Abstract: Systems, apparatuses, and methods provide a tool for project and organizational risk awareness and management. The tool may take the form of a set of user interface elements, a set of processes, and a risk management methodology. The tool operates to combine risk assessment experts and technology experts into a common approach or function. This assists in providing a realistic assessment of the risk associated with a project or task, including its impact on an organization as a whole. The integrated risk evaluation and management platform may enable consideration of the mitigation steps that are presently being used, that may be available but are not presently being used, or that are required or should be considered to manage a type or source of risk.

Abstract: Large and complex data sets can be difficult to view on devices with small screens, such as on smartphones, or in small windows on devices with large screens. The presently disclosed systems, methods and apparatus can determine characteristics associated with a display used to display a requested resource. Based on these determined characteristics, the systems and methods can determine whether the requested resource should be reformatted to fit the display. The requested resource can be reformatted to allow a user to consume complex data on a small display easily and effectively. In some embodiments, this can be done by ensuring that the current data context, previously provided by row/column headers, are always in view in a compact format.

Abstract: A method for dealing with the effects of inertia in a radiotherapy apparatus is disclosed. The method may include catering for inertia in advance by incorporating inertia factors into an output from a delivery control system which adapts the treatment plan by incorporating the inertia factors, or by including the inertia factors as a constraint in the treatment planning process. The instructions delivered to the geometry items may reflect their inertia behavior and can therefore be followed very closely. This may indicate that a departure from that plan will be correspondingly more likely to indicate an error by the geometry item. When a geometry item needs to accelerate or decelerate, less error may arise and thus the error-checking regime may not necessarily make allowances for such departures from the intended path, thereby tightening the error tolerances. Error-checking may be safely carried out locally for each component.

Abstract: Large and complex data sets can be difficult to view on devices with small screens, such as on smartphones, or in small windows on devices with large screens. The presently disclosed systems, methods and apparatus can determine characteristics associated with a display used to display a requested resource. Based on these determined characteristics, the systems and methods can determine whether the requested resource should be reformatted to fit the display. The requested resource can be reformatted to allow a user to consume complex data on a small display easily and effectively. In some embodiments, this can be done by ensuring that the current data context, previously provided by row/column headers, are always in view in a compact format.

Abstract: A method for dealing with the effects of inertia in a radiotherapy apparatus is disclosed. The method may include catering for inertia in advance by incorporating inertia factors into an output from a delivery control system which adapts the treatment plan by incorporating the inertia factors, or by including the inertia factors as a constraint in the treatment planning process. The instructions delivered to the geometry items may reflect their inertia behavior and can therefore be followed very closely. This may indicate that a departure from that plan will be correspondingly more likely to indicate an error by the geometry item. When a geometry item needs to accelerate or decelerate, less error may arise and thus the error-checking regime may not necessarily make allowances for such departures from the intended path, thereby tightening the error tolerances. Error-checking may be safely carried out locally for each component.

Abstract: The invention is concerned with a continuously variable transmission incorporating a variator of the type having at least two co-axial races (D1-D4) between which drive is transferred at a continuously variable variator ratio. The variator races are mounted for rotation about a variator shaft (15). The transmission has a layshaft (18) which is laterally separated from the variator shaft. It has two epicyclic gears. A splitter epicyclic (14) has an input member driven from the transmission input (10) and two output members arranged respectively to drive the layshaft and the variator shaft. A recirculater epicyclic has first and second input members for coupling respectively to the variator shaft and to the layshaft and a recirculater output member. An arrangement of clutches is provided for selectively engaging any of at least three regimes. In one regime the recirculater output member drives the transmission output. In another the layshaft drives the transmission output.

Abstract: The invention is concerned with a continuously variable transmission incorporating a variator of the type having at least two co-axial races (D1-D4) between which drive is transferred at a continuously variable variator ratio. The variator races are mounted for rotation about a variator shaft (16). The transmission has a layshaft (18) which is laterally separated from the variator shaft. It has two epicyclic gears. A splitter epicyclic (14) has an input member driven from the transmission input (10) and two output members arranged respectively to drive the layshaft and the variator shaft. A recirculater epicyclic has first and second input members for coupling respectively to the variator shaft and to the layshaft and a recirculater output member. An arrangement of clutches is provided for selectively engaging any of at least three regimes. In one regime the recirculater output member drives the transmission output. In another the layshaft drives the transmission output.

Abstract: The invention is concerned with a continuously variable transmission incorporating a variator of the type having at least two co-axial races (D1-D4) between which drive is transferred at a continuously variable variator ratio. The variator races are mounted for rotation about a variator shaft (16). The transmission has a layshaft (18) which is laterally separated from the variator shaft. It has two epicyclic gears. A splitter epicyclic (14) has an input member driven from the transmission input (10) and two output members arranged respectively to drive the layshaft and the variator shaft. A recirculater epicyclic has first and second input members for coupling respectively to the variator shaft and to the layshaft and a recirculater output member. An arrangement of clutches is provided for selectively engaging any of at least three regimes. In one regime the recirculater output member drives the transmission output. In another the layshaft drives the transmission output.

Abstract: Immunogenic compositions for administration to adults particularly to the elderly, to protect them against disease caused by infection by respiratory syncytial virus and influenza virus comprise an immunoeffective amount of a mixture of purified fusion (F) protein, attachment (G) protein and matrix (M) protein of RSV and an immunoeffective amount of a non-virulent influenza virus preparation. The components of the composition when formulated as a vaccine for in vivo administration do not impair the immunogenicity of each other. The immunogenic composition may also contain an adjuvant.

Abstract: A method is shown for treating oil field waste waters associated with drilling, completion and production operations. An ozonation process is used as a pre-treatment to a flocculation process in the continuous treatment of oil field drilling and production reserve pit waste water. The treated water has been found to meet recycled re-use quality standards for re-use in oil field applications or to meet discharge parameters for ground disposal.

Abstract: Immunogenic compositions for administration to adults, particularly to the elderly, to protect them against disease caused by infection by respiratory syncytial virus and by influenza virus comprise an immunoeffective amount of a mixture of purified fusion (F) protein, attachment (G) protein and matrix (M) protein of RSV and an immunoeffective amount of a non-virulent influenza virus preparation. The components of the composition, when formulated as a vaccine for in vivo administration, do not impair the immunogenicity of each other. The immunogenic composition may also contain an adjuvant.

Abstract: The present disclosure relates to compositions and methods for treating or preventing coronavirus infections. For example, compositions are provided that comprise a coronavirus S protein or N protein, fragment, or variant thereof, capable of eliciting a protective humoral and/or cell-mediated immune response, which compositions are useful for treating or preventing infection by coronavirus, such as the causative agent of SARS. Also, coronavirus S protein and N protein immunogen compositions are provided that include an adjuvant, such as Proteosome or Protollin, which may be used for treating or preventing infection caused by a coronavirus, such as a SARS coronavirus.

Abstract: Compositions useful for treating neurological disorders including neurodegenerative disorders associated with deleterious protein aggregation, aberrant protein folding, such as brain amylogenic diseases, and/or neurodegenerative autoimmune disorders are described. Methods of using said compositions also are described. In particular, methods to treat a neurodegenerative disorder such as Alzheimer's disease and a neurodegenerative autoimmune disorder such as Multiple Sclerosis are contemplated utilizing proteosomes and/or Glatiramer Acetate, wherein the GA is in a submicron emulsion or a nanoemulsion.

Abstract: Immunogenic compositions for administration to adults particularly to the elderly, to protect them against disease caused by infection by respiratory syncytial virus and influenza virus comprise an immunoeffective amount of a mixture of purified fusion (F) protein, attachment (G) protein and matrix (M) protein of RSV and an immunoeffective amount of a non-virulent influenza virus preparation. The components of the composition when formulated as a vaccine for in vivo administration do not impair the immunogenicity of each other. The immunogenic composition may also contain an adjuvant.

Abstract: Compositions and methods for making and using therapeutic formulations of measles virus antigens with a Proteosome-based adjuvant are provided. The measles virus antigens may be derived from a variety of sources, such as from recombinant production or from a split antigen preparation. The measles vaccine formulations may be used, for example, in methods for treating or preventing a measles virus infection and eliciting a protective immune response.

Abstract: The present invention relates generally to methods of treating or preventing RSV infections, and more specifically, to compositions, and the use thereof, comprising one or more RSV G protein immunogen or fragment thereof capable of eliciting protective immunity without eliciting an immunopathological response or eliciting a reduced immunopathological response.

Abstract: Effective stimulation of immune responses is achieved through the use of a group A streptococcal antigen combined with proteosome adjuvant. The compositions are provided in particular for intranasal administration. The vaccine compositions are provided for use in inducing an immune response in an individual for the treatment or prophylaxis of group A streptococcal infection in an individual, preferably via prevention or reduction of colonisation of the throat following intranasal administration.

Abstract: A skimmer device for recovering a first liquid which is floating on a second liquid, e.g. oil on water, uses one or more discs rotating in a plane transverse to the liquid surface (preferably inclined at 70.degree. or less to the liquid surface). Particular benefits accrue, especially when operating in open water, when an inclination angle of 45.degree. or less is used. With a disc inclination angle of 25.degree.-30.degree. to the liquid surface a near optimal compromise is reached between oil take-up rate and ease of collection. Further advantages are obtained with skimmer discs of polymethyl methacrylate resin.

Abstract: Liquids, specifically liquids containing suspended matter, may be treated by passage through a separator comprising means dividing the container into a first section, intermediate section and third section, with a flat topped weir dividing the first section from the intermediate section. The width of the flat topped weir is selected so that liquid flow over the weir is laminar. At least the flat topped portion of the weir is provided with a smooth surface so as to reduce friction and boundary effects which distort the desired flow pattern. This smooth surface may be constituted by an L-shaped stainless steel plate. The interior side walls of the container in the vicinity of the flat top of the weir may be coated with a two-part epoxy to provide smooth surfaces.

Abstract: A tamperproof shackle seal comprising: a strap, a plug at one end of the strap, a housing at the other end of the strap, and a socket embedded within the housing; the strap, the plug and the housing having been integrally formed of a plastics material, and the socket having been separately formed of a plastics material; the plug including a leading end and a shoulder which faces away from said leading end; the housing having a sleeve-like wall which is integrally closed around the socket apart from at an open mouth; and the socket defining a cavity which is closed, apart from at an open entrance in alignment with said open mouth, with at least one resiliently deflectable portion of the socket protruding into said cavity; whereby, in use, said at least one resiliently deflectable portion flexes to permit insertion of the plug into the socket, and then abuts said shoulder to hold the plug captive in the socket.