Patents by Inventor David C. Cipolla

David C. Cipolla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9259424
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: February 16, 2016
    Assignee: Aradigm Corporation
    Inventors: David C. Cipolla, James Blanchard
  • Publication number: 20150283076
    Abstract: Methods for formulating a liposome comprised of a surfactant and a cryopreservative that can be frozen for long term stability, and upon thawing provides an immediate and sustained release delivery profile. Specific liposome formulations include anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: February 11, 2015
    Publication date: October 8, 2015
    Applicant: ARADIGM CORPORATION
    Inventors: David C. CIPOLLA, Igor GONDA
  • Publication number: 20150283133
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: March 31, 2015
    Publication date: October 8, 2015
    Applicants: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor GONDA, James BLANCHARD, David C. CIPOLLA, LUIZ EDUARDO MOREIRA BERMUDEZ
  • Publication number: 20150202201
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Application
    Filed: April 1, 2015
    Publication date: July 23, 2015
    Inventors: DAVID C. CIPOLLA, JAMES BLANCHARD
  • Patent number: 9078897
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: July 14, 2015
    Assignee: ARADIGM CORPORATION
    Inventors: David C. Cipolla, James Blanchard
  • Patent number: 9028864
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: May 12, 2015
    Assignee: Aradigm Corporation
    Inventors: David C. Cipolla, James Blanchard
  • Publication number: 20150110855
    Abstract: Methods for formulating and compositions of immediate and sustained release liposomal products which comprise a surfactant that interacts with liposomes to effect drug release therefrom, and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 23, 2015
    Inventors: David C. CIPOLLA, Igor GONDA
  • Publication number: 20150071992
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 12, 2015
    Inventors: DAVID C. CIPOLLA, JAMES BLANCHARD
  • Patent number: 8414915
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: April 9, 2013
    Assignee: Aradigm Corporation
    Inventors: David C. Cipolla, James Blanchard
  • Publication number: 20120282328
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: July 13, 2012
    Publication date: November 8, 2012
    Inventors: DAVID C. CIPOLLA, JAMES BLANCHARD
  • Publication number: 20120244206
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: October 22, 2007
    Publication date: September 27, 2012
    Inventors: David C. Cipolla, James Blanchard
  • Patent number: 8268347
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: September 18, 2012
    Assignee: Aradigm Corporation
    Inventors: David C. Cipolla, James Blanchard
  • Publication number: 20120177693
    Abstract: Administration of aerosolized Treprostinil formulations may provide a more homogeneous lung deposition of treprostinil, whereby making deep lung delivery possible.
    Type: Application
    Filed: September 24, 2009
    Publication date: July 12, 2012
    Inventors: David C. Cipolla, Igor Gonda, Babatunde Otulana, Richard Morishige, Paul R. Bruinenberg
  • Patent number: 8119156
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: February 21, 2012
    Assignee: Aradigm Corporation
    Inventors: David C. Cipolla, James Blanchard
  • Patent number: 8071127
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: December 6, 2011
    Assignee: Aradigm Corporation
    Inventors: David C. Cipolla, James Blanchard
  • Publication number: 20110150983
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposomes which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 23, 2011
    Inventors: DAVID C. CIPOLLA, James Blanchard
  • Publication number: 20110104259
    Abstract: The present invention provides novel processes and methodologies to minimize the bitter or otherwise unpleasant taste, to minimize the tendency to stimulate the cough reflex, or to minimize oropharyngeal deposition of medically-active compounds administered by the pulmonary/inhalation route and to deliver hydroxychloroquine (HCQ) either singularly or in combination with an antimalarial and aminoquinolone by the pulmonary/inhalation route in a sustained release or other formulation that minimizes the bitter or otherwise unpleasant taste of HCQ or any potential to stimulate the cough reflex, and to deliver a dopaminergic compound or its prodrug, including ABT-431 by the pulmonary/inhalation route in a sustained release or other formulation that minimizes the unpleasant taste of the drug or any potential to stimulate the cough reflex, and to deliver a lantibiotic, including duramycin by the pulmonary/inhalation route in a sustained release or other formulation that minimizes the unpleasant taste of the drug or a
    Type: Application
    Filed: January 7, 2011
    Publication date: May 5, 2011
    Inventors: Jeffrey A. Schuster, David C. Cipolla, Stephen Farr
  • Publication number: 20110064796
    Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.
    Type: Application
    Filed: September 22, 2010
    Publication date: March 17, 2011
    Inventors: David C. Cipolla, James Blanchard
  • Publication number: 20100209538
    Abstract: An aerosolizable formulation comprised of a drug, a carrier and pH affecting component is disclosed. The drug is dissolved in the formulation at a concentration above which it remains in solution at neutral pH. This increases the concentration of the drug in solution making it possible to administer larger amounts of drug with the same or a smaller volume of formulation. When the formulation is aerosolized to small particles and inhaled into human lungs in small volumes (e.g. 0.05 to 0.5 mL) the fluids in the lungs neutralize the formulation causing the drug to participate out of solution. This results in the drug being delivered at a controlled rate below the rate at which drug is administered from a formulation initially at a neutral pH.
    Type: Application
    Filed: January 26, 2010
    Publication date: August 19, 2010
    Inventors: David C. Cipolla, Igor Gonda
  • Publication number: 20090274754
    Abstract: Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: May 8, 2009
    Publication date: November 5, 2009
    Inventors: David C. Cipolla, James Blanchard