Patents by Inventor David Bunka

David Bunka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230228751
    Abstract: The invention relates to one or more aptamers isolated against the SARS-CoV-2 spike protein and methods of using the same. Certain embodiments of the invention relate to methods of detecting the presence, absence or amount of SARS-CoV-2 in a sample using the one or more aptamers described herein. In certain embodiments, the invention relates to one or more aptamers that are capable of specifically binding to SARS-CoV-2 proteins, including aptamers that are capable of specifically binding to the S1 subunit (including the receptor binding domain (RBD)) and/or the S2 subunit within their native conformation as part of the SARS-CoV-2 spike protein in its trimeric form or as separate monomers.
    Type: Application
    Filed: June 18, 2021
    Publication date: July 20, 2023
    Inventors: Arron TOLLEY, David BUNKA, Edward BARNES, Banushan BALANSETHUPATHY, Harriet FLYNN, Janice ROBOTTOM, Laura MILBURN, Phoebe O'HARA, Joe REED
  • Publication number: 20220307029
    Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 29, 2022
    Inventors: Ronald J. Shannon, Michael McIntyre, David Bunka, Edward Barnes
  • Publication number: 20220049258
    Abstract: The present invention relates inter alia to aptamers that specifically bind to Irinotecan and methods of using the same.
    Type: Application
    Filed: November 27, 2019
    Publication date: February 17, 2022
    Inventors: Katarzyna BIALAS, Christine REINEMANN, Edward BARNES, David BUNKA, Aaron TOLLEY
  • Publication number: 20210332362
    Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
    Type: Application
    Filed: April 13, 2021
    Publication date: October 28, 2021
    Inventors: Ronald J. Shannon, Michael McIntyre, David Bunka, Edward Barnes
  • Patent number: 11104905
    Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: August 31, 2021
    Assignee: Biovector, Inc.
    Inventors: Ronald J. Shannon, Michael McIntyre, David Bunka, Edward Barnes
  • Patent number: 11001847
    Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: May 11, 2021
    Assignee: Biovector, Inc.
    Inventors: Ronald J. Shannon, Michael McIntyre, David Bunka, Edward Barnes
  • Publication number: 20200385731
    Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
    Type: Application
    Filed: August 12, 2020
    Publication date: December 10, 2020
    Inventors: Ronald J. Shannon, Michael McIntyre, David Bunka, Edward Barnes
  • Publication number: 20200385730
    Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
    Type: Application
    Filed: June 5, 2020
    Publication date: December 10, 2020
    Inventors: Ronald J. Shannon, Michael McIntyre, David Bunka, Edward Barnes
  • Publication number: 20060234926
    Abstract: The present invention relates to novel nucleic acid molecules or ligands or aptamers with affinities for specific target molecules, and uses of such molecules. The target molecules are fibrillar proteins in all forms of the protein that is to say its monomeric, pre-fibrillar, protofibrillar and mature fibrillar forms. The molecules of the present invention are therefore useful as diagnostic or therapeutic or screening agents, or as potential lead compounds for ralionalised drug design.
    Type: Application
    Filed: November 5, 2003
    Publication date: October 19, 2006
    Inventors: Peter Stockley, Christopher Adams, David Bunka, Roma Rambaran, Simon Phillips, Sheena Radford