapy is already known and more generally for conditions resulting from pathological cellular activation, such as inflammatory (including chronic inflammatory) conditions, autoimmune conditions, hypersensitivity reactions and/or cancerous diseases or conditions.
    Type: Application
    Filed: April 6, 2021
    Publication date: August 5, 2021
    Applicant: Clene Nanomedicine, Inc.
    Inventors: Mark Gordon Mortenson, D. Kyle Pierce, David A. Bryce, Reed N. Wilcox, Anthony Lockett, Mikhail Merzliakov
  • Patent number: 11054356
    Abstract: A particle characterisation apparatus comprising: a light source for illuminating a sample with a light beam; a detector arranged to detect scattered light from the interaction of the light beam with the sample; a focus tuneable lens arranged to collect the scattered light for the detector from a scattering volume and/or to direct the light beam into the sample, a sample holder with an opposed pair of electrodes and configured to hold a sample in position in a measurement volume between the pair of electrodes such that a planar surface of the sample is aligned orthogonally to the electrode surfaces, the planar surface adjacent to the scattering volume, wherein adjustment of the focus tuneable lens results in adjustment of the relative position of the planar surface and the scattering volume by moving the scattering volume.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: July 6, 2021
    Assignee: Malvern Panalytical Limited
    Inventors: Jason Cecil William Corbett, David Bryce
  • Patent number: 11000042
    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. The continuous process causes at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s).
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: May 11, 2021
    Inventors: David K. Pierce, Mark G. Mortenson, David A. Bryce
  • Publication number: 20210124310
    Abstract: A solid state light shadow clock including construction of multiple light sources about the perimeter illuminated inward to cast shadows displaying apparent rotation about the center at the speed of clock hands; at a speed of one revolution per hour, at the speed of one revolution per twelve hours, and at the speed of one revolution per minute; a circumferential inward facing arrangement of light emitting devices to cast shadows at various lengths and color combinations. The clock comprises radial shadows cast in representation of the arms of a clock. The shadow clock display may be incorporated in devices ranging in size from portable devices to large public displays.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 29, 2021
    Inventor: DAVID BRYCE TURNER
  • Patent number: 10980832
    Abstract: The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic impurities or films. Specifically, the surfaces are “clean” relative to the surfaces of gold nanoparticles made using chemical reduction processes that require organic reductants and/or surfactants to grow gold nanoparticles from gold ions in solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the gold-based nanocrystals. The invention further includes pharmaceutical compositions thereof and the use of the gold nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which gold therapy is already known and more generally for conditions resulting from pathological cellular activation, such as inflammatory (including chronic inflammatory) conditions, autoimmune conditions, hypersensitivity reactions and/or cancerous diseases or conditions.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: April 20, 2021
    Assignee: Clene Nanomedicine, Inc.
    Inventors: Mark Gordon Mortenson, D. Kyle Pierce, David A. Bryce, Reed N. Wilcox, Anthony Lockett, Mikhail Merzliakov
  • Publication number: 20210052638
    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created and/or the liquid is predisposed to their presence (e.g., conditioned)) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred.
    Type: Application
    Filed: October 9, 2019
    Publication date: February 25, 2021
    Applicant: Clene Nanomedicine, Inc.
    Inventors: David Kyle Pierce, Mark G. Mortenson, David A. Bryce
  • Publication number: 20200278919
    Abstract: Systems, methods, and machine-readable instructions stored on machine-readable media are disclosed for adjusting a time limit for a test based on one or more indications of availability. A test is executed, wherein the test includes a time limit. A determination is made that the time limit is exceeded. In response, the time limit is adjusted based on one or more indications of availability.
    Type: Application
    Filed: March 1, 2019
    Publication date: September 3, 2020
    Inventors: Steven Francis Best, David Bryce Arcari
  • Publication number: 20200188429
    Abstract: The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic impurities or films. Specifically, the surfaces are “clean” relative to the surfaces of gold nanoparticles made using chemical reduction processes that require organic reductants and/or surfactants to grow gold nanoparticles from gold ions in solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the gold-based nanocrystals. The invention further includes pharmaceutical compositions thereof and the use of the gold nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which gold therapy is already known and more generally for conditions resulting from pathological cellular activation, such as inflammatory (including chronic inflammatory) conditions, autoimmune conditions, hypersensitivity reactions and/or cancerous diseases or conditions.
    Type: Application
    Filed: August 8, 2019
    Publication date: June 18, 2020
    Applicant: Clene Nanomedicine, Inc.
    Inventors: Mark Gordon Mortenson, D. Kyle Pierce, David A. Bryce, Reed N. Wilcox, Anthony Lockett, Mikhail Merzliakov
  • Publication number: 20200166446
    Abstract: A particle characterisation apparatus comprising: a light source for illuminating a sample with a light beam; a detector arranged to detect scattered light from the interaction of the light beam with the sample; a focus tuneable lens arranged to collect the scattered light for the detector from a scattering volume and/or to direct the light beam into the sample, a sample holder with an opposed pair of electrodes and configured to hold a sample in position in a measurement volume between the pair of electrodes such that a planar surface of the sample is aligned orthogonally to the electrode surfaces, the planar surface adjacent to the scattering volume, wherein adjustment of the focus tuneable lens results in adjustment of the relative position of the planar surface and the scattering volume by moving the scattering volume.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 28, 2020
    Applicant: Malvern Panalytical Limited
    Inventors: Jason Cecil William CORBETT, David BRYCE
  • Patent number: 10449217
    Abstract: The present invention relates to novel gold nanocrystals and nanocrystal shape distributions that have surfaces that are substantially free from organic impurities or films. Specifically, the surfaces are “clean” relative to the surfaces of gold nanoparticles made using chemical reduction processes that require organic reductants and/or surfactants to grow gold nanoparticles from gold ions in solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the gold-based nanocrystals. The invention further includes pharmaceutical compositions thereof and the use of the gold nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which gold therapy is already known and more generally for conditions resulting from pathological cellular activation, such as inflammatory (including chronic inflammatory) conditions, autoimmune conditions, hypersensitivity reactions and/or cancerous diseases or conditions.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: October 22, 2019
    Assignee: Clene Nanomedicine, Inc.
    Inventors: Mark Gordon Mortenson, D. Kyle Pierce, David A. Bryce, Reed N. Wilcox, Anthony Lockett, Mikhail Merzliakov
  • Patent number: 10441608
    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created and/or the liquid is predisposed to their presence (e.g., conditioned)) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: October 15, 2019
    Assignee: Clene Nanomedicine, Inc.
    Inventors: David Kyle Pierce, Mark G. Mortenson, David A. Bryce
  • Patent number: 10365198
    Abstract: A particle characterization apparatus comprising: a light source for illuminating a sample with a light beam; a detector arranged to detect scattered light from the interaction of the light beam with the sample; and a focus tuneable lens arranged to collect the scattered light for the detector from a scattering volume and/or to direct the light beam into the sample.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: July 30, 2019
    Assignee: Malvern Panalytical Limited
    Inventors: Jason Cecil William Corbett, David Bryce
  • Publication number: 20190059386
    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. The continuous process causes at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s).
    Type: Application
    Filed: August 31, 2018
    Publication date: February 28, 2019
    Applicant: Clene Nanomedicine, Inc.
    Inventors: David K. Pierce, Mark G. Mortenson, David A. Bryce
  • Patent number: 10092007
    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. The continuous process causes at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s).
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: October 9, 2018
    Assignee: Clene Nanomedicine, Inc.
    Inventors: David K. Pierce, Mark G. Mortenson, David A. Bryce