Patents by Inventor David Bzik

David Bzik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attenuated uracil auxotroph of an apicomplexan and use thereof
    Patent number: 8293224
    Abstract: Uracil auxotroph mutants of apicomplexans are provided which lack a functional carbamoyl phosphate synthase II (CPSII) enzyme. Also provided are T. gondii autoxtroph mutants which express exogenous antigens, and methods of protecting an animal against a T. gondii and non-T. gondii disease.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: October 23, 2012
    Assignee: Trustees of Dartmouth College
    Inventors: David Bzik, Barbara Fox
  • Attenuated uracil auxotroph of an apicomplexan and use thereof
    Publication number: 20080124363
    Abstract: Uracil auxotroph mutants of apicomplexans are provided which lack a functional carbamoyl phosphate synthase II (CPSII) enzyme. Also provided are T. gondii autoxtroph mutants which express exogenous antigens, and methods of protecting an animal against a T. gondii and non-T. gondii disease.
    Type: Application
    Filed: December 21, 2007
    Publication date: May 29, 2008
    Inventors: David Bzik, Barbara Fox
  • Compositions and methods for treatment of Toxoplasma gondii and other apicomplexans
    Publication number: 20070172502
    Abstract: Pyrimidine auxotroph mutants of apicomplexans are provided which are mutated in one of six enzymes of the de novo pyrimidine biosynthesis pathway. Also provided are methods of protecting an animal against infection by apicomplexans by administering a pyrimidine auxotroph mutant and methods for screening for inhibitors of pyrimidine salvage enzymes in apicomplexans.
    Type: Application
    Filed: July 18, 2006
    Publication date: July 26, 2007
    Inventors: David Bzik, Barbara Fox